STRINGSTRING
TRPC4 TRPC4 SLIT1 SLIT1 DPYSL2 DPYSL2 PLXNA3 PLXNA3 RHOD RHOD SEMA3A SEMA3A SSH3 SSH3 SEMA3D SEMA3D SHH SHH EFNA5 EFNA5 PLXNB1 PLXNB1 MET MET ROBO1 ROBO1 PDK1 PDK1 SEMA6B SEMA6B NTN1 NTN1 SEMA6D SEMA6D DPYSL5 DPYSL5 NTN4 NTN4 PAK5 PAK5 PIK3R1 PIK3R1 PPP3CC PPP3CC TRPC6 TRPC6 SEMA4D SEMA4D RYK RYK PAK2 PAK2 SEMA5A SEMA5A NTNG2 NTNG2 SSH2 SSH2 PIK3CD PIK3CD EFNB2 EFNB2 WNT5B WNT5B RAF1 RAF1 SEMA5B SEMA5B GNAI3 GNAI3 SMO SMO PIK3CB PIK3CB SEMA4C SEMA4C PAK1 PAK1 NEO1 NEO1 BMPR1B BMPR1B TRPC3 TRPC3 UNC5C UNC5C EPHA5 EPHA5 SLIT2 SLIT2 EPHB6 EPHB6 NCK1 NCK1 ROCK1 ROCK1 EPHA1 EPHA1 GSK3B GSK3B RND1 RND1 LIMK2 LIMK2 SLIT3 SLIT3 UNC5A UNC5A KRAS KRAS EPHA4 EPHA4 ARHGEF12 ARHGEF12 NFATC3 NFATC3 PLXNA2 PLXNA2 EPHA3 EPHA3 PTPN11 PTPN11 PPP3CA PPP3CA RGMA RGMA SEMA3G SEMA3G MAPK1 MAPK1 EFNB1 EFNB1 SEMA7A SEMA7A CAMK2D CAMK2D PLCG1 PLCG1 PLXNC1 PLXNC1 RAC2 RAC2 MYL9 MYL9 PARD6G PARD6G HRAS HRAS UNC5D UNC5D PIK3CA PIK3CA PIK3R2 PIK3R2 EFNA1 EFNA1 EFNA3 EFNA3 EFNA4 EFNA4 ROBO2 ROBO2 WNT5A WNT5A PTCH1 PTCH1 EPHA2 EPHA2 SRGAP2 SRGAP2 PRKCA PRKCA SEMA3B SEMA3B GNAI2 GNAI2 NTNG1 NTNG1 TRPC5 TRPC5 SEMA3F SEMA3F PAK3 PAK3 SRC SRC SRGAP3 SRGAP3 RHOA RHOA MYL12B MYL12B BMP7 BMP7 RGS3 RGS3 BMPR2 BMPR2 EPHA7 EPHA7 NCK2 NCK2 NFATC2 NFATC2 PARD6B PARD6B RASA1 RASA1 PRKCZ PRKCZ EPHA6 EPHA6 CDK5 CDK5 FES FES PIK3R3 PIK3R3 CXCL12 CXCL12 RRAS RRAS PLCG2 PLCG2 SEMA4A SEMA4A WNT4 WNT4 EPHB4 EPHB4 EPHB2 EPHB2 PLXNA4 PLXNA4 MAPK3 MAPK3 LIMK1 LIMK1 CFL2 CFL2 SEMA6A SEMA6A PARD3 PARD3 NFATC4 NFATC4 FZD3 FZD3 GNAI1 GNAI1 SEMA3C SEMA3C ABL1 ABL1 ILK ILK NGEF NGEF SSH1 SSH1 LOC100471152 LOC100471152 FYN FYN MYL5 MYL5 SEMA3E SEMA3E PPP3CB PPP3CB EFNB3 EFNB3 EPHB3 EPHB3 SEMA4F SEMA4F NRAS NRAS PAK6 PAK6 DCC DCC CFL1 CFL1 NRP1 NRP1 RAC3 RAC3 ITGB1 ITGB1 PARD6A PARD6A SEMA4G SEMA4G UNC5B UNC5B NTN3 NTN3 BOC BOC SRGAP1 SRGAP1 L1CAM L1CAM PLXNB3 PLXNB3 LRRC4C LRRC4C LRRC4 LRRC4 CXCR4 CXCR4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRPC4Transient receptor potential cation channel subfamily C member 4. (982 aa)
SLIT1Slit guidance ligand 1. (1521 aa)
DPYSL2Dihydropyrimidinase like 2. (675 aa)
PLXNA3Plexin A3. (1881 aa)
RHODRas homolog family member D. (169 aa)
SEMA3ASemaphorin 3A. (772 aa)
SSH3Slingshot protein phosphatase 3. (650 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (777 aa)
SHHSonic hedgehog signaling molecule. (267 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (193 aa)
PLXNB1Plexin B1. (2135 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1400 aa)
ROBO1Roundabout guidance receptor 1. (1593 aa)
PDK1Protein-serine/threonine kinase. (419 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (684 aa)
NTN1Laminin N-terminal domain-containing protein. (276 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1073 aa)
DPYSL5Dihydropyrimidinase like 5. (568 aa)
NTN4Netrin 4. (628 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (733 aa)
PPP3CCSerine/threonine-protein phosphatase. (509 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (878 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (873 aa)
RYKReceptor like tyrosine kinase. (534 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
SEMA5ASemaphorin 5A. (1073 aa)
NTNG2Netrin G2. (548 aa)
SSH2Slingshot protein phosphatase 2. (1414 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (335 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
SEMA5BSemaphorin 5B. (1108 aa)
GNAI3G protein subunit alpha i3. (326 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (767 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1071 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (830 aa)
PAK1Non-specific serine/threonine protein kinase. (551 aa)
NEO1Neogenin 1. (1443 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (534 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (925 aa)
UNC5CUnc-5 netrin receptor C. (931 aa)
EPHA5EPH receptor A5. (1038 aa)
SLIT2Slit guidance ligand 2. (1543 aa)
EPHB6EPH receptor B6. (1025 aa)
NCK1Cytoplasmic protein. (378 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1353 aa)
EPHA1EPH receptor A1. (972 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
RND1Rho family GTPase 1. (232 aa)
LIMK2LIM domain kinase 2. (617 aa)
SLIT3Slit guidance ligand 3. (1384 aa)
UNC5AUnc-5 netrin receptor A. (896 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
EPHA4EPH receptor A4. (986 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1546 aa)
NFATC3Nuclear factor of activated T cells 3. (1075 aa)
PLXNA2Plexin A2. (1894 aa)
EPHA3EPH receptor A3. (984 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (419 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (777 aa)
MAPK1Mitogen-activated protein kinase. (320 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group). (607 aa)
CAMK2DProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (499 aa)
PLCG1Phosphoinositide phospholipase C. (1294 aa)
PLXNC1Plexin C1. (1561 aa)
RAC2Rac family small GTPase 2. (192 aa)
MYL9Myosin light chain 9. (178 aa)
PARD6GPar-6 family cell polarity regulator gamma. (271 aa)
HRASHRas proto-oncogene, GTPase. (253 aa)
UNC5DUnc-5 netrin receptor D. (924 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
PIK3R2Uncharacterized protein. (716 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
EFNA3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (238 aa)
EFNA4Ephrin A4; Belongs to the ephrin family. (204 aa)
ROBO2Roundabout guidance receptor 2. (1385 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
PTCH1Patched 1. (1438 aa)
EPHA2EPH receptor A2. (971 aa)
SRGAP2Uncharacterized protein. (934 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (666 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (741 aa)
GNAI2G protein subunit alpha i2. (355 aa)
NTNG1Netrin G1. (354 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5. (974 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (784 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
SRCTyrosine-protein kinase. (542 aa)
SRGAP3SLIT-ROBO Rho GTPase activating protein 3. (1100 aa)
RHOARas homolog family member A. (193 aa)
MYL12BMyosin light chain 12B. (172 aa)
BMP7Bone morphogenetic protein 7. (427 aa)
RGS3Regulator of G protein signaling 3. (1118 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1040 aa)
EPHA7EPH receptor A7. (998 aa)
NCK2NCK adaptor protein 2. (380 aa)
NFATC2Nuclear factor of activated T cells 2. (908 aa)
PARD6BPar-6 family cell polarity regulator beta. (370 aa)
RASA1RAS p21 protein activator 1. (1036 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (586 aa)
EPHA6EPH receptor A6. (1133 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (819 aa)
PIK3R3Uncharacterized protein. (507 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (88 aa)
RRASRAS related. (180 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (758 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
EPHB4EPH receptor B4. (990 aa)
EPHB2EPH receptor B2. (968 aa)
PLXNA4Uncharacterized protein. (203 aa)
MAPK3Mitogen-activated protein kinase. (351 aa)
LIMK1LIM domain kinase 1. (632 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
PARD3Uncharacterized protein. (843 aa)
NFATC4Nuclear factor of activated T cells 4. (954 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
GNAI1G protein subunit alpha i1. (354 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (497 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
ILKIntegrin linked kinase. (452 aa)
NGEFNeuronal guanine nucleotide exchange factor. (710 aa)
SSH1Slingshot protein phosphatase 1. (1040 aa)
LOC100471152Uncharacterized protein. (481 aa)
FYNTyrosine-protein kinase. (537 aa)
MYL5Myosin light chain 5. (172 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
PPP3CBSerine/threonine-protein phosphatase. (522 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
EPHB3EPH receptor B3. (999 aa)
SEMA4FSsemaphorin 4F. (770 aa)
NRASNRAS proto-oncogene, GTPase. (193 aa)
PAK6Non-specific serine/threonine protein kinase. (680 aa)
DCCDCC netrin 1 receptor. (811 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (226 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
RAC3Rac family small GTPase 3. (189 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
PARD6APar-6 family cell polarity regulator alpha. (346 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (830 aa)
UNC5BUnc-5 netrin receptor B. (947 aa)
NTN3Netrin 3. (503 aa)
BOCBOC cell adhesion associated, oncogene regulated. (1115 aa)
SRGAP1SLIT-ROBO Rho GTPase activating protein 1. (1085 aa)
L1CAML1 cell adhesion molecule. (1236 aa)
PLXNB3Plexin B3. (1932 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
LRRC4Leucine rich repeat containing 4. (650 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (357 aa)
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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