STRINGSTRING
RIPOR1 RIPOR1 ZNF304 ZNF304 RHOJ RHOJ PLEKHG5 PLEKHG5 RAB15 RAB15 DNMT1 DNMT1 CTNNAL1 CTNNAL1 SYNJ2BP SYNJ2BP KIAA0355 KIAA0355 KITLG KITLG ELMO1 ELMO1 USP50 USP50 USP8 USP8 RTKN RTKN RANGRF RANGRF EPS8L1 EPS8L1 RAB30 RAB30 M3YA49_MUSPF M3YA49_MUSPF TRIM28 TRIM28 M3YA60_MUSPF M3YA60_MUSPF DOK1 DOK1 RASGRF2 RASGRF2 RHOV RHOV TP53 TP53 MRAS MRAS CDH13 CDH13 GDI1 GDI1 WASF1 WASF1 RASGRP3 RASGRP3 KRAS KRAS SOS1 SOS1 NKIRAS2 NKIRAS2 M3YH21_MUSPF M3YH21_MUSPF M3YH29_MUSPF M3YH29_MUSPF PPP1R21 PPP1R21 RAC3 RAC3 AIF1 AIF1 EPS8 EPS8 RERG RERG ARHGDIB ARHGDIB RAP2A RAP2A RGL1 RGL1 M3YKJ9_MUSPF M3YKJ9_MUSPF DOK3 DOK3 RHOU RHOU TAX1BP3 TAX1BP3 NKIRAS1 NKIRAS1 BRAP BRAP CDKN1A CDKN1A KSR1 KSR1 NF1 NF1 RAB9A RAB9A RAP2B RAP2B CDC42EP3 CDC42EP3 RALGPS1 RALGPS1 DBNL DBNL RALA RALA RAPGEF2 RAPGEF2 GNA12 GNA12 RASGRP4 RASGRP4 M3Z1V3_MUSPF M3Z1V3_MUSPF RAP1B RAP1B RHOB RHOB RHOG RHOG CDC42EP4 CDC42EP4 CDC42EP2 CDC42EP2 RHOH RHOH RACGAP1 RACGAP1 JUN JUN ARHGAP5 ARHGAP5 RIT2 RIT2 RALB RALB CDK2 CDK2 RAPGEF4 RAPGEF4 RASGEF1C RASGEF1C HACD3 HACD3 M3XMV4_MUSPF M3XMV4_MUSPF FARP2 FARP2 M3XLW8_MUSPF M3XLW8_MUSPF MAPKAPK5 MAPKAPK5 SYNGAP1 SYNGAP1 RAPGEF5 RAPGEF5 WAS WAS RHOA RHOA TMEM19 TMEM19 RAB21 RAB21 CCNA2 CCNA2 CYFIP1 CYFIP1 RASGEF1A RASGEF1A PLCE1 PLCE1 NISCH NISCH RAC1 RAC1 SGSM3 SGSM3 PDPN PDPN M3YXN1_MUSPF M3YXN1_MUSPF RAB39B RAB39B RAB33B RAB33B PDIA2 PDIA2 M3YX33_MUSPF M3YX33_MUSPF MYO9B MYO9B CNKSR1 CNKSR1 WASF2 WASF2 PHACTR4 PHACTR4 RFXANK RFXANK RASGRF1 RASGRF1 ITGA3 ITGA3 NGFR NGFR KPNB1 KPNB1 M3YUE6_MUSPF M3YUE6_MUSPF RRAS RRAS CELSR1 CELSR1 GPSM2 GPSM2 KSR2 KSR2 RAB35 RAB35 SHTN1 SHTN1 BCL6 BCL6 ARHGEF11 ARHGEF11 EPS8L3 EPS8L3 CSF1 CSF1 DGKI DGKI M3XYN0_MUSPF M3XYN0_MUSPF IQGAP3 IQGAP3 DOK2 DOK2 ADGRG1 ADGRG1 RAB12 RAB12 RAP1A RAP1A SOS2 SOS2 M3Y130_MUSPF M3Y130_MUSPF ARHGAP35 ARHGAP35 RHOC RHOC RALGPS2 RALGPS2 RGL3 RGL3 RIT1 RIT1 PRKD1 PRKD1 ROCK1 ROCK1 ARHGEF12 ARHGEF12 M3Y2Z6_MUSPF M3Y2Z6_MUSPF RAB39A RAB39A RAPGEF1 RAPGEF1 RAC2 RAC2 RASGRP2 RASGRP2 RAP2C RAP2C NCKAP1 NCKAP1 COL1A2 COL1A2 RB1 RB1 M3XQ42_MUSPF M3XQ42_MUSPF M3XPU1_MUSPF M3XPU1_MUSPF M3Z630_MUSPF M3Z630_MUSPF RAB9B RAB9B CDC42EP1 CDC42EP1 LAT LAT RASSF1 RASSF1 RAPGEFL1 RAPGEFL1 RASGEF1B RASGEF1B RRAS2 RRAS2 GNA13 GNA13 ROCK2 ROCK2 RALGDS RALGDS RAB4A RAB4A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RIPOR1RHO family interacting cell polarization regulator 1. (1319 aa)
ZNF304Zinc finger protein 304. (668 aa)
RHOJRas homolog family member J. (282 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1036 aa)
RAB15RAB15, member RAS oncogene family. (177 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1674 aa)
CTNNAL1Catenin alpha like 1. (602 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
KIAA0355KIAA0355. (1069 aa)
KITLGKIT ligand. (274 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
USP50Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (376 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1116 aa)
RTKNRhotekin. (564 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
EPS8L1EPS8 like 1. (802 aa)
RAB30RAB30, member RAS oncogene family. (203 aa)
M3YA49_MUSPFUncharacterized protein. (659 aa)
TRIM28Tripartite motif containing 28. (700 aa)
M3YA60_MUSPFN-terminal Ras-GEF domain-containing protein. (178 aa)
DOK1Docking protein 1. (483 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1179 aa)
RHOVRas homolog family member V. (236 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
CDH13Cadherin 13. (662 aa)
GDI1Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (447 aa)
WASF1WASP family member 1. (559 aa)
RASGRP3RAS guanyl releasing protein 3. (692 aa)
KRASKRAS proto-oncogene, GTPase. (208 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1276 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (191 aa)
M3YH21_MUSPFRas-GEF domain-containing protein. (251 aa)
M3YH29_MUSPFUncharacterized protein. (180 aa)
PPP1R21Protein phosphatase 1 regulatory subunit 21. (798 aa)
RAC3Rac family small GTPase 3. (160 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (821 aa)
RERGRAS like estrogen regulated growth inhibitor. (199 aa)
ARHGDIBRho GDP dissociation inhibitor beta. (200 aa)
RAP2ARAP2A, member of RAS oncogene family. (138 aa)
RGL1Ral guanine nucleotide dissociation stimulator like 1. (768 aa)
M3YKJ9_MUSPFUncharacterized protein. (156 aa)
DOK3Docking protein 3. (447 aa)
RHOURas homolog family member U. (173 aa)
TAX1BP3Tax1 binding protein 3. (124 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (192 aa)
BRAPBRCA1 associated protein. (592 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
KSR1Kinase suppressor of ras 1. (848 aa)
NF1Neurofibromin 1. (2815 aa)
RAB9ARAB9A, member RAS oncogene family. (201 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
CDC42EP3CDC42 effector protein 3. (254 aa)
RALGPS1Ral GEF with PH domain and SH3 binding motif 1. (585 aa)
DBNLDrebrin like. (432 aa)
RALARAS like proto-oncogene A. (206 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1677 aa)
GNA12G protein subunit alpha 12. (305 aa)
RASGRP4RAS guanyl releasing protein 4. (490 aa)
M3Z1V3_MUSPFUncharacterized protein. (213 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
RHOBRas homolog family member B. (196 aa)
RHOGRas homolog family member G. (191 aa)
CDC42EP4CDC42 effector protein 4. (354 aa)
CDC42EP2Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (214 aa)
RHOHRas homolog family member H. (191 aa)
RACGAP1Rac GTPase activating protein 1. (631 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
ARHGAP5Rho GTPase activating protein 5. (1503 aa)
RIT2Ras like without CAAX 2. (218 aa)
RALBRAS like proto-oncogene B. (206 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (334 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1011 aa)
RASGEF1CRasGEF domain family member 1C. (495 aa)
HACD3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (362 aa)
M3XMV4_MUSPFUncharacterized protein. (466 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1062 aa)
M3XLW8_MUSPFUncharacterized protein. (183 aa)
MAPKAPK5MAPK activated protein kinase 5. (473 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1205 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (730 aa)
WASWASP actin nucleation promoting factor. (501 aa)
RHOARas homolog family member A. (193 aa)
TMEM19Transmembrane protein 19. (322 aa)
RAB21RAB21, member RAS oncogene family. (224 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
RASGEF1ARasGEF domain family member 1A. (546 aa)
PLCE1Phosphoinositide phospholipase C. (2292 aa)
NISCHNischarin. (1289 aa)
RAC1Rac family small GTPase 1. (167 aa)
SGSM3Small G protein signaling modulator 3. (751 aa)
PDPNPodoplanin. (177 aa)
M3YXN1_MUSPFUncharacterized protein. (506 aa)
RAB39BRAB39B, member RAS oncogene family. (213 aa)
RAB33BRAB33B, member RAS oncogene family. (229 aa)
PDIA2Protein disulfide isomerase family A member 2. (547 aa)
M3YX33_MUSPFUncharacterized protein. (191 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2161 aa)
CNKSR1Connector enhancer of kinase suppressor of Ras 1. (791 aa)
WASF2WASP family member 2. (498 aa)
PHACTR4Phosphatase and actin regulator. (708 aa)
RFXANKRegulatory factor X associated ankyrin containing protein. (260 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1276 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1138 aa)
NGFRNerve growth factor receptor. (429 aa)
KPNB1Karyopherin subunit beta 1. (877 aa)
M3YUE6_MUSPFDeath domain-containing protein. (233 aa)
RRASRAS related. (218 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2735 aa)
GPSM2G protein signaling modulator 2. (681 aa)
KSR2Kinase suppressor of ras 2. (968 aa)
RAB35RAB35, member RAS oncogene family. (201 aa)
SHTN1Shootin 1. (576 aa)
BCL6BCL6 transcription repressor. (706 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1536 aa)
EPS8L3EPS8 like 3. (645 aa)
CSF1Colony stimulating factor 1. (517 aa)
DGKIDiacylglycerol kinase. (999 aa)
M3XYN0_MUSPFUncharacterized protein. (192 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1610 aa)
DOK2Docking protein 2. (407 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (687 aa)
RAB12RAB12, member RAS oncogene family. (186 aa)
RAP1ARAP1A, member of RAS oncogene family. (188 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1281 aa)
M3Y130_MUSPFUncharacterized protein. (200 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
RHOCRas homolog family member C. (193 aa)
RALGPS2Ral GEF with PH domain and SH3 binding motif 2. (583 aa)
RGL3Ral guanine nucleotide dissociation stimulator like 3. (844 aa)
RIT1Ras like without CAAX 1. (181 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (824 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1252 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1544 aa)
M3Y2Z6_MUSPFUncharacterized protein. (189 aa)
RAB39ARAB39A, member RAS oncogene family. (176 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1265 aa)
RAC2Rac family small GTPase 2. (192 aa)
RASGRP2RAS guanyl releasing protein 2. (659 aa)
RAP2CRAP2C, member of RAS oncogene family. (183 aa)
NCKAP1NCK associated protein 1. (1126 aa)
COL1A2Collagen type I alpha 2 chain. (1367 aa)
RB1RB transcriptional corepressor 1. (948 aa)
M3XQ42_MUSPFRas-GEF domain-containing protein. (289 aa)
M3XPU1_MUSPFRas-GEF domain-containing protein. (277 aa)
M3Z630_MUSPFUncharacterized protein. (200 aa)
RAB9BRAB9B, member RAS oncogene family. (201 aa)
CDC42EP1CDC42 effector protein 1. (368 aa)
LATLinker for activation of T cells. (260 aa)
RASSF1Ras association domain family member 1. (272 aa)
RAPGEFL1Rap guanine nucleotide exchange factor like 1. (456 aa)
RASGEF1BRasGEF domain family member 1B. (472 aa)
RRAS2RAS related 2. (181 aa)
GNA13G protein subunit alpha 13. (284 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1389 aa)
RALGDSUncharacterized protein. (888 aa)
RAB4ARAB4A, member RAS oncogene family. (215 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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