(13 nodes) NuRD complex, and Interferon regulatory factor-1/2 network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDK2AP1	Cyclin dependent kinase 2 associated protein 1. (103 aa)
	MBD3	Methyl-CpG binding domain protein 3. (289 aa)
	GATAD2B	GATA zinc finger domain containing 2B. (597 aa)
	MTA1	Metastasis associated 1. (633 aa)
	CHD3	Chromodomain helicase DNA binding protein 3. (1708 aa)
	M3YBU5_MUSPF	CHDNT domain-containing protein. (120 aa)
	MTA3	Metastasis associated 1 family member 3. (621 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (469 aa)
	M3YGI0_MUSPF	MBD_C domain-containing protein. (69 aa)
	IRF1	Interferon regulatory factor. (322 aa)
	MTA2	Metastasis associated 1 family member 2. (622 aa)
	GATAD2A	GATA zinc finger domain containing 2A. (639 aa)
	CHD4	Uncharacterized protein. (1912 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDK2AP1	CHD3	ENSMPUP00000001651	ENSMPUP00000008791	Cyclin dependent kinase 2 associated protein 1.	Chromodomain helicase DNA binding protein 3.	0.700
CDK2AP1	CHD4	ENSMPUP00000001651	ENSMPUP00000016754	Cyclin dependent kinase 2 associated protein 1.	Uncharacterized protein.	0.637
CDK2AP1	GATAD2A	ENSMPUP00000001651	ENSMPUP00000015289	Cyclin dependent kinase 2 associated protein 1.	GATA zinc finger domain containing 2A.	0.888
CDK2AP1	GATAD2B	ENSMPUP00000001651	ENSMPUP00000008077	Cyclin dependent kinase 2 associated protein 1.	GATA zinc finger domain containing 2B.	0.753
CDK2AP1	HDAC2	ENSMPUP00000001651	ENSMPUP00000010193	Cyclin dependent kinase 2 associated protein 1.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.541
CDK2AP1	M3YBU5_MUSPF	ENSMPUP00000001651	ENSMPUP00000008802	Cyclin dependent kinase 2 associated protein 1.	CHDNT domain-containing protein.	0.700
CDK2AP1	M3YGI0_MUSPF	ENSMPUP00000001651	ENSMPUP00000010437	Cyclin dependent kinase 2 associated protein 1.	MBD_C domain-containing protein.	0.655
CDK2AP1	MBD3	ENSMPUP00000001651	ENSMPUP00000007987	Cyclin dependent kinase 2 associated protein 1.	Methyl-CpG binding domain protein 3.	0.655
CDK2AP1	MTA1	ENSMPUP00000001651	ENSMPUP00000008098	Cyclin dependent kinase 2 associated protein 1.	Metastasis associated 1.	0.575
CDK2AP1	MTA2	ENSMPUP00000001651	ENSMPUP00000013780	Cyclin dependent kinase 2 associated protein 1.	Metastasis associated 1 family member 2.	0.600
CDK2AP1	MTA3	ENSMPUP00000001651	ENSMPUP00000008823	Cyclin dependent kinase 2 associated protein 1.	Metastasis associated 1 family member 3.	0.637
CHD3	CDK2AP1	ENSMPUP00000008791	ENSMPUP00000001651	Chromodomain helicase DNA binding protein 3.	Cyclin dependent kinase 2 associated protein 1.	0.700
CHD3	CHD4	ENSMPUP00000008791	ENSMPUP00000016754	Chromodomain helicase DNA binding protein 3.	Uncharacterized protein.	0.864
CHD3	GATAD2A	ENSMPUP00000008791	ENSMPUP00000015289	Chromodomain helicase DNA binding protein 3.	GATA zinc finger domain containing 2A.	0.914
CHD3	GATAD2B	ENSMPUP00000008791	ENSMPUP00000008077	Chromodomain helicase DNA binding protein 3.	GATA zinc finger domain containing 2B.	0.860
CHD3	HDAC2	ENSMPUP00000008791	ENSMPUP00000010193	Chromodomain helicase DNA binding protein 3.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.902
CHD3	M3YBU5_MUSPF	ENSMPUP00000008791	ENSMPUP00000008802	Chromodomain helicase DNA binding protein 3.	CHDNT domain-containing protein.	0.878
CHD3	M3YGI0_MUSPF	ENSMPUP00000008791	ENSMPUP00000010437	Chromodomain helicase DNA binding protein 3.	MBD_C domain-containing protein.	0.830
CHD3	MBD3	ENSMPUP00000008791	ENSMPUP00000007987	Chromodomain helicase DNA binding protein 3.	Methyl-CpG binding domain protein 3.	0.843
CHD3	MTA1	ENSMPUP00000008791	ENSMPUP00000008098	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1.	0.832