47 items (Mustela putorius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMAD6	Mothers against decapentaplegic homolog. (494 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
	NRP2	Neuropilin; Belongs to the neuropilin family. (926 aa)
	EDN1	Endothelin 1. (202 aa)
	LRP2	LDL receptor related protein 2. (4699 aa)
	NPY1R	Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	HAND2	Heart and neural crest derivatives expressed 2. (208 aa)
	TBX3	T-box transcription factor 3. (757 aa)
	CRKL	CRK like proto-oncogene, adaptor protein. (303 aa)
	HES1	Hes family bHLH transcription factor 1. (283 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	SFRP2	Secreted frizzled related protein 2. (294 aa)
	ILK	Integrin linked kinase. (452 aa)
	GATA6	GATA binding protein 6. (482 aa)
	ZFPM2	Zinc finger protein, FOG family member 2. (1151 aa)
	FOXH1	Forkhead box H1. (398 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (824 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	TBX20	T-box transcription factor 20. (446 aa)
	MEF2C	Myocyte enhancer factor 2C. (433 aa)
	M3YA03_MUSPF	Uncharacterized protein. (666 aa)
	SEC24B	SEC24 homolog B, COPII coat complex component. (1285 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
	DVL2	Dishevelled segment polarity protein 2. (734 aa)
	SOX17	SRY-box transcription factor 17. (406 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
	NOTCH1	Notch receptor 1. (2119 aa)
	NKX2-5	NK2 homeobox 5. (323 aa)
	PARVA	Parvin alpha. (372 aa)
	ENG	Endoglin. (653 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
	NIPBL	Nipped-B protein. (2803 aa)
	TBX2	T-box transcription factor 2. (679 aa)
	ELN	Elastin. (782 aa)
	DHRS3	Dehydrogenase/reductase member 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
	PLXND1	Plexin D1. (1746 aa)
	SEMA3C	Semaphorin 3C; Belongs to the semaphorin family. (750 aa)
	GJA5	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
	NPY5R	Neuropeptide Y receptor Y5. (446 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
	NPY2R	Neuropeptide Y receptor Y2; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	FZD2	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (550 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF2	JUN	ENSMPUP00000013878	ENSMPUP00000020047	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.994
BMP4	BMPR1A	ENSMPUP00000005423	ENSMPUP00000008777	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.997
BMP4	BMPR2	ENSMPUP00000005423	ENSMPUP00000000351	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.989
BMP4	FGF8	ENSMPUP00000005423	ENSMPUP00000016793	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.598
BMP4	GATA6	ENSMPUP00000005423	ENSMPUP00000005576	Bone morphogenetic protein 4.	GATA binding protein 6.	0.600
BMP4	HAND2	ENSMPUP00000005423	ENSMPUP00000001892	Bone morphogenetic protein 4.	Heart and neural crest derivatives expressed 2.	0.498
BMP4	JAG1	ENSMPUP00000005423	ENSMPUP00000006461	Bone morphogenetic protein 4.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.666
BMP4	NKX2-5	ENSMPUP00000005423	ENSMPUP00000012613	Bone morphogenetic protein 4.	NK2 homeobox 5.	0.436
BMP4	SMAD4	ENSMPUP00000005423	ENSMPUP00000008705	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.892
BMP4	SMAD6	ENSMPUP00000005423	ENSMPUP00000000305	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.721
BMP4	SOX17	ENSMPUP00000005423	ENSMPUP00000010429	Bone morphogenetic protein 4.	SRY-box transcription factor 17.	0.800
BMP4	TBX3	ENSMPUP00000005423	ENSMPUP00000002691	Bone morphogenetic protein 4.	T-box transcription factor 3.	0.482
BMP4	WNT11	ENSMPUP00000005423	ENSMPUP00000008719	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.418
BMPR1A	BMP4	ENSMPUP00000008777	ENSMPUP00000005423	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.997
BMPR1A	BMPR2	ENSMPUP00000008777	ENSMPUP00000000351	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.969
BMPR1A	SMAD4	ENSMPUP00000008777	ENSMPUP00000008705	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.842
BMPR1A	SMAD6	ENSMPUP00000008777	ENSMPUP00000000305	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.826
BMPR2	BMP4	ENSMPUP00000000351	ENSMPUP00000005423	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.989
BMPR2	BMPR1A	ENSMPUP00000000351	ENSMPUP00000008777	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.969
BMPR2	ENG	ENSMPUP00000000351	ENSMPUP00000013475	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Endoglin.	0.494