(53 nodes) Associative learning network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RIC8A	RIC8 guanine nucleotide exchange factor A. (501 aa)
	M3XMV4_MUSPF	Uncharacterized protein. (466 aa)
	TANC1	Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1. (1874 aa)
	TBR1	T-box brain transcription factor 1. (682 aa)
	GABRA5	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
	SHANK1	SH3 and multiple ankyrin repeat domains 1. (1954 aa)
	SHANK3	SH3 and multiple ankyrin repeat domains 3. (1712 aa)
	SYNGAP1	Synaptic Ras GTPase activating protein 1. (1205 aa)
	NPS	Neuropeptide S. (68 aa)
	M3XTZ9_MUSPF	Uncharacterized protein. (207 aa)
	CSMD1	CUB and Sushi multiple domains 1. (2957 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (715 aa)
	DRD2	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (443 aa)
	TTC36	Tetratricopeptide repeat domain 36. (188 aa)
	NDRG4	NDRG family member 4. (391 aa)
	TNR	Tenascin R. (1358 aa)
	PDE1B	Phosphodiesterase. (535 aa)
	HMGCR	3-hydroxy-3-methylglutaryl coenzyme A reductase. (914 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (798 aa)
	LRRN4	Leucine rich repeat neuronal 4. (745 aa)
	SNAP25	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (824 aa)
	LGMN	Legumain. (433 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	ABCA7	ATP binding cassette subfamily A member 7. (2152 aa)
	MECP2	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (484 aa)
	UCN	Urocortin. (126 aa)
	DDHD2	DDHD domain containing 2. (713 aa)
	KRAS	KRAS proto-oncogene, GTPase. (208 aa)
	ZZEF1	Zinc finger ZZ-type and EF-hand domain containing 1. (2829 aa)
	BTG2	BTG anti-proliferation factor 2. (162 aa)
	CTNS	Cystinosin, lysosomal cystine transporter. (388 aa)
	TSC1	TSC complex subunit 1. (1165 aa)
	ABL1	Tyrosine-protein kinase. (1150 aa)
	SRF	Serum response factor. (508 aa)
	B4GALT2	Beta-1,4-galactosyltransferase 2. (369 aa)
	PTRHD1	Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
	IFT20	Intraflagellar transport 20. (157 aa)
	NF1	Neurofibromin 1. (2815 aa)
	GRIN2A	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1307 aa)
	CSMD2	CUB and Sushi multiple domains 2. (3298 aa)
	PPP1R1B	Protein phosphatase 1 regulatory inhibitor subunit 1B. (206 aa)
	SLC7A11	Solute carrier family 7 member 11. (503 aa)
	NPTX2	Neuronal pentraxin 2. (386 aa)
	NETO1	Neuropilin and tolloid like 1. (533 aa)
	TAFA2	TAFA chemokine like family member 2. (131 aa)
	SLC6A1	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
	NPTN	Neuroplastin. (398 aa)
	RELN	Reelin. (3458 aa)
	NRGN	Neurogranin. (78 aa)
	FOXB1	Forkhead box B1. (325 aa)
	DRD5	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (474 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	CDK5	ENSMPUP00000012584	ENSMPUP00000008272	Tyrosine-protein kinase.	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	0.471
ADCY3	M3XMV4_MUSPF	ENSMPUP00000013920	ENSMPUP00000000404	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.842
ADCY3	PDE1B	ENSMPUP00000013920	ENSMPUP00000005578	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.839
BRAF	HIF1A	ENSMPUP00000003381	ENSMPUP00000006460	B-Raf proto-oncogene, serine/threonine kinase.	Hypoxia inducible factor 1 subunit alpha.	0.467
BRAF	KRAS	ENSMPUP00000003381	ENSMPUP00000010217	B-Raf proto-oncogene, serine/threonine kinase.	KRAS proto-oncogene, GTPase.	0.981
BRAF	NF1	ENSMPUP00000003381	ENSMPUP00000014319	B-Raf proto-oncogene, serine/threonine kinase.	Neurofibromin 1.	0.747
BRAF	TSC1	ENSMPUP00000003381	ENSMPUP00000012397	B-Raf proto-oncogene, serine/threonine kinase.	TSC complex subunit 1.	0.467
CDK5	ABL1	ENSMPUP00000008272	ENSMPUP00000012584	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.471
CDK5	PPP1R1B	ENSMPUP00000008272	ENSMPUP00000014887	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Protein phosphatase 1 regulatory inhibitor subunit 1B.	0.944
DRD2	DRD5	ENSMPUP00000003847	ENSMPUP00000019672	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	0.866
DRD2	PPP1R1B	ENSMPUP00000003847	ENSMPUP00000014887	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	Protein phosphatase 1 regulatory inhibitor subunit 1B.	0.540
DRD5	DRD2	ENSMPUP00000019672	ENSMPUP00000003847	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	0.866
DRD5	GABRA5	ENSMPUP00000019672	ENSMPUP00000000640	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.534
GABRA5	DRD5	ENSMPUP00000000640	ENSMPUP00000019672	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	0.534
GABRA5	SLC6A1	ENSMPUP00000000640	ENSMPUP00000017061	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.465
GRIN2A	MECP2	ENSMPUP00000014591	ENSMPUP00000008999	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	0.465
GRIN2A	SHANK1	ENSMPUP00000014591	ENSMPUP00000001600	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	SH3 and multiple ankyrin repeat domains 1.	0.495
GRIN2A	SHANK3	ENSMPUP00000014591	ENSMPUP00000001849	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	SH3 and multiple ankyrin repeat domains 3.	0.489
HIF1A	BRAF	ENSMPUP00000006460	ENSMPUP00000003381	Hypoxia inducible factor 1 subunit alpha.	B-Raf proto-oncogene, serine/threonine kinase.	0.467
HIF1A	KRAS	ENSMPUP00000006460	ENSMPUP00000010217	Hypoxia inducible factor 1 subunit alpha.	KRAS proto-oncogene, GTPase.	0.511