STRINGSTRING
MED12 MED12 M3Z8Z7_MUSPF M3Z8Z7_MUSPF AMER3 AMER3 AMER1 AMER1 GLI3 GLI3 M3Z2K4_MUSPF M3Z2K4_MUSPF NUMBL NUMBL TBL1XR1 TBL1XR1 BTRC BTRC SUFU SUFU LZIC LZIC EP300 EP300 AXIN1 AXIN1 SLC9A3R2 SLC9A3R2 PTPRU PTPRU TRPC4 TRPC4 AXIN2 AXIN2 PTPRK PTPRK PIN1 PIN1 DVL1 DVL1 SOX9 SOX9 SLC9A3R1 SLC9A3R1 HDAC6 HDAC6 SOX30 SOX30 CBY1 CBY1 APC APC TAX1BP3 TAX1BP3 M3YKK2_MUSPF M3YKK2_MUSPF M3YKJ5_MUSPF M3YKJ5_MUSPF M3YKB9_MUSPF M3YKB9_MUSPF M3YI89_MUSPF M3YI89_MUSPF CXADR CXADR AR AR SOX17 SOX17 ESR1 ESR1 SPECC1 SPECC1 TCF7 TCF7 ASH2L ASH2L FOXO3 FOXO3 M3YEF8_MUSPF M3YEF8_MUSPF CTNNA1 CTNNA1 KDM6B KDM6B CDHR5 CDHR5 LEF1 LEF1 TCF7L1 TCF7L1 CTNNA2 CTNNA2 M3YAW2_MUSPF M3YAW2_MUSPF GSK3B GSK3B APC2 APC2 KANK3 KANK3 AJAP1 AJAP1 CDH26 CDH26 DACT1 DACT1 CALCOCO1 CALCOCO1 KANK2 KANK2 KANK1 KANK1 CDH5 CDH5 BCL9L BCL9L CHD8 CHD8 BCL9 BCL9 AMER2 AMER2 RORA RORA SMAD7 SMAD7 M3XPQ5_MUSPF M3XPQ5_MUSPF TCF7L2 TCF7L2 M3XSG3_MUSPF M3XSG3_MUSPF DVL3 DVL3 MED12L MED12L SPECC1L SPECC1L SALL1 SALL1 RUVBL2 RUVBL2 VCL VCL PTPRJ PTPRJ PSEN1 PSEN1 NUMB NUMB DLG5 DLG5 M3XZQ7_MUSPF M3XZQ7_MUSPF M3XZR5_MUSPF M3XZR5_MUSPF FOXO4 FOXO4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MED12Mediator complex subunit 12. (2168 aa)
M3Z8Z7_MUSPFUncharacterized protein. (500 aa)
AMER3APC membrane recruitment protein 3. (812 aa)
AMER1APC membrane recruitment protein 1. (1134 aa)
GLI3GLI family zinc finger 3. (1585 aa)
M3Z2K4_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
NUMBLNUMB like endocytic adaptor protein. (593 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (514 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (567 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (484 aa)
LZICLeucine zipper and CTNNBIP1 domain containing. (190 aa)
EP300E1A binding protein p300. (2425 aa)
AXIN1Axin 1. (862 aa)
SLC9A3R2Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (337 aa)
PTPRUProtein tyrosine phosphatase receptor type U. (1436 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
AXIN2Axin 2. (842 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1463 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (162 aa)
DVL1Dishevelled segment polarity protein 1. (691 aa)
SOX9SRY-box transcription factor 9. (522 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
HDAC6Histone deacetylase 6. (1199 aa)
SOX30SRY-box transcription factor 30. (768 aa)
CBY1Chibby family member 1, beta catenin antagonist. (127 aa)
APCAPC regulator of WNT signaling pathway. (2862 aa)
TAX1BP3Tax1 binding protein 3. (124 aa)
M3YKK2_MUSPFUncharacterized protein. (220 aa)
M3YKJ5_MUSPFUncharacterized protein. (247 aa)
M3YKB9_MUSPFUncharacterized protein. (1910 aa)
M3YI89_MUSPFUncharacterized protein. (271 aa)
CXADRUncharacterized protein. (386 aa)
ARAndrogen receptor. (892 aa)
SOX17SRY-box transcription factor 17. (406 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (597 aa)
SPECC1Sperm antigen with calponin homology and coiled-coil domains 1. (1059 aa)
TCF7Transcription factor 7. (339 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (628 aa)
FOXO3Forkhead box O3. (671 aa)
M3YEF8_MUSPFFOXO-TAD domain-containing protein. (399 aa)
CTNNA1Catenin alpha 1. (930 aa)
KDM6BLysine demethylase 6B. (1668 aa)
CDHR5Cadherin related family member 5. (841 aa)
LEF1Lymphoid enhancer binding factor 1. (400 aa)
TCF7L1Transcription factor 7 like 1. (490 aa)
CTNNA2Catenin alpha 2. (521 aa)
M3YAW2_MUSPFUncharacterized protein. (429 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
APC2APC regulator of WNT signaling pathway 2. (2481 aa)
KANK3KN motif and ankyrin repeat domains 3. (827 aa)
AJAP1Adherens junctions associated protein 1. (414 aa)
CDH26Cadherin 26. (733 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (759 aa)
CALCOCO1Calcium binding and coiled-coil domain 1. (692 aa)
KANK2KN motif and ankyrin repeat domains 2. (851 aa)
KANK1KN motif and ankyrin repeat domains 1. (1352 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa)
BCL9LBCL9 like. (1276 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2580 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
AMER2APC membrane recruitment protein 2. (640 aa)
RORARAR related orphan receptor A. (430 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
M3XPQ5_MUSPFWD_REPEATS_REGION domain-containing protein. (366 aa)
TCF7L2Transcription factor 7 like 2. (514 aa)
M3XSG3_MUSPFCTNNB1_binding domain-containing protein. (169 aa)
DVL3Dishevelled segment polarity protein 3. (718 aa)
MED12LMediator complex subunit 12L. (2190 aa)
SPECC1LCalponin-homology (CH) domain-containing protein. (1118 aa)
SALL1Spalt like transcription factor 1. (1337 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
VCLVinculin. (1134 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1219 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (464 aa)
NUMBNUMB endocytic adaptor protein. (653 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1922 aa)
M3XZQ7_MUSPFUbiquitin-like domain-containing protein. (311 aa)
M3XZR5_MUSPFRBR-type E3 ubiquitin transferase. (115 aa)
FOXO4Forkhead box O4. (509 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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