(6 nodes) Mixed, incl. Guanine nucleotide-binding protein, beta subunit, and Mu-type opioid receptor binding network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (447 aa)
	GNAO1	G protein subunit alpha o1. (354 aa)
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (76 aa)
	GNB2	G protein subunit beta 2. (340 aa)
	GNB3	G protein subunit beta 3. (344 aa)
	APLNR	Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APLNR	GNAO1	ENSMPUP00000018728	ENSMPUP00000003408	Apelin receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha o1.	0.641
APLNR	GNB2	ENSMPUP00000018728	ENSMPUP00000015595	Apelin receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 2.	0.973
APLNR	GNB3	ENSMPUP00000018728	ENSMPUP00000016678	Apelin receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 3.	0.966
APLNR	GNG3	ENSMPUP00000018728	ENSMPUP00000013607	Apelin receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.939
DRD3	GNAO1	ENSMPUP00000000275	ENSMPUP00000003408	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha o1.	0.935
DRD3	GNB2	ENSMPUP00000000275	ENSMPUP00000015595	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 2.	0.973
DRD3	GNB3	ENSMPUP00000000275	ENSMPUP00000016678	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 3.	0.956
DRD3	GNG3	ENSMPUP00000000275	ENSMPUP00000013607	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.931
GNAO1	APLNR	ENSMPUP00000003408	ENSMPUP00000018728	G protein subunit alpha o1.	Apelin receptor; Belongs to the G-protein coupled receptor 1 family.	0.641
GNAO1	DRD3	ENSMPUP00000003408	ENSMPUP00000000275	G protein subunit alpha o1.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.935
GNAO1	GNB2	ENSMPUP00000003408	ENSMPUP00000015595	G protein subunit alpha o1.	G protein subunit beta 2.	0.989
GNAO1	GNB3	ENSMPUP00000003408	ENSMPUP00000016678	G protein subunit alpha o1.	G protein subunit beta 3.	0.978
GNAO1	GNG3	ENSMPUP00000003408	ENSMPUP00000013607	G protein subunit alpha o1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.959
GNB2	APLNR	ENSMPUP00000015595	ENSMPUP00000018728	G protein subunit beta 2.	Apelin receptor; Belongs to the G-protein coupled receptor 1 family.	0.973
GNB2	DRD3	ENSMPUP00000015595	ENSMPUP00000000275	G protein subunit beta 2.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.973
GNB2	GNAO1	ENSMPUP00000015595	ENSMPUP00000003408	G protein subunit beta 2.	G protein subunit alpha o1.	0.989
GNB2	GNB3	ENSMPUP00000015595	ENSMPUP00000016678	G protein subunit beta 2.	G protein subunit beta 3.	0.509
GNB2	GNG3	ENSMPUP00000015595	ENSMPUP00000013607	G protein subunit beta 2.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.899
GNB3	APLNR	ENSMPUP00000016678	ENSMPUP00000018728	G protein subunit beta 3.	Apelin receptor; Belongs to the G-protein coupled receptor 1 family.	0.966
GNB3	DRD3	ENSMPUP00000016678	ENSMPUP00000000275	G protein subunit beta 3.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.956