STRINGSTRING
TLE1 TLE1 PRICKLE1 PRICKLE1 BCL9 BCL9 M3XNJ2_MUSPF M3XNJ2_MUSPF ROR1 ROR1 LRP2 LRP2 WNT9A WNT9A WNT3A WNT3A FZD3 FZD3 VANGL1 VANGL1 LRP1 LRP1 TCF7L2 TCF7L2 M3XSG3_MUSPF M3XSG3_MUSPF PYGO1 PYGO1 FRZB FRZB DVL3 DVL3 CELSR1 CELSR1 M3XU23_MUSPF M3XU23_MUSPF NKD1 NKD1 M3XX61_MUSPF M3XX61_MUSPF LRP5 LRP5 FZD10 FZD10 ATCAY ATCAY BCL9L BCL9L WNT2B WNT2B VLDLR VLDLR ZNF408 ZNF408 SFRP2 SFRP2 LDLR LDLR M3Y377_MUSPF M3Y377_MUSPF DAAM1 DAAM1 LRP8 LRP8 PYGO2 PYGO2 CDCP2 CDCP2 INVS INVS ROR2 ROR2 WNT16 WNT16 TSPAN12 TSPAN12 WNT2 WNT2 TES TES DAB1 DAB1 CD320 CD320 LRP3 LRP3 M3Y969_MUSPF M3Y969_MUSPF APC2 APC2 WNT3 WNT3 WNT9B WNT9B GSK3B GSK3B TCF7L1 TCF7L1 WNT11 WNT11 LEF1 LEF1 DKK2 DKK2 RYK RYK SOST SOST WNT8A WNT8A TCF7 TCF7 FZD4 FZD4 DVL2 DVL2 LRPAP1 LRPAP1 JUP JUP NOTUM NOTUM M3YJ32_MUSPF M3YJ32_MUSPF CUBN CUBN CTNNB1 CTNNB1 LRP6 LRP6 ARHGEF4 ARHGEF4 TLE4 TLE4 APC APC DKK4 DKK4 GPC3 GPC3 NDP NDP TCN2 TCN2 DKK3 DKK3 CBY1 CBY1 KREMEN1 KREMEN1 M3YPY7_MUSPF M3YPY7_MUSPF PORCN PORCN DAAM2 DAAM2 PRICKLE3 PRICKLE3 VANGL2 VANGL2 CSNK1A1 CSNK1A1 M3YSA2_MUSPF M3YSA2_MUSPF DVL1 DVL1 NLK NLK LRP1B LRP1B TCN1 TCN1 CBLIF CBLIF AXIN2 AXIN2 WNT1 WNT1 WNT10B WNT10B DAB2 DAB2 BAMBI BAMBI FZD6 FZD6 HLF HLF GPATCH3 GPATCH3 LDLRAP1 LDLRAP1 WNT4 WNT4 AXIN1 AXIN1 WNT7B WNT7B WNT6 WNT6 WNT10A WNT10A WNT5A WNT5A PRICKLE2 PRICKLE2 WNT8B WNT8B DKK1 DKK1 SFRP5 SFRP5 FRAT2 FRAT2 M3Z062_MUSPF M3Z062_MUSPF WNT7A WNT7A WIF1 WIF1 WNT5B WNT5B MYO6 MYO6 SFRP4 SFRP4 RELN RELN AMER1 AMER1 FZD7 FZD7 FZD5 FZD5 FZD2 FZD2 FZD1 FZD1 M3Z6K8_MUSPF M3Z6K8_MUSPF LOC106003358 LOC106003358
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TLE1TLE family member 1, transcriptional corepressor. (771 aa)
PRICKLE1Prickle planar cell polarity protein 1. (832 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
M3XNJ2_MUSPFUncharacterized protein. (1362 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (778 aa)
LRP2LDL receptor related protein 2. (4699 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (451 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
VANGL1Vang-like protein. (524 aa)
LRP1LDL receptor related protein 1. (4544 aa)
TCF7L2Transcription factor 7 like 2. (514 aa)
M3XSG3_MUSPFCTNNB1_binding domain-containing protein. (169 aa)
PYGO1Pygopus family PHD finger 1. (419 aa)
FRZBFrizzled related protein. (325 aa)
DVL3Dishevelled segment polarity protein 3. (718 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2735 aa)
M3XU23_MUSPFUncharacterized protein. (370 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (425 aa)
M3XX61_MUSPFUncharacterized protein. (753 aa)
LRP5Uncharacterized protein. (1465 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
ATCAYATCAY kinesin light chain interacting caytaxin. (371 aa)
BCL9LBCL9 like. (1276 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
VLDLRVery low density lipoprotein receptor. (736 aa)
ZNF408Zinc finger protein 408. (722 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
LDLRLow density lipoprotein receptor. (856 aa)
M3Y377_MUSPFNTR domain-containing protein. (233 aa)
DAAM1Dishevelled associated activator of morphogenesis 1. (1069 aa)
LRP8LDL receptor related protein 8. (924 aa)
PYGO2Pygopus family PHD finger 2. (372 aa)
CDCP2CUB domain containing protein 2. (514 aa)
INVSInversin. (1079 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (951 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
TSPAN12Tetraspanin. (305 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
TESTestin; Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor (By similarity); Belongs to the prickle / espinas / testin family. (421 aa)
DAB1DAB adaptor protein 1. (523 aa)
CD320CD320 molecule. (258 aa)
LRP3LDL receptor related protein 3. (769 aa)
M3Y969_MUSPFOGFr_N domain-containing protein. (230 aa)
APC2APC regulator of WNT signaling pathway 2. (2481 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
TCF7L1Transcription factor 7 like 1. (490 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
LEF1Lymphoid enhancer binding factor 1. (400 aa)
DKK2Dickkopf WNT signaling pathway inhibitor 2. (259 aa)
RYKReceptor like tyrosine kinase. (478 aa)
SOSTSclerostin. (213 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
TCF7Transcription factor 7. (339 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
DVL2Dishevelled segment polarity protein 2. (734 aa)
LRPAP1LDL receptor related protein associated protein 1. (371 aa)
JUPJunction plakoglobin. (744 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (434 aa)
M3YJ32_MUSPFEGF-like domain-containing protein. (872 aa)
CUBNCubilin. (3619 aa)
CTNNB1Catenin beta 1. (781 aa)
LRP6LDL receptor related protein 6. (1462 aa)
ARHGEF4Rho guanine nucleotide exchange factor 4. (558 aa)
TLE4TLE family member 4, transcriptional corepressor. (711 aa)
APCAPC regulator of WNT signaling pathway. (2862 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (221 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
TCN2Transcobalamin 2. (430 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (348 aa)
CBY1Chibby family member 1, beta catenin antagonist. (127 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (444 aa)
M3YPY7_MUSPFUncharacterized protein. (386 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (461 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1092 aa)
PRICKLE3Prickle planar cell polarity protein 3. (706 aa)
VANGL2Vang-like protein. (503 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa)
M3YSA2_MUSPFUncharacterized protein. (301 aa)
DVL1Dishevelled segment polarity protein 1. (691 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
LRP1BLDL receptor related protein 1B. (3815 aa)
TCN1Transcobalamin 1. (434 aa)
CBLIFCobalamin binding intrinsic factor. (420 aa)
AXIN2Axin 2. (842 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
DAB2Disabled-like protein 2, mitogen-responsive phosphoprotein. (769 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (736 aa)
HLFHLF transcription factor, PAR bZIP family member. (295 aa)
GPATCH3G-patch domain containing 3. (519 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (309 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
AXIN1Axin 1. (862 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (383 aa)
PRICKLE2Prickle planar cell polarity protein 2. (844 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (270 aa)
SFRP5Secreted frizzled related protein 5. (317 aa)
FRAT2FRAT regulator of WNT signaling pathway 2. (191 aa)
M3Z062_MUSPFUncharacterized protein. (120 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
WIF1WNT inhibitory factor 1. (384 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (406 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1253 aa)
SFRP4Secreted frizzled related protein 4. (346 aa)
RELNReelin. (3458 aa)
AMER1APC membrane recruitment protein 1. (1134 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (602 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (550 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (642 aa)
M3Z6K8_MUSPFG_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family. (397 aa)
LOC106003358Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (544 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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