(45 nodes) Mixed, incl. Negative regulation of activity of TFAP2 (AP-2) family transcription factors, and Tube lumen cavitation network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TFAP2A	Transcription factor AP-2 alpha. (384 aa)
	EDA	Ectodysplasin A; Belongs to the tumor necrosis factor family. (257 aa)
	BARX1	BARX homeobox 1. (196 aa)
	M3XZJ3_MUSPF	Uncharacterized protein. (140 aa)
	CLPTM1	CLPTM1 regulator of GABA type A receptor forward trafficking. (645 aa)
	ETV2	ETS variant 2. (344 aa)
	TFAP2C	Transcription factor AP-2 gamma. (450 aa)
	KCTD15	Potassium channel tetramerization domain containing 15. (283 aa)
	CBFA2T3	CBFA2/RUNX1 partner transcriptional co-repressor 3. (630 aa)
	MSX1	Msh homeobox 1. (303 aa)
	BANP	BTG3 associated nuclear protein. (503 aa)
	PITX2	Homeobox protein. (317 aa)
	FOXC2	Forkhead box C2. (370 aa)
	FOXF1	Forkhead box F1. (321 aa)
	TFAP2B	Transcription factor AP-2 beta. (476 aa)
	TFAP2D	Transcription factor AP-2 delta. (452 aa)
	ARID3A	AT-rich interaction domain 3A. (597 aa)
	LTBP2	Latent transforming growth factor beta binding protein 2. (1818 aa)
	PRSS57	Serine protease 57; Belongs to the peptidase S1 family. (287 aa)
	M3YE76_MUSPF	Homeobox domain-containing protein. (208 aa)
	WWOX	WW domain containing oxidoreductase. (462 aa)
	EDAR	Ectodysplasin A receptor. (459 aa)
	SNAI2	Snail family transcriptional repressor 2. (268 aa)
	MARCHF3	Membrane associated ring-CH-type finger 3. (253 aa)
	M3YM96_MUSPF	HIG1 domain-containing protein. (106 aa)
	TBX22	T-box transcription factor 22. (522 aa)
	MSX2	Msh homeobox 2. (267 aa)
	SH3PXD2B	SH3 and PX domains 2B. (938 aa)
	EDARADD	EDAR associated death domain. (193 aa)
	TMEM69	Transmembrane protein 69. (296 aa)
	MEOX2	Mesenchyme homeobox 2. (303 aa)
	MILR1	Mast cell immunoglobulin like receptor 1. (367 aa)
	TFAP2E	Transcription factor AP-2 epsilon. (433 aa)
	OSR2	Odd-skipped related transciption factor 2. (276 aa)
	FLYWCH1	Uncharacterized protein. (704 aa)
	M3YVU1_MUSPF	Uncharacterized protein. (320 aa)
	AKR7A2	Aldo-keto reductase family 7 member A2. (344 aa)
	PAX9	Paired box 9. (362 aa)
	M3Z133_MUSPF	Uncharacterized protein. (709 aa)
	M3Z134_MUSPF	Uncharacterized protein. (551 aa)
	ROMO1	Reactive oxygen species modulator 1. (79 aa)
	MYO1G	Myosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa)
	FOXC1	Forkhead box C1. (552 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
	KCTD4	Potassium channel tetramerization domain containing 4. (259 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKR7A2	ETV2	ENSMPUP00000016062	ENSMPUP00000006228	Aldo-keto reductase family 7 member A2.	ETS variant 2.	0.457
AKR7A2	TMEM69	ENSMPUP00000016062	ENSMPUP00000012940	Aldo-keto reductase family 7 member A2.	Transmembrane protein 69.	0.615
ARID3A	BANP	ENSMPUP00000009224	ENSMPUP00000008182	AT-rich interaction domain 3A.	BTG3 associated nuclear protein.	0.526
BANP	ARID3A	ENSMPUP00000008182	ENSMPUP00000009224	BTG3 associated nuclear protein.	AT-rich interaction domain 3A.	0.526
BANP	WWOX	ENSMPUP00000008182	ENSMPUP00000009729	BTG3 associated nuclear protein.	WW domain containing oxidoreductase.	0.473
BARX1	M3Z133_MUSPF	ENSMPUP00000004357	ENSMPUP00000017295	BARX homeobox 1.	Uncharacterized protein.	0.454
BARX1	M3Z134_MUSPF	ENSMPUP00000004357	ENSMPUP00000017296	BARX homeobox 1.	Uncharacterized protein.	0.454
BARX1	MSX2	ENSMPUP00000004357	ENSMPUP00000012579	BARX homeobox 1.	Msh homeobox 2.	0.475
BARX1	OSR2	ENSMPUP00000004357	ENSMPUP00000015137	BARX homeobox 1.	Odd-skipped related transciption factor 2.	0.679
BARX1	PAX9	ENSMPUP00000004357	ENSMPUP00000016155	BARX homeobox 1.	Paired box 9.	0.493
BARX1	TBX22	ENSMPUP00000004357	ENSMPUP00000012525	BARX homeobox 1.	T-box transcription factor 22.	0.537
CBFA2T3	M3YM96_MUSPF	ENSMPUP00000007559	ENSMPUP00000012453	CBFA2/RUNX1 partner transcriptional co-repressor 3.	HIG1 domain-containing protein.	0.620
CBFA2T3	MILR1	ENSMPUP00000007559	ENSMPUP00000014641	CBFA2/RUNX1 partner transcriptional co-repressor 3.	Mast cell immunoglobulin like receptor 1.	0.639
CBFA2T3	PRSS57	ENSMPUP00000007559	ENSMPUP00000009588	CBFA2/RUNX1 partner transcriptional co-repressor 3.	Serine protease 57; Belongs to the peptidase S1 family.	0.627
CITED2	TFAP2A	ENSMPUP00000018764	ENSMPUP00000000595	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Transcription factor AP-2 alpha.	0.528
CITED2	TFAP2B	ENSMPUP00000018764	ENSMPUP00000009008	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Transcription factor AP-2 beta.	0.455
CITED2	TFAP2C	ENSMPUP00000018764	ENSMPUP00000006332	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Transcription factor AP-2 gamma.	0.455
CITED2	TFAP2D	ENSMPUP00000018764	ENSMPUP00000009019	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Transcription factor AP-2 delta.	0.610
CITED2	TFAP2E	ENSMPUP00000018764	ENSMPUP00000014783	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Transcription factor AP-2 epsilon.	0.455
CLPTM1	TBX22	ENSMPUP00000006096	ENSMPUP00000012525	CLPTM1 regulator of GABA type A receptor forward trafficking.	T-box transcription factor 22.	0.526