(22 nodes) Regulation of humoral immune response mediated by circulating immunoglobulin network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	M3YEH1_MUSPF	Uncharacterized protein. (316 aa)
	M3YEI9_MUSPF	Uncharacterized protein. (558 aa)
	M3YEH5_MUSPF	Uncharacterized protein. (1473 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	TREML1	Triggering receptor expressed on myeloid cells like 1. (314 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (230 aa)
	FOXJ1	Forkhead box J1. (421 aa)
	LTA	Lymphotoxin alpha; Belongs to the tumor necrosis factor family. (204 aa)
	TNF	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
	M3YGQ3_MUSPF	Uncharacterized protein. (263 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1298 aa)
	C4BPB	Complement component 4 binding protein beta. (256 aa)
	C4BPA	Uncharacterized protein. (605 aa)
	LOC101691328	Uncharacterized protein. (212 aa)
	CSMD3	CUB and Sushi multiple domains 3. (3712 aa)
	M3XUZ6_MUSPF	Uncharacterized protein. (294 aa)
	M3XVB5_MUSPF	Sushi domain-containing protein. (87 aa)
	M3XVC5_MUSPF	Sushi domain-containing protein. (247 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (1013 aa)
	HPX	Hemopexin. (463 aa)
	FCER2	Fc fragment of IgE receptor II. (325 aa)
	M3YEG3_MUSPF	Uncharacterized protein. (619 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C4BPA	C4BPB	ENSMPUP00000009776	ENSMPUP00000009780	Uncharacterized protein.	Complement component 4 binding protein beta.	0.976
C4BPB	C4BPA	ENSMPUP00000009780	ENSMPUP00000009776	Complement component 4 binding protein beta.	Uncharacterized protein.	0.976
C4BPB	LOC101691328	ENSMPUP00000009780	ENSMPUP00000009771	Complement component 4 binding protein beta.	Uncharacterized protein.	0.932
C4BPB	M3YEG3_MUSPF	ENSMPUP00000009780	ENSMPUP00000009720	Complement component 4 binding protein beta.	Uncharacterized protein.	0.460
C4BPB	M3YEH1_MUSPF	ENSMPUP00000009780	ENSMPUP00000009728	Complement component 4 binding protein beta.	Uncharacterized protein.	0.497
C4BPB	M3YEH5_MUSPF	ENSMPUP00000009780	ENSMPUP00000009732	Complement component 4 binding protein beta.	Uncharacterized protein.	0.460
C4BPB	M3YEI9_MUSPF	ENSMPUP00000009780	ENSMPUP00000009746	Complement component 4 binding protein beta.	Uncharacterized protein.	0.562
FCER2	M3YEG3_MUSPF	ENSMPUP00000008080	ENSMPUP00000009720	Fc fragment of IgE receptor II.	Uncharacterized protein.	0.597
FCER2	M3YEH1_MUSPF	ENSMPUP00000008080	ENSMPUP00000009728	Fc fragment of IgE receptor II.	Uncharacterized protein.	0.597
FCER2	M3YEH5_MUSPF	ENSMPUP00000008080	ENSMPUP00000009732	Fc fragment of IgE receptor II.	Uncharacterized protein.	0.597
LOC101691328	C4BPB	ENSMPUP00000009771	ENSMPUP00000009780	Uncharacterized protein.	Complement component 4 binding protein beta.	0.932
LOC101691328	M3XUZ6_MUSPF	ENSMPUP00000009771	ENSMPUP00000002896	Uncharacterized protein.	Uncharacterized protein.	0.875
LTA	TNF	ENSMPUP00000011303	ENSMPUP00000011297	Lymphotoxin alpha; Belongs to the tumor necrosis factor family.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.961
M3XUZ6_MUSPF	LOC101691328	ENSMPUP00000002896	ENSMPUP00000009771	Uncharacterized protein.	Uncharacterized protein.	0.875
M3XUZ6_MUSPF	M3YEI9_MUSPF	ENSMPUP00000002896	ENSMPUP00000009746	Uncharacterized protein.	Uncharacterized protein.	0.461
M3XVB5_MUSPF	M3XVC5_MUSPF	ENSMPUP00000003015	ENSMPUP00000003025	Sushi domain-containing protein.	Sushi domain-containing protein.	0.900
M3XVC5_MUSPF	M3XVB5_MUSPF	ENSMPUP00000003025	ENSMPUP00000003015	Sushi domain-containing protein.	Sushi domain-containing protein.	0.900
M3XVC5_MUSPF	M3YGQ3_MUSPF	ENSMPUP00000003025	ENSMPUP00000010510	Sushi domain-containing protein.	Uncharacterized protein.	0.929
M3YEG3_MUSPF	C4BPB	ENSMPUP00000009720	ENSMPUP00000009780	Uncharacterized protein.	Complement component 4 binding protein beta.	0.460
M3YEG3_MUSPF	FCER2	ENSMPUP00000009720	ENSMPUP00000008080	Uncharacterized protein.	Fc fragment of IgE receptor II.	0.597