(13 nodes) Mixed, incl. GABA synthesis, and D-Glutamine and D-glutamate metabolism network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GAD1	Glutamate decarboxylase 1. (594 aa)
	GLS2	Glutaminase 2. (602 aa)
	ALDH5A1	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (434 aa)
	L2HGDH	L-2-hydroxyglutarate dehydrogenase. (463 aa)
	M3YC07_MUSPF	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (490 aa)
	GLUL	Glutamine synthetase. (414 aa)
	GAD2	Glutamate decarboxylase 2. (585 aa)
	GLS	Glutaminase. (541 aa)
	ABAT	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (518 aa)
	M3YXM9_MUSPF	IF rod domain-containing protein; Belongs to the aldehyde dehydrogenase family. (1435 aa)
	M3YYI0_MUSPF	Uncharacterized protein. (126 aa)
	M3YYI2_MUSPF	Uncharacterized protein. (111 aa)
	ALDH18A1	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (795 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABAT	ALDH18A1	ENSMPUP00000014632	ENSMPUP00000017005	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.840
ABAT	ALDH5A1	ENSMPUP00000014632	ENSMPUP00000004621	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.985
ABAT	GAD1	ENSMPUP00000014632	ENSMPUP00000000805	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase 1.	0.877
ABAT	GAD2	ENSMPUP00000014632	ENSMPUP00000012075	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase 2.	0.951
ABAT	GLUL	ENSMPUP00000014632	ENSMPUP00000011419	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamine synthetase.	0.431
ABAT	L2HGDH	ENSMPUP00000014632	ENSMPUP00000004999	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	L-2-hydroxyglutarate dehydrogenase.	0.426
ABAT	M3YC07_MUSPF	ENSMPUP00000014632	ENSMPUP00000008864	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.832
ABAT	M3YXM9_MUSPF	ENSMPUP00000014632	ENSMPUP00000016089	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	IF rod domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.552
ABAT	M3YYI0_MUSPF	ENSMPUP00000014632	ENSMPUP00000016390	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Uncharacterized protein.	0.877
ABAT	M3YYI2_MUSPF	ENSMPUP00000014632	ENSMPUP00000016392	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Uncharacterized protein.	0.877
ALDH18A1	ABAT	ENSMPUP00000017005	ENSMPUP00000014632	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.840
ALDH18A1	ALDH5A1	ENSMPUP00000017005	ENSMPUP00000004621	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.943
ALDH18A1	GAD1	ENSMPUP00000017005	ENSMPUP00000000805	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutamate decarboxylase 1.	0.841
ALDH18A1	GAD2	ENSMPUP00000017005	ENSMPUP00000012075	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutamate decarboxylase 2.	0.937
ALDH18A1	GLS	ENSMPUP00000017005	ENSMPUP00000012358	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutaminase.	0.931
ALDH18A1	GLS2	ENSMPUP00000017005	ENSMPUP00000001463	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutaminase 2.	0.930
ALDH18A1	GLUL	ENSMPUP00000017005	ENSMPUP00000011419	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutamine synthetase.	0.970
ALDH18A1	L2HGDH	ENSMPUP00000017005	ENSMPUP00000004999	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	L-2-hydroxyglutarate dehydrogenase.	0.411
ALDH18A1	M3YC07_MUSPF	ENSMPUP00000017005	ENSMPUP00000008864	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.972
ALDH18A1	M3YXM9_MUSPF	ENSMPUP00000017005	ENSMPUP00000016089	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	IF rod domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.976