STRINGSTRING
ACVRL1 ACVRL1 THBS1 THBS1 M3XPB7_MUSPF M3XPB7_MUSPF DLL4 DLL4 MMRN2 MMRN2 AIMP1 AIMP1 GDF2 GDF2 VASH1 VASH1 ATOH8 ATOH8 ALOX5 ALOX5 SULF1 SULF1 TNF TNF STAT1 STAT1 M3YMM9_MUSPF M3YMM9_MUSPF MEF2C MEF2C NF1 NF1 APOH APOH NGFR NGFR PDCD10 PDCD10 M3YAR0_MUSPF M3YAR0_MUSPF TBC1D31 TBC1D31 CNMD CNMD TNMD TNMD FLT1 FLT1 TGFBR1 TGFBR1 CAV1 CAV1 CAV2 CAV2 SYNJ2BP SYNJ2BP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
THBS1Thrombospondin 1. (1170 aa)
M3XPB7_MUSPFATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (554 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
MMRN2Multimerin 2. (925 aa)
AIMP1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (320 aa)
GDF2Growth differentiation factor 2. (429 aa)
VASH1Vasohibin 1. (363 aa)
ATOH8Atonal bHLH transcription factor 8. (323 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (867 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
M3YMM9_MUSPFUncharacterized protein; Belongs to the ATPase alpha/beta chains family. (522 aa)
MEF2CMyocyte enhancer factor 2C. (433 aa)
NF1Neurofibromin 1. (2815 aa)
APOHApolipoprotein H. (345 aa)
NGFRNerve growth factor receptor. (429 aa)
PDCD10Programmed cell death 10. (212 aa)
M3YAR0_MUSPFUncharacterized protein. (736 aa)
TBC1D31TBC1 domain family member 31. (1125 aa)
CNMDChondromodulin. (360 aa)
TNMDTenomodulin. (317 aa)
FLT1Receptor protein-tyrosine kinase. (1338 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (480 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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