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PIKFYVE PIKFYVE MTMR6 MTMR6 SYNJ1 SYNJ1 MTMR9 MTMR9 IMPA1 IMPA1 PIP4K2C PIP4K2C ATXN2 ATXN2 INPP5A INPP5A ITPR3 ITPR3 PLCH1 PLCH1 PLCD1 PLCD1 INPP5F INPP5F IP6K3 IP6K3 PI4KA PI4KA ITPK1 ITPK1 PI4KB PI4KB PPIP5K2 PPIP5K2 PIP5K1A PIP5K1A IMPA2 IMPA2 IPPK IPPK ITPKB ITPKB SYNJ2 SYNJ2 PLCB4 PLCB4 PLCH2 PLCH2 M3YAI1_MUSPF M3YAI1_MUSPF OPN4 OPN4 PLCD3 PLCD3 ITPKA ITPKA PIP4P2 PIP4P2 PIP5K1B PIP5K1B TRPC7 TRPC7 FIG4 FIG4 PRKCG PRKCG PPIP5K1 PPIP5K1 VAC14 VAC14 ITPR2 ITPR2 IPMK IPMK IMPAD1 IMPAD1 INPP4A INPP4A PIK3C2G PIK3C2G INPP5E INPP5E MTM1 MTM1 MTMR1 MTMR1 PIK3C2B PIK3C2B PIP4K2A PIP4K2A PRKCB PRKCB MTMR2 MTMR2 INPP1 INPP1 M3YMU3_MUSPF M3YMU3_MUSPF ATXN2L ATXN2L INPP5J INPP5J PLCB3 PLCB3 MTMR3 MTMR3 PIK3C2A PIK3C2A IP6K1 IP6K1 INPP5K INPP5K PIP5KL1 PIP5KL1 IP6K2 IP6K2 INPP5B INPP5B PRKCA PRKCA PIP4K2B PIP4K2B MTMR12 MTMR12 M3YUZ9_MUSPF M3YUZ9_MUSPF MTMR4 MTMR4 SACM1L SACM1L ISYNA1 ISYNA1 INPP4B INPP4B PLCD4 PLCD4 PI4K2B PI4K2B PRKCD PRKCD MINPP1 MINPP1 ITPR1 ITPR1 M3Z019_MUSPF M3Z019_MUSPF MTMR14 MTMR14 TRPC3 TRPC3 USP53 USP53 OCRL OCRL ITPKC ITPKC MTMR7 MTMR7 PIP4P1 PIP4P1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2099 aa)
MTMR6Myotubularin related protein 6. (643 aa)
SYNJ1Synaptojanin 1. (1578 aa)
MTMR9Myotubularin related protein 9. (573 aa)
IMPA1Inositol-1-monophosphatase. (295 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa)
ATXN2Ataxin 2. (1066 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (364 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2609 aa)
PLCH1Phosphoinositide phospholipase C. (1684 aa)
PLCD1Phosphoinositide phospholipase C. (756 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1034 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (395 aa)
PI4KAPhosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2050 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (461 aa)
PI4KBPhosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (816 aa)
PPIP5K2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1243 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (565 aa)
IMPA2Inositol-1-monophosphatase. (288 aa)
IPPKInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (491 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (938 aa)
SYNJ2Synaptojanin 2. (1301 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PLCH2Phosphoinositide phospholipase C. (1130 aa)
M3YAI1_MUSPFANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (735 aa)
OPN4Opsin 4. (467 aa)
PLCD3Phosphoinositide phospholipase C. (780 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (540 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (807 aa)
FIG4FIG4 phosphoinositide 5-phosphatase. (907 aa)
PRKCGNon-specific serine/threonine protein kinase. (569 aa)
PPIP5K1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1517 aa)
VAC14VAC14 component of PIKFYVE complex. (784 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (430 aa)
IMPAD1Inositol monophosphatase domain containing 1. (294 aa)
INPP4AInositol polyphosphate-4-phosphatase type I A. (939 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1523 aa)
INPP5EInositol polyphosphate-5-phosphatase E. (642 aa)
MTM1Myotubularin 1. (603 aa)
MTMR1Myotubularin related protein 1. (605 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1637 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (368 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (577 aa)
MTMR2Myotubularin related protein 2. (643 aa)
INPP1Inositol polyphosphate-1-phosphatase. (402 aa)
M3YMU3_MUSPFMIR domain-containing protein. (78 aa)
ATXN2LAtaxin 2 like. (924 aa)
INPP5JInositol polyphosphate-5-phosphatase J. (1081 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
MTMR3Myotubularin related protein 3. (1211 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1702 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (462 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (473 aa)
PIP5KL1Phosphatidylinositol-4-phosphate 5-kinase like 1. (394 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (425 aa)
INPP5BInositol polyphosphate-5-phosphatase B. (794 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (363 aa)
MTMR12Myotubularin related protein 12. (720 aa)
M3YUZ9_MUSPFMyotubularin phosphatase domain-containing protein. (540 aa)
MTMR4Myotubularin related protein 4. (1146 aa)
SACM1LSAC1 like phosphatidylinositide phosphatase. (484 aa)
ISYNA1Inositol-3-phosphate synthase 1. (557 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (925 aa)
PLCD4Phosphoinositide phospholipase C. (798 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2 beta. (487 aa)
PRKCDProtein kinase C. (730 aa)
MINPP1Multiple inositol-polyphosphate phosphatase 1; Belongs to the histidine acid phosphatase family. (489 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2709 aa)
M3Z019_MUSPFPI3K/PI4K domain-containing protein. (479 aa)
MTMR14Myotubularin related protein 14. (649 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (866 aa)
USP53Ubiquitin specific peptidase 53. (1083 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (900 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (667 aa)
MTMR7Myotubularin related protein 7. (660 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (277 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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