STRINGSTRING
NUP62 NUP62 CHAMP1 CHAMP1 RRS1 RRS1 HASPIN HASPIN LATS1 LATS1 DDX11 DDX11 RAD21L1 RAD21L1 MIS12 MIS12 MAD1L1 MAD1L1 KIF3B KIF3B MAPRE1 MAPRE1 DSN1 DSN1 KIF11 KIF11 LOC101678990 LOC101678990 NCAPD2 NCAPD2 ZWINT ZWINT PHB2 PHB2 CUL3 CUL3 VPS4B VPS4B SMC1B SMC1B AKAP8L AKAP8L NEK2 NEK2 PRC1 PRC1 STAG3 STAG3 GPN2 GPN2 NUDC NUDC MAU2 MAU2 RAD51C RAD51C KPNB1 KPNB1 NIPBL NIPBL CENPK CENPK ZNF207 ZNF207 CDCA8 CDCA8 TOP2A TOP2A RACGAP1 RACGAP1 SPAG5 SPAG5 INCENP INCENP EML3 EML3 KIF2C KIF2C NSL1 NSL1 HORMAD2 HORMAD2 SGO1 SGO1 SPDL1 SPDL1 KIF22 KIF22 M3YLP8_MUSPF M3YLP8_MUSPF MRE11 MRE11 PLK1 PLK1 TOP2B TOP2B ZCWPW2 ZCWPW2 CHMP6 CHMP6 M3YJJ3_MUSPF M3YJJ3_MUSPF M3YJI5_MUSPF M3YJI5_MUSPF KIF18A KIF18A CHMP2B CHMP2B KIF14 KIF14 PIBF1 PIBF1 TUBG2 TUBG2 BECN1 BECN1 NCAPG2 NCAPG2 SMC1A SMC1A CDC23 CDC23 STAG1 STAG1 M3YD28_MUSPF M3YD28_MUSPF M3YCZ1_MUSPF M3YCZ1_MUSPF CENPE CENPE NCAPD3 NCAPD3 NCAPH NCAPH KIF18B KIF18B EML4 EML4 M3YBR7_MUSPF M3YBR7_MUSPF INO80 INO80 KNSTRN KNSTRN M3YAG0_MUSPF M3YAG0_MUSPF CHMP2A CHMP2A AURKB AURKB SGO2 SGO2 M3Y8U7_MUSPF M3Y8U7_MUSPF WRAP73 WRAP73 FBXW7 FBXW7 ANKRD53 ANKRD53 M3Y7C1_MUSPF M3Y7C1_MUSPF CHMP1A CHMP1A NAA50 NAA50 RAB11A RAB11A ESCO2 ESCO2 RAD21 RAD21 DSCC1 DSCC1 M3XQE0_MUSPF M3XQE0_MUSPF STAG2 STAG2 RB1 RB1 CENPC CENPC M3XRQ6_MUSPF M3XRQ6_MUSPF CHMP4C CHMP4C DCTN2 DCTN2 KNTC1 KNTC1 PDS5B PDS5B NCAPH2 NCAPH2 SMC3 SMC3 M3XSL4_MUSPF M3XSL4_MUSPF GPN3 GPN3 NCAPG NCAPG KIFC1 KIFC1 BUB3 BUB3 SMC4 SMC4 MCMBP MCMBP PSRC1 PSRC1 CHMP7 CHMP7 POGZ POGZ KLHL22 KLHL22 M3XXC5_MUSPF M3XXC5_MUSPF NUF2 NUF2 ZW10 ZW10 RAN RAN CHMP5 CHMP5 KIF4A KIF4A SEH1L SEH1L HORMAD1 HORMAD1 KATNB1 KATNB1 FBXW9 FBXW9 DIS3L2 DIS3L2 M3Y1V5_MUSPF M3Y1V5_MUSPF NDC80 NDC80 ESCO1 ESCO1 CHMP4A CHMP4A REC8 REC8 ESPL1 ESPL1 PDS5A PDS5A PHF13 PHF13 SMC2 SMC2 DERPC DERPC RAB11B RAB11B M3Z7E4_MUSPF M3Z7E4_MUSPF MAP10 MAP10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NUP62Nucleoporin 62. (527 aa)
CHAMP1Chromosome alignment maintaining phosphoprotein 1. (814 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (371 aa)
HASPINHistone H3 associated protein kinase. (767 aa)
LATS1Large tumor suppressor kinase 1. (1127 aa)
DDX11DEAD/H-box helicase 11. (906 aa)
RAD21L1RAD21 cohesin complex component like 1. (553 aa)
MIS12MIS12 kinetochore complex component. (206 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (737 aa)
KIF3BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
DSN1DSN1 component of MIS12 kinetochore complex. (354 aa)
KIF11Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1056 aa)
LOC101678990Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (967 aa)
NCAPD2Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1399 aa)
ZWINTZW10 interacting kinetochore protein. (286 aa)
PHB2Prohibitin. (299 aa)
CUL3Cullin 3; Belongs to the cullin family. (746 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (422 aa)
SMC1BStructural maintenance of chromosomes protein. (1207 aa)
AKAP8LA-kinase anchoring protein 8 like; Belongs to the AKAP95 family. (708 aa)
NEK2NIMA related kinase 2. (444 aa)
PRC1Protein regulator of cytokinesis 1. (563 aa)
STAG3Stromal antigen 3. (1249 aa)
GPN2GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (320 aa)
NUDCNuclear distribution C, dynein complex regulator. (332 aa)
MAU2MAU2 sister chromatid cohesion factor. (613 aa)
RAD51CRAD51 paralog C. (371 aa)
KPNB1Karyopherin subunit beta 1. (877 aa)
NIPBLNipped-B protein. (2803 aa)
CENPKCentromere protein K. (273 aa)
ZNF207Zinc finger protein 207. (534 aa)
CDCA8Cell division cycle associated 8. (280 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1511 aa)
RACGAP1Rac GTPase activating protein 1. (631 aa)
SPAG5Sperm associated antigen 5. (1197 aa)
INCENPInner centromere protein. (890 aa)
EML3EMAP like 3. (897 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (723 aa)
NSL1NSL1, MIND kinetochore complex component,-like protein. (279 aa)
HORMAD2HORMA domain containing 2. (306 aa)
SGO1Shugoshin 1. (532 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (603 aa)
KIF22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (660 aa)
M3YLP8_MUSPFUncharacterized protein. (433 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (707 aa)
PLK1Serine/threonine-protein kinase PLK. (542 aa)
TOP2BDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1542 aa)
ZCWPW2Uncharacterized protein. (360 aa)
CHMP6Charged multivesicular body protein 6. (199 aa)
M3YJJ3_MUSPFUncharacterized protein. (169 aa)
M3YJI5_MUSPFUncharacterized protein. (255 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (897 aa)
CHMP2BCharged multivesicular body protein 2B. (213 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1662 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (757 aa)
TUBG2Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (451 aa)
BECN1Beclin 1. (448 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1138 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
CDC23Cell division cycle 23. (590 aa)
STAG1Stromal antigen 1. (1258 aa)
M3YD28_MUSPFUncharacterized protein. (1086 aa)
M3YCZ1_MUSPFUncharacterized protein. (223 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2814 aa)
NCAPD3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1482 aa)
NCAPHCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (675 aa)
KIF18BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (866 aa)
EML4EMAP like 4. (992 aa)
M3YBR7_MUSPFUncharacterized protein. (441 aa)
INO80INO80 complex ATPase subunit. (1561 aa)
KNSTRNKinetochore localized astrin (SPAG5) binding protein. (316 aa)
M3YAG0_MUSPFBUB1 N-terminal domain-containing protein. (1062 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
SGO2Shugoshin 2. (1194 aa)
M3Y8U7_MUSPFCDT1 domain-containing protein. (347 aa)
WRAP73WD repeat containing, antisense to TP73. (460 aa)
FBXW7F-box and WD repeat domain containing 7. (708 aa)
ANKRD53Ankyrin repeat domain 53. (437 aa)
M3Y7C1_MUSPFUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
CHMP1ACharged multivesicular body protein 1A. (196 aa)
NAA50N(alpha)-acetyltransferase 50, NatE catalytic subunit. (169 aa)
RAB11ARAB11A, member RAS oncogene family. (216 aa)
ESCO2Establishment of sister chromatid cohesion N-acetyltransferase 2. (613 aa)
RAD21RAD21 cohesin complex component. (631 aa)
DSCC1DNA replication and sister chromatid cohesion 1. (493 aa)
M3XQE0_MUSPFSCD domain-containing protein. (1107 aa)
STAG2Stromal antigen 2. (1268 aa)
RB1RB transcriptional corepressor 1. (948 aa)
CENPCCentromere protein C. (947 aa)
M3XRQ6_MUSPFG-patch domain-containing protein. (319 aa)
CHMP4CCharged multivesicular body protein 4C. (237 aa)
DCTN2Dynactin subunit 2. (422 aa)
KNTC1Kinetochore associated 1. (2207 aa)
PDS5BPDS5 cohesin associated factor B. (1448 aa)
NCAPH2Non-SMC condensin II complex subunit H2. (555 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
M3XSL4_MUSPFUncharacterized protein. (443 aa)
GPN3GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (284 aa)
NCAPGNon-SMC condensin I complex subunit G. (1014 aa)
KIFC1Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (674 aa)
BUB3BUB3 mitotic checkpoint protein. (328 aa)
SMC4Structural maintenance of chromosomes protein. (1288 aa)
MCMBPMinichromosome maintenance complex binding protein. (570 aa)
PSRC1Proline and serine rich coiled-coil 1. (327 aa)
CHMP7Charged multivesicular body protein 7. (398 aa)
POGZPogo transposable element derived with ZNF domain. (1414 aa)
KLHL22Kelch like family member 22. (634 aa)
M3XXC5_MUSPFNsp1_C domain-containing protein. (267 aa)
NUF2NUF2, NDC80 kinetochore complex component,-like protein. (464 aa)
ZW10Zw10 kinetochore protein. (779 aa)
RANGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (214 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
KIF4AKinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1239 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (421 aa)
HORMAD1HORMA domain containing 1. (396 aa)
KATNB1Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (655 aa)
FBXW9F-box and WD repeat domain containing 9. (459 aa)
DIS3L2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (884 aa)
M3Y1V5_MUSPFHistone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (415 aa)
NDC80NDC80 kinetochore complex component. (642 aa)
ESCO1Establishment of sister chromatid cohesion N-acetyltransferase 1. (845 aa)
CHMP4ACharged multivesicular body protein 4A. (266 aa)
REC8REC8 meiotic recombination protein. (593 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2111 aa)
PDS5APDS5 cohesin associated factor A. (1337 aa)
PHF13PHD finger protein 13. (346 aa)
SMC2Structural maintenance of chromosomes protein. (1191 aa)
DERPCDERPC proline and glycine rich nuclear protein. (514 aa)
RAB11BRAB11B, member RAS oncogene family. (218 aa)
M3Z7E4_MUSPFUncharacterized protein. (1085 aa)
MAP10Microtubule associated protein 10. (848 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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