STRINGSTRING
M3Y8T6_MUSPF M3Y8T6_MUSPF HBB HBB M3YFH4_MUSPF M3YFH4_MUSPF HBQ1 HBQ1 HBA_MUSPF HBA_MUSPF HBZ HBZ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M3Y8T6_MUSPFHaptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. (346 aa)
HBBHemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. (147 aa)
M3YFH4_MUSPFGLOBIN domain-containing protein; Belongs to the globin family. (147 aa)
HBQ1Hemoglobin subunit theta 1; Belongs to the globin family. (162 aa)
HBA_MUSPFHemoglobin subunit alpha-1/2; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family. (143 aa)
HBZHemoglobin subunit zeta; Belongs to the globin family. (142 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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