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| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (423 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (425 aa) |
| | PLD1 | Phospholipase D1. (1074 aa) |
| | RAB5A | RAB5A, member RAS oncogene family. (215 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1361 aa) |
| | KSR2 | Kinase suppressor of ras 2. (890 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (193 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1400 aa) |
| | SYNGAP1 | Synaptic Ras GTPase activating protein 1. (1322 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | RGL2 | Ral guanine nucleotide dissociation stimulator like 2. (781 aa) |
| | CALM2-2 | Calmodulin 2; Belongs to the calmodulin family. (148 aa) |
| | TEK | TEK receptor tyrosine kinase. (1127 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | G1L5E8_AILME | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (124 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa) |
| | IGF2 | Insulin like growth factor 2. (238 aa) |
| | INS-IGF2 | INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (212 aa) |
| | RASAL3 | RAS protein activator like 3. (996 aa) |
| | MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1339 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (271 aa) |
| | RRAS2 | RAS related 2. (175 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (992 aa) |
| | PAK5 | Non-specific serine/threonine protein kinase. (719 aa) |
| | RGL1 | Ral guanine nucleotide dissociation stimulator like 1. (803 aa) |
| | SHC2 | Uncharacterized protein. (486 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (485 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (171 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (733 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | PLA2G2E | Phospholipase A(2). (137 aa) |
| | PLA2G5 | Phospholipase A(2). (139 aa) |
| | PLA2G2D | Phospholipase A(2). (161 aa) |
| | RAB5B | RAB5B, member RAS oncogene family. (217 aa) |
| | PLA2G2F | Phospholipase A(2). (198 aa) |
| | PLA2G2C | Phospholipase A(2). (160 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | SHC3 | SHC adaptor protein 3. (492 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | NTRK2 | Tyrosine-protein kinase receptor. (838 aa) |
| | RAPGEF5 | Rap guanine nucleotide exchange factor 5. (731 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa) |
| | STK4 | Serine/threonine kinase 4. (487 aa) |
| | RASA3 | RAS p21 protein activator 3. (838 aa) |
| | PRKCG | Protein kinase C gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (697 aa) |
| | PLA2G12A | Phospholipase A2 group XIIA. (216 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (558 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (968 aa) |
| | PLA2G1B | Phospholipase A(2). (148 aa) |
| | ZAP70 | Tyrosine-protein kinase. (613 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (269 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1071 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (755 aa) |
| | ANGPT2 | Angiopoietin 2. (496 aa) |
| | NF1 | Neurofibromin 1. (2820 aa) |
| | RAP1A | RAP1A, member of RAS oncogene family. (184 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (551 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1369 aa) |
| | RAB5C | Uncharacterized protein. (216 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (106 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (747 aa) |
| | G1LKQ4_AILME | DUF1968 domain-containing protein. (125 aa) |
| | GNB5 | G protein subunit beta 5. (395 aa) |
| | PLA2G3 | Phospholipase A2 group III. (513 aa) |
| | GNG13 | G protein subunit gamma 13. (67 aa) |
| | EXOC2 | Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (794 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | RASGRP3 | RAS guanyl releasing protein 3. (690 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1360 aa) |
| | RALA | RAS like proto-oncogene A. (206 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (787 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa) |
| | RAP1B | Uncharacterized protein. (184 aa) |
| | RALB | RAS like proto-oncogene B. (212 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (320 aa) |
| | NFKB1 | Uncharacterized protein. (781 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (192 aa) |
| | AFDN | Afadin, adherens junction formation factor. (1801 aa) |
| | PLCG1 | Phosphoinositide phospholipase C. (1294 aa) |
| | GAB1 | GRB2 associated binding protein 1. (724 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1314 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | RASGRP4 | RAS guanyl releasing protein 4. (657 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (253 aa) |
| | GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1483 aa) |
| | GRIN2A | Glutamate ionotropic receptor NMDA type subunit 2A. (1328 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (239 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | PIK3R2 | Uncharacterized protein. (716 aa) |
| | PLA2G10 | Phospholipase A(2). (158 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (205 aa) |
| | EFNA3 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (238 aa) |
| | EFNA4 | Ephrin A4; Belongs to the ephrin family. (204 aa) |
| | SHC1 | SHC adaptor protein 1. (587 aa) |
| | RASSF1 | Ras association domain family member 1. (302 aa) |
| | EPHA2 | EPH receptor A2. (971 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (666 aa) |
| | RASSF5 | Ras association domain family member 5. (347 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | PAK3 | P21 (RAC1) activated kinase 3. (580 aa) |
| | GNG14 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1. (1275 aa) |
| | NGFR | Nerve growth factor receptor. (427 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa) |
| | RASA1 | RAS p21 protein activator 1. (1036 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa) |
| | PDGFD | Platelet derived growth factor D. (329 aa) |
| | CALML6 | Calmodulin like 6. (165 aa) |
| | GNB1 | G protein subunit beta 1. (340 aa) |
| | PLCE1 | Phosphoinositide phospholipase C. (2303 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | BRAP | BRCA1 associated protein. (633 aa) |
| | PIK3R3 | Uncharacterized protein. (507 aa) |
| | RRAS | RAS related. (180 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | ANGPT4 | Angiopoietin 4. (495 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (661 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | RASAL2 | RAS protein activator like 2. (1280 aa) |
| | BDNF | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (323 aa) |
| | FGF21 | Fibroblast growth factor 21; Belongs to the heparin-binding growth factors family. (211 aa) |
| | GNB2 | G protein subunit beta 2. (340 aa) |
| | EGF | Epidermal growth factor. (864 aa) |
| | TIAM1 | Uncharacterized protein. (829 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (351 aa) |
| | RASA4B | Uncharacterized protein. (805 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (277 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (822 aa) |
| | ANGPT1 | Angiopoietin 1. (410 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | SHOC2 | SHOC2 leucine rich repeat scaffold protein. (582 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (245 aa) |
| | RASGRF2 | Ras protein specific guanine nucleotide releasing factor 2. (1239 aa) |
| | FOXO4 | Forkhead box O4. (506 aa) |
| | TGFA | Transforming growth factor alpha. (146 aa) |
| | PLD2 | Phospholipase D2. (933 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) |
| | ABL1 | Tyrosine-protein kinase. (1150 aa) |
| | PLA2G4F | Phospholipase A2. (858 aa) |
| | PLA2G4D | Phospholipase A2. (825 aa) |
| | PLA2G4E | Phospholipase A2. (862 aa) |
| | RASA2 | Uncharacterized protein. (511 aa) |
| | GRIN1 | Glutamate ionotropic receptor NMDA type subunit 1. (969 aa) |
| | G1MDR0_AILME | Phospholipase A2. (1010 aa) |
| | HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa) |
| | LOC100471152 | Uncharacterized protein. (481 aa) |
| | ETS2 | Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa) |
| | PLA2G12B | Phospholipase A2 group XIIB. (195 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | RIN1 | Ras and Rab interactor 1. (791 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (416 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (193 aa) |
| | PAK6 | Non-specific serine/threonine protein kinase. (680 aa) |
| | RAC3 | Rac family small GTPase 3. (189 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (528 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (96 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | RASGRP2 | RAS guanyl releasing protein 2. (639 aa) |
| | BAD | BCL2 associated agonist of cell death. (210 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | PLAAT3 | Phospholipase A and acyltransferase 3. (162 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (809 aa) |
| | REL | REL proto-oncogene, NF-kB subunit. (592 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (228 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1420 aa) |
| | NGF | Nerve growth factor; Belongs to the NGF-beta family. (240 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa) |
| | ARF6 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | CALML5 | Calmodulin like 5. (149 aa) |
| | LOC100484770 | Uncharacterized protein; Belongs to the calmodulin family. (149 aa) |
| | GNG10 | G protein gamma domain-containing protein. (41 aa) |
