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HADHA HADHA ECHS1 ECHS1 HMGCS1 HMGCS1 GAD2 GAD2 G1LH78_AILME G1LH78_AILME ACSM3 ACSM3 ACSM4 ACSM4 HMGCLL1 HMGCLL1 ACADS ACADS GAD1 GAD1 ACSM2B ACSM2B ACSM5 ACSM5 BDH1 BDH1 HMGCL HMGCL ALDH5A1 ALDH5A1 ACAT2 ACAT2 OXCT1 OXCT1 ACAT1 ACAT1 EHHADH EHHADH HMGCS2 HMGCS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (524 aa)
GAD2Glutamate decarboxylase 2. (585 aa)
G1LH78_AILMEUncharacterized protein. (295 aa)
ACSM3Acyl-CoA synthetase medium chain family member 3. (586 aa)
ACSM4Acyl-CoA synthetase medium chain family member 4. (580 aa)
HMGCLL13-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (209 aa)
ACADSAcyl-CoA dehydrogenase short chain. (414 aa)
GAD1Glutamate decarboxylase 1. (595 aa)
ACSM2BUncharacterized protein. (578 aa)
ACSM5Acyl-CoA synthetase medium chain family member 5. (582 aa)
BDH13-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa)
HMGCL3-hydroxy-3-methylglutaryl-CoA lyase. (325 aa)
ALDH5A1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (456 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
OXCT1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (520 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (431 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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