19 items (Mustela putorius) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	NSMCE2	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (275 aa)
	RAD21	RAD21 cohesin complex component. (631 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
	SMC5	SMC_N domain-containing protein. (1026 aa)
	MACROH2A1	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
	FAM178B	Family with sequence similarity 178 member B. (654 aa)
	TNKS	Poly [ADP-ribose] polymerase. (1327 aa)
	ATRX	ATRX chromatin remodeler. (2784 aa)
	M3Z7E4_MUSPF	Uncharacterized protein. (1085 aa)
	M3YD28_MUSPF	Uncharacterized protein. (1086 aa)
	SLF2	SMC5-SMC6 complex localization factor 2. (1173 aa)
	M3YU10_MUSPF	RRM domain-containing protein. (311 aa)
	AXIN2	Axin 2. (842 aa)
	M3YLP8_MUSPF	Uncharacterized protein. (433 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	M3Y1V5_MUSPF	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (415 aa)
	WAPL	WAPL cohesin release factor. (1196 aa)
	SLF1	SMC5-SMC6 complex localization factor 1. (1145 aa)
	RB1	RB transcriptional corepressor 1. (948 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATRX	MACROH2A1	ENSMPUP00000000083	ENSMPUP00000009936	ATRX chromatin remodeler.	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.	0.444
ATRX	SMC5	ENSMPUP00000000083	ENSMPUP00000009439	ATRX chromatin remodeler.	SMC_N domain-containing protein.	0.725
AXIN2	CTNNB1	ENSMPUP00000014547	ENSMPUP00000011461	Axin 2.	Catenin beta 1.	0.994
AXIN2	TNKS	ENSMPUP00000014547	ENSMPUP00000011291	Axin 2.	Poly [ADP-ribose] polymerase.	0.950
CTNNB1	AXIN2	ENSMPUP00000011461	ENSMPUP00000014547	Catenin beta 1.	Axin 2.	0.994
CTNNB1	M3Y1V5_MUSPF	ENSMPUP00000011461	ENSMPUP00000005306	Catenin beta 1.	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.580
CTNNB1	TNKS	ENSMPUP00000011461	ENSMPUP00000011291	Catenin beta 1.	Poly [ADP-ribose] polymerase.	0.659
FEN1	SLF1	ENSMPUP00000019865	ENSMPUP00000004179	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	SMC5-SMC6 complex localization factor 1.	0.514
M3Y1V5_MUSPF	CTNNB1	ENSMPUP00000005306	ENSMPUP00000011461	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Catenin beta 1.	0.580
M3Y1V5_MUSPF	MACROH2A1	ENSMPUP00000005306	ENSMPUP00000009936	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.	0.890
M3Y1V5_MUSPF	RB1	ENSMPUP00000005306	ENSMPUP00000001411	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	RB transcriptional corepressor 1.	0.741
M3Y1V5_MUSPF	WAPL	ENSMPUP00000005306	ENSMPUP00000008612	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	WAPL cohesin release factor.	0.635
M3YD28_MUSPF	M3YLP8_MUSPF	ENSMPUP00000009235	ENSMPUP00000012255	Uncharacterized protein.	Uncharacterized protein.	0.519
M3YLP8_MUSPF	M3YD28_MUSPF	ENSMPUP00000012255	ENSMPUP00000009235	Uncharacterized protein.	Uncharacterized protein.	0.519
M3YLP8_MUSPF	M3Z7E4_MUSPF	ENSMPUP00000012255	ENSMPUP00000019507	Uncharacterized protein.	Uncharacterized protein.	0.519
M3YLP8_MUSPF	RAD21	ENSMPUP00000012255	ENSMPUP00000000981	Uncharacterized protein.	RAD21 cohesin complex component.	0.834
M3YLP8_MUSPF	SMC5	ENSMPUP00000012255	ENSMPUP00000009439	Uncharacterized protein.	SMC_N domain-containing protein.	0.490
M3YLP8_MUSPF	WAPL	ENSMPUP00000012255	ENSMPUP00000008612	Uncharacterized protein.	WAPL cohesin release factor.	0.984
M3Z7E4_MUSPF	M3YLP8_MUSPF	ENSMPUP00000019507	ENSMPUP00000012255	Uncharacterized protein.	Uncharacterized protein.	0.519
MACROH2A1	ATRX	ENSMPUP00000009936	ENSMPUP00000000083	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.	ATRX chromatin remodeler.	0.444