(41 nodes) Small-subunit processome, and Positive regulation of rRNA processing network (Mustela putorius)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NOP58	NOP58 ribonucleoprotein. (539 aa)
	PMEL	Premelanosome protein. (656 aa)
	WDR3	WD repeat domain 3. (942 aa)
	WDR46	WD_REPEATS_REGION domain-containing protein. (586 aa)
	NOC4L	Nucleolar complex associated 4 homolog. (438 aa)
	NOL6	Nucleolar protein 6. (1143 aa)
	DNTTIP2	Deoxynucleotidyltransferase terminal interacting protein 2. (772 aa)
	RCL1	RNA terminal phosphate cyclase like 1. (373 aa)
	UTP15	UTP15 small subunit processome component. (518 aa)
	NGDN	Neuroguidin. (290 aa)
	UTP4	UTP4 small subunit processome component. (748 aa)
	M3YA56_MUSPF	NUC153 domain-containing protein. (296 aa)
	NOP56	NOP56 ribonucleoprotein. (597 aa)
	FCF1	PINc domain-containing protein. (198 aa)
	M3YEV4_MUSPF	Uncharacterized protein. (799 aa)
	M3YHB0_MUSPF	WD_REPEATS_REGION domain-containing protein. (610 aa)
	NOP14	NOP14 nucleolar protein. (863 aa)
	MPHOSPH10	U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (680 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1026 aa)
	UTP20	UTP20 small subunit processome component. (2786 aa)
	RRP9	Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein. (473 aa)
	WDR75	WD repeat domain 75. (807 aa)
	WDR36	WD repeat domain 36. (895 aa)
	HEATR1	HEAT repeat containing 1. (2141 aa)
	FBLL1	Fibrillarin like 1. (266 aa)
	IMP4	IMP U3 small nucleolar ribonucleoprotein 4. (291 aa)
	UTP11	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (253 aa)
	UTP6	UTP6 small subunit processome component. (596 aa)
	AATF	Apoptosis antagonizing transcription factor. (565 aa)
	TBL3	Transducin beta like 3. (804 aa)
	UTP18	UTP18 small subunit processome component. (555 aa)
	RRP7A	Ribosomal RNA processing 7 homolog A. (280 aa)
	SNU13	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (127 aa)
	EMG1	EMG1 N1-specific pseudouridine methyltransferase. (244 aa)
	PDCD11	Programmed cell death 11. (1870 aa)
	BMS1	BMS1 ribosome biogenesis factor. (1279 aa)
	M3Z164_MUSPF	Uncharacterized protein. (772 aa)
	KRR1	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (381 aa)
	WDR43	WD repeat domain 43. (682 aa)
	UTP3	UTP3 small subunit processome component. (474 aa)
	IMP3	IMP U3 small nucleolar ribonucleoprotein 3. (184 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AATF	BMS1	ENSMPUP00000014946	ENSMPUP00000017167	Apoptosis antagonizing transcription factor.	BMS1 ribosome biogenesis factor.	0.991
AATF	DNTTIP2	ENSMPUP00000014946	ENSMPUP00000003967	Apoptosis antagonizing transcription factor.	Deoxynucleotidyltransferase terminal interacting protein 2.	0.984
AATF	EMG1	ENSMPUP00000014946	ENSMPUP00000016658	Apoptosis antagonizing transcription factor.	EMG1 N1-specific pseudouridine methyltransferase.	0.984
AATF	FBLL1	ENSMPUP00000014946	ENSMPUP00000012946	Apoptosis antagonizing transcription factor.	Fibrillarin like 1.	0.968
AATF	FCF1	ENSMPUP00000014946	ENSMPUP00000009247	Apoptosis antagonizing transcription factor.	PINc domain-containing protein.	0.980
AATF	HEATR1	ENSMPUP00000014946	ENSMPUP00000012653	Apoptosis antagonizing transcription factor.	HEAT repeat containing 1.	0.981
AATF	IMP3	ENSMPUP00000014946	ENSMPUP00000020013	Apoptosis antagonizing transcription factor.	IMP U3 small nucleolar ribonucleoprotein 3.	0.973
AATF	IMP4	ENSMPUP00000014946	ENSMPUP00000013159	Apoptosis antagonizing transcription factor.	IMP U3 small nucleolar ribonucleoprotein 4.	0.988
AATF	KRR1	ENSMPUP00000014946	ENSMPUP00000017365	Apoptosis antagonizing transcription factor.	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.	0.983
AATF	M3YA56_MUSPF	ENSMPUP00000014946	ENSMPUP00000008213	Apoptosis antagonizing transcription factor.	NUC153 domain-containing protein.	0.952
AATF	M3YEV4_MUSPF	ENSMPUP00000014946	ENSMPUP00000009861	Apoptosis antagonizing transcription factor.	Uncharacterized protein.	0.983
AATF	M3YHB0_MUSPF	ENSMPUP00000014946	ENSMPUP00000010717	Apoptosis antagonizing transcription factor.	WD_REPEATS_REGION domain-containing protein.	0.948
AATF	M3Z164_MUSPF	ENSMPUP00000014946	ENSMPUP00000017326	Apoptosis antagonizing transcription factor.	Uncharacterized protein.	0.995
AATF	MPHOSPH10	ENSMPUP00000014946	ENSMPUP00000010999	Apoptosis antagonizing transcription factor.	U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family.	0.982
AATF	NAT10	ENSMPUP00000014946	ENSMPUP00000011544	Apoptosis antagonizing transcription factor.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.995
AATF	NGDN	ENSMPUP00000014946	ENSMPUP00000006384	Apoptosis antagonizing transcription factor.	Neuroguidin.	0.992
AATF	NOC4L	ENSMPUP00000014946	ENSMPUP00000002389	Apoptosis antagonizing transcription factor.	Nucleolar complex associated 4 homolog.	0.974
AATF	NOL6	ENSMPUP00000014946	ENSMPUP00000003891	Apoptosis antagonizing transcription factor.	Nucleolar protein 6.	0.987
AATF	NOP14	ENSMPUP00000014946	ENSMPUP00000010812	Apoptosis antagonizing transcription factor.	NOP14 nucleolar protein.	0.994
AATF	NOP56	ENSMPUP00000014946	ENSMPUP00000009042	Apoptosis antagonizing transcription factor.	NOP56 ribonucleoprotein.	0.982