STRINGSTRING
F2RL1 F2RL1 FEM1B FEM1B M3XMV4_MUSPF M3XMV4_MUSPF NKX3-2 NKX3-2 BMP6 BMP6 M3XP30_MUSPF M3XP30_MUSPF VSIG1 VSIG1 GDF11 GDF11 MSN MSN M3XQH2_MUSPF M3XQH2_MUSPF BFSP1 BFSP1 TP63 TP63 STC1 STC1 SPDEF SPDEF BCL11B BCL11B BMP5 BMP5 MYD88 MYD88 FRZB FRZB POF1B POF1B COL22A1 COL22A1 BHLHA15 BHLHA15 CLDN3 CLDN3 SFN SFN MYADM MYADM CCM2 CCM2 RAPGEF2 RAPGEF2 FOSL2 FOSL2 TBC1D20 TBC1D20 ASXL1 ASXL1 SIPA1L3 SIPA1L3 SPINT2 SPINT2 SRC SRC HNF4A HNF4A TGFB1 TGFB1 FRS2 FRS2 ONECUT2 ONECUT2 UBIAD1 UBIAD1 EPHA2 EPHA2 FOXA1 FOXA1 IFT74 IFT74 SOX8 SOX8 PLOD3 PLOD3 CLIC4 CLIC4 KDF1 KDF1 IQGAP1 IQGAP1 IL16 IL16 HOXB13 HOXB13 PDPK1 PDPK1 PECAM1 PECAM1 HPSE HPSE MARVELD2 MARVELD2 SOX9 SOX9 ROS1 ROS1 BMP15 BMP15 F11R F11R LAMB2 LAMB2 FOXJ1 FOXJ1 PROX1 PROX1 M3YPM9_MUSPF M3YPM9_MUSPF PDGFB PDGFB FCRL5 FCRL5 RARB RARB EPAS1 EPAS1 VIM VIM M3YJA7_MUSPF M3YJA7_MUSPF NOTCH1 NOTCH1 PAX6 PAX6 FASN FASN TJP1 TJP1 FSHR FSHR SLC9A4 SLC9A4 ESR1 ESR1 COL18A1 COL18A1 FAT1 FAT1 KLF5 KLF5 M3YEN4_MUSPF M3YEN4_MUSPF PDE2A PDE2A BFSP2 BFSP2 M3YE80_MUSPF M3YE80_MUSPF M3YDW6_MUSPF M3YDW6_MUSPF PRDM1 PRDM1 TIGAR TIGAR TGFB3 TGFB3 ST14 ST14 SHROOM3 SHROOM3 CDK6 CDK6 M3Y931_MUSPF M3Y931_MUSPF CCDC88C CCDC88C SLC4A5 SLC4A5 ABCA12 ABCA12 PALLD PALLD IL6ST IL6ST YAP1 YAP1 MET MET DLL1 DLL1 EDNRA EDNRA COL15A1 COL15A1 JAG1 JAG1 HIF1A HIF1A TMOD1 TMOD1 ROBO4 ROBO4 ARID4A ARID4A RARG RARG NPHS1 NPHS1 EXPH5 EXPH5 SMO SMO GPAT4 GPAT4 E2F4 E2F4 ROCK1 ROCK1 BMP4 BMP4 PTPRS PTPRS NPHS2 NPHS2 EZR EZR KDR KDR M3Y0V5_MUSPF M3Y0V5_MUSPF ATRX ATRX HOXA13 HOXA13 RAP1A RAP1A RAB25 RAB25 HOXA5 HOXA5 ADAMTSL4 ADAMTSL4 YIPF6 YIPF6 TMEM79 TMEM79 SIDT2 SIDT2 B4GALT1 B4GALT1 HEG1 HEG1 HAPLN2 HAPLN2 MYO1E MYO1E TJP3 TJP3 NOTCH2 NOTCH2 C1GALT1 C1GALT1 RILPL1 RILPL1 RILPL2 RILPL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F2RL1F2R like trypsin receptor 1. (397 aa)
FEM1BFem-1 homolog B. (627 aa)
M3XMV4_MUSPFUncharacterized protein. (466 aa)
NKX3-2NK3 homeobox 2. (331 aa)
BMP6Bone morphogenetic protein 6. (426 aa)
M3XP30_MUSPFUncharacterized protein. (695 aa)
VSIG1V-set and immunoglobulin domain containing 1. (408 aa)
GDF11Growth differentiation factor 11. (404 aa)
MSNMoesin. (577 aa)
M3XQH2_MUSPFUncharacterized protein. (130 aa)
BFSP1Beaded filament structural protein 1; Belongs to the intermediate filament family. (638 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (586 aa)
STC1Stanniocalcin 1. (247 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (335 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (585 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
FRZBFrizzled related protein. (325 aa)
POF1BPOF1B actin binding protein. (580 aa)
COL22A1Collagen type XXII alpha 1 chain. (1609 aa)
BHLHA15Basic helix-loop-helix family member a15. (187 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
SFN14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
CCM2CCM2 scaffold protein. (426 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1677 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (287 aa)
TBC1D20TBC1 domain family member 20. (351 aa)
ASXL1ASXL transcriptional regulator 1. (1517 aa)
SIPA1L3Signal induced proliferation associated 1 like 3. (1777 aa)
SPINT2Serine peptidase inhibitor, Kunitz type, 2. (252 aa)
SRCTyrosine-protein kinase. (536 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (443 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
FRS2Fibroblast growth factor receptor substrate 2. (517 aa)
ONECUT2One cut domain family member. (395 aa)
UBIAD1UbiA prenyltransferase domain containing 1. (337 aa)
EPHA2EPH receptor A2. (975 aa)
FOXA1Forkhead box A1. (501 aa)
IFT74Intraflagellar transport 74. (600 aa)
SOX8SRY-box transcription factor 8. (377 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (690 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
KDF1Keratinocyte differentiation factor 1. (397 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1627 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1376 aa)
HOXB13Homeobox B13. (290 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (739 aa)
HPSEHeparanase. (540 aa)
MARVELD2MARVEL domain containing 2. (561 aa)
SOX9SRY-box transcription factor 9. (522 aa)
ROS1Tyrosine-protein kinase receptor. (2342 aa)
BMP15Bone morphogenetic protein 15. (404 aa)
F11RF11 receptor. (270 aa)
LAMB2Laminin subunit beta 2. (1801 aa)
FOXJ1Forkhead box J1. (421 aa)
PROX1Prospero homeobox 1. (737 aa)
M3YPM9_MUSPFBZIP domain-containing protein. (351 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (242 aa)
FCRL5Fc receptor like 5. (892 aa)
RARBRetinoic acid receptor beta. (448 aa)
EPAS1Endothelial PAS domain protein 1. (868 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
M3YJA7_MUSPF14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (228 aa)
NOTCH1Notch receptor 1. (2119 aa)
PAX6Paired box 6. (436 aa)
FASNFatty acid synthase. (2309 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1770 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (692 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (701 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (597 aa)
COL18A1Collagen type XVIII alpha 1 chain. (1295 aa)
FAT1FAT atypical cadherin 1. (4588 aa)
KLF5Kruppel like factor 5. (457 aa)
M3YEN4_MUSPFBZIP domain-containing protein. (358 aa)
PDE2APhosphodiesterase. (920 aa)
BFSP2Beaded filament structural protein 2; Belongs to the intermediate filament family. (415 aa)
M3YE80_MUSPFSHSP domain-containing protein; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (214 aa)
M3YDW6_MUSPFUncharacterized protein; Belongs to the MAGUK family. (1112 aa)
PRDM1PR/SET domain 1. (818 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
ST14Suppression of tumorigenicity 14. (859 aa)
SHROOM3Shroom family member 3. (1723 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
M3Y931_MUSPFUncharacterized protein. (203 aa)
CCDC88CCoiled-coil domain containing 88C. (2030 aa)
SLC4A5Anion exchange protein. (1157 aa)
ABCA12ATP binding cassette subfamily A member 12. (2598 aa)
PALLDPalladin, cytoskeletal associated protein. (1124 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
YAP1Yes associated protein 1. (325 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1540 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (602 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
COL15A1Collagen type XV alpha 1 chain. (1381 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
TMOD1Tropomodulin 1. (359 aa)
ROBO4Roundabout guidance receptor 4. (1082 aa)
ARID4AAT-rich interaction domain 4A. (1257 aa)
RARGRetinoic acid receptor gamma. (458 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1242 aa)
EXPH5Exophilin 5. (1998 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (790 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4. (456 aa)
E2F4E2F transcription factor 4. (403 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1252 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1905 aa)
NPHS2NPHS2 stomatin family member, podocin. (398 aa)
EZREzrin. (586 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
M3Y0V5_MUSPFPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (514 aa)
ATRXATRX chromatin remodeler. (2784 aa)
HOXA13Homeobox A13. (259 aa)
RAP1ARAP1A, member of RAS oncogene family. (188 aa)
RAB25RAB25, member RAS oncogene family. (213 aa)
HOXA5Homeobox A5. (270 aa)
ADAMTSL4ADAMTS like 4. (1102 aa)
YIPF6Protein YIPF. (236 aa)
TMEM79Transmembrane protein 79. (395 aa)
SIDT2SID1 transmembrane family member 2. (832 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (387 aa)
HEG1Heart development protein with EGF like domains 1. (1278 aa)
HAPLN2Hyaluronan and proteoglycan link protein 2. (340 aa)
MYO1EMyosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1103 aa)
TJP3Tight junction protein 3. (708 aa)
NOTCH2Notch receptor 2. (2471 aa)
C1GALT1Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (367 aa)
RILPL1Rab interacting lysosomal protein like 1. (386 aa)
RILPL2Rab interacting lysosomal protein like 2. (208 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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