STRINGSTRING
SH3KBP1 SH3KBP1 SH3GL2 SH3GL2 SH3GL1 SH3GL1 CBL CBL TNS2 TNS2 CBLC CBLC MET MET CBLB CBLB M3YFM7_MUSPF M3YFM7_MUSPF DLC1 DLC1 SH3GLB2 SH3GLB2 MST1R MST1R SH3GL3 SH3GL3 TNS1 TNS1 TNS3 TNS3 SPRY2 SPRY2 SPRY1 SPRY1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SH3KBP1SH3 domain containing kinase binding protein 1. (691 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (325 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (368 aa)
CBLCbl proto-oncogene. (913 aa)
TNS2Tensin 2. (1449 aa)
CBLCCbl proto-oncogene C. (516 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1540 aa)
CBLBCbl proto-oncogene B. (983 aa)
M3YFM7_MUSPFSEFIR domain-containing protein. (557 aa)
DLC1DLC1 Rho GTPase activating protein. (1526 aa)
SH3GLB2SH3 domain containing GRB2 like, endophilin B2. (449 aa)
MST1RMacrophage stimulating 1 receptor. (1399 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (347 aa)
TNS1Tensin 1. (1873 aa)
TNS3Tensin 3. (1560 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
SPRY1Sprouty-like protein 1, antagonist of FGF signaling. (319 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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