36 items (Mustela putorius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPRD2	Regulation of nuclear pre-mRNA domain containing 2. (1465 aa)
	RPRD1B	Regulation of nuclear pre-mRNA domain containing 1B. (326 aa)
	PAF1	PAF1 homolog, Paf1/RNA polymerase II complex component. (554 aa)
	PCIF1	PDX1 C-terminal inhibiting factor 1. (702 aa)
	IWS1	Interacts with SUPT6H, CTD assembly factor 1. (846 aa)
	M3YWJ0_MUSPF	MYND-type domain-containing protein. (190 aa)
	SMYD3	SET and MYND domain containing 3. (239 aa)
	HNRNPU	Heterogeneous nuclear ribonucleoprotein U. (592 aa)
	SUPT4H1	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (120 aa)
	WAC	WW domain containing adaptor with coiled-coil. (601 aa)
	RECQL5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (986 aa)
	FBF1	Fas binding factor 1. (1160 aa)
	M3YPV3_MUSPF	Uncharacterized protein. (405 aa)
	CTR9	CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
	M3YLL3_MUSPF	SET domain-containing protein. (374 aa)
	DHX9	DExH-box helicase 9. (1200 aa)
	ELP4	Elongator acetyltransferase complex subunit 4. (423 aa)
	ERCC5	ERCC excision repair 5, endonuclease. (1193 aa)
	UVSSA	UV stimulated scaffold protein A. (706 aa)
	RTF1	RTF1 homolog, Paf1/RNA polymerase II complex component. (710 aa)
	PCF11	PCF11 cleavage and polyadenylation factor subunit. (1555 aa)
	URI1	URI1 prefoldin like chaperone. (459 aa)
	G9K828_MUSPF	Senescence downregulated leo1-like protein. (115 aa)
	LEO1	LEO1 homolog, Paf1/RNA polymerase II complex component. (664 aa)
	RTRAF	RNA transcription, translation and transport factor. (244 aa)
	ELOF1	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (83 aa)
	GTF2B	General transcription factor IIB. (316 aa)
	CDC73	Cell division cycle 73. (531 aa)
	CCAR2	Cell cycle and apoptosis regulator 2. (925 aa)
	SCAF1	SR-related CTD associated factor 1. (1235 aa)
	SCAF8	SR-related CTD associated factor 8. (1290 aa)
	AGO2	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (852 aa)
	RPRD1A	Regulation of nuclear pre-mRNA domain containing 1A. (312 aa)
	ELP2	Elongator acetyltransferase complex subunit 2. (826 aa)
	SCAF4	SR-related CTD associated factor 4. (1151 aa)
	WDR43	WD repeat domain 43. (682 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO2	CTR9	ENSMPUP00000001914	ENSMPUP00000012777	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	CTR9 homolog, Paf1/RNA polymerase II complex component.	0.417
AGO2	DHX9	ENSMPUP00000001914	ENSMPUP00000011453	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	DExH-box helicase 9.	0.800
CDC73	CTR9	ENSMPUP00000004608	ENSMPUP00000012777	Cell division cycle 73.	CTR9 homolog, Paf1/RNA polymerase II complex component.	0.999
CDC73	ELOF1	ENSMPUP00000004608	ENSMPUP00000004868	Cell division cycle 73.	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family.	0.834
CDC73	G9K828_MUSPF	ENSMPUP00000004608	ENSMPUP00000007605	Cell division cycle 73.	Senescence downregulated leo1-like protein.	0.999
CDC73	IWS1	ENSMPUP00000004608	ENSMPUP00000016593	Cell division cycle 73.	Interacts with SUPT6H, CTD assembly factor 1.	0.659
CDC73	LEO1	ENSMPUP00000004608	ENSMPUP00000007593	Cell division cycle 73.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.999
CDC73	PAF1	ENSMPUP00000004608	ENSMPUP00000017617	Cell division cycle 73.	PAF1 homolog, Paf1/RNA polymerase II complex component.	0.998
CDC73	RTF1	ENSMPUP00000004608	ENSMPUP00000008835	Cell division cycle 73.	RTF1 homolog, Paf1/RNA polymerase II complex component.	0.998
CDC73	SUPT4H1	ENSMPUP00000004608	ENSMPUP00000015216	Cell division cycle 73.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.941
CDC73	UVSSA	ENSMPUP00000004608	ENSMPUP00000011080	Cell division cycle 73.	UV stimulated scaffold protein A.	0.554
CDC73	WAC	ENSMPUP00000004608	ENSMPUP00000014961	Cell division cycle 73.	WW domain containing adaptor with coiled-coil.	0.596
CTR9	AGO2	ENSMPUP00000012777	ENSMPUP00000001914	CTR9 homolog, Paf1/RNA polymerase II complex component.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.417
CTR9	CDC73	ENSMPUP00000012777	ENSMPUP00000004608	CTR9 homolog, Paf1/RNA polymerase II complex component.	Cell division cycle 73.	0.999
CTR9	ELOF1	ENSMPUP00000012777	ENSMPUP00000004868	CTR9 homolog, Paf1/RNA polymerase II complex component.	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family.	0.646
CTR9	ELP2	ENSMPUP00000012777	ENSMPUP00000001116	CTR9 homolog, Paf1/RNA polymerase II complex component.	Elongator acetyltransferase complex subunit 2.	0.433
CTR9	G9K828_MUSPF	ENSMPUP00000012777	ENSMPUP00000007605	CTR9 homolog, Paf1/RNA polymerase II complex component.	Senescence downregulated leo1-like protein.	0.992
CTR9	IWS1	ENSMPUP00000012777	ENSMPUP00000016593	CTR9 homolog, Paf1/RNA polymerase II complex component.	Interacts with SUPT6H, CTD assembly factor 1.	0.896
CTR9	LEO1	ENSMPUP00000012777	ENSMPUP00000007593	CTR9 homolog, Paf1/RNA polymerase II complex component.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.999
CTR9	PAF1	ENSMPUP00000012777	ENSMPUP00000017617	CTR9 homolog, Paf1/RNA polymerase II complex component.	PAF1 homolog, Paf1/RNA polymerase II complex component.	0.998