STRINGSTRING
SMAD3 SMAD3 SMAD6 SMAD6 ACVR1C ACVR1C SMAD7 SMAD7 SMAD2 SMAD2 GDF11 GDF11 INHBC INHBC SMAD9 SMAD9 ACVR2B ACVR2B ACVR2A ACVR2A TGFB2 TGFB2 NODAL NODAL ZFYVE16 ZFYVE16 TGFBR1 TGFBR1 SMAD1 SMAD1 ZFYVE9 ZFYVE9 ACVR1B ACVR1B SKI SKI SMAD4 SMAD4 SMAD5 SMAD5 TGFBR2 TGFBR2 MSTN MSTN FST FST SMURF2 SMURF2 SMURF1 SMURF1 INHA INHA SKIL SKIL TGFB1 TGFB1 INHBA INHBA INHBB INHBB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD3Mothers against decapentaplegic homolog. (414 aa)
SMAD6Mothers against decapentaplegic homolog. (494 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
SMAD2Mothers against decapentaplegic homolog. (495 aa)
GDF11Growth differentiation factor 11. (404 aa)
INHBCInhibin subunit beta C. (353 aa)
SMAD9Mothers against decapentaplegic homolog. (432 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (484 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
TGFB2Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (414 aa)
NODALNodal growth differentiation factor. (348 aa)
ZFYVE16Zinc finger FYVE domain-containing protein. (1450 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (480 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1422 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (494 aa)
SKISKI proto-oncogene. (680 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (445 aa)
MSTNMyostatin. (375 aa)
FSTFollistatin. (344 aa)
SMURF2E3 ubiquitin-protein ligase. (739 aa)
SMURF1E3 ubiquitin-protein ligase. (725 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (368 aa)
SKILSKI like proto-oncogene. (664 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
INHBAInhibin subunit beta A. (424 aa)
INHBBInhibin subunit beta B. (238 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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