(11 nodes) Notch, and Notch ligand, N-terminal domain network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NOTCH2	Notch receptor 2. (2471 aa)
	M3XSG7_MUSPF	Uncharacterized protein. (233 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (602 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
	NOTCH4	Notch receptor 4. (1993 aa)
	NOTCH1	Notch receptor 1. (2119 aa)
	MFNG	Beta-1,3-N-acetylglucosaminyltransferase. (321 aa)
	NOTCH3	Notch receptor 3. (2305 aa)
	DLL3	Delta like canonical Notch ligand 3. (590 aa)
	M3Z2L9_MUSPF	Uncharacterized protein. (199 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLL1	DLL3	ENSMPUP00000006989	ENSMPUP00000017608	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta like canonical Notch ligand 3.	0.870
DLL1	DLL4	ENSMPUP00000006989	ENSMPUP00000008700	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.940
DLL1	JAG1	ENSMPUP00000006989	ENSMPUP00000006461	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.498
DLL1	M3Z2L9_MUSPF	ENSMPUP00000006989	ENSMPUP00000017831	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.591
DLL1	MFNG	ENSMPUP00000006989	ENSMPUP00000012658	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Beta-1,3-N-acetylglucosaminyltransferase.	0.588
DLL1	NOTCH1	ENSMPUP00000006989	ENSMPUP00000011233	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1.	0.992
DLL1	NOTCH2	ENSMPUP00000006989	ENSMPUP00000001388	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 2.	0.988
DLL1	NOTCH3	ENSMPUP00000006989	ENSMPUP00000015983	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 3.	0.986
DLL1	NOTCH4	ENSMPUP00000006989	ENSMPUP00000010033	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 4.	0.970
DLL3	DLL1	ENSMPUP00000017608	ENSMPUP00000006989	Delta like canonical Notch ligand 3.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.870
DLL3	DLL4	ENSMPUP00000017608	ENSMPUP00000008700	Delta like canonical Notch ligand 3.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.863
DLL3	M3Z2L9_MUSPF	ENSMPUP00000017608	ENSMPUP00000017831	Delta like canonical Notch ligand 3.	Uncharacterized protein.	0.469
DLL3	NOTCH1	ENSMPUP00000017608	ENSMPUP00000011233	Delta like canonical Notch ligand 3.	Notch receptor 1.	0.984
DLL3	NOTCH2	ENSMPUP00000017608	ENSMPUP00000001388	Delta like canonical Notch ligand 3.	Notch receptor 2.	0.972
DLL3	NOTCH3	ENSMPUP00000017608	ENSMPUP00000015983	Delta like canonical Notch ligand 3.	Notch receptor 3.	0.968
DLL3	NOTCH4	ENSMPUP00000017608	ENSMPUP00000010033	Delta like canonical Notch ligand 3.	Notch receptor 4.	0.973
DLL4	DLL1	ENSMPUP00000008700	ENSMPUP00000006989	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.940
DLL4	DLL3	ENSMPUP00000008700	ENSMPUP00000017608	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta like canonical Notch ligand 3.	0.863
DLL4	JAG1	ENSMPUP00000008700	ENSMPUP00000006461	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.447
DLL4	M3XSG7_MUSPF	ENSMPUP00000008700	ENSMPUP00000002017	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.435