54 items (Mustela putorius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HSBP1	Uncharacterized protein. (115 aa)
	TP53INP1	Tumor protein p53 inducible nuclear protein 1. (239 aa)
	ASIC3	Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (533 aa)
	HTRA2	HtrA serine peptidase 2. (533 aa)
	FGF1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	TFEC	Transcription factor EC. (347 aa)
	HSF1	Heat shock transcription factor 1. (555 aa)
	HSPB6	Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family. (182 aa)
	CKM	Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family. (380 aa)
	ANO1	Anoctamin. (888 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	PSIP1	PC4 and SFRS1 interacting protein 1. (531 aa)
	TRPV4	Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (873 aa)
	M3XWY3_MUSPF	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (163 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
	BAG3	BCL2 associated athanogene 3. (597 aa)
	ARPP21	cAMP regulated phosphoprotein 21. (845 aa)
	RBBP7	RB binding protein 7, chromatin remodeling factor. (469 aa)
	P2RX3	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
	SCARA5	Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] (489 aa)
	M3XSM2_MUSPF	Uncharacterized protein. (164 aa)
	DAXX	Death domain associated protein. (779 aa)
	EIF2B5	Eukaryotic translation initiation factor 2B subunit epsilon. (720 aa)
	DHX36	DEAH-box helicase 36. (1013 aa)
	HSP90AA1	HATPase_c domain-containing protein. (679 aa)
	NOS1	Nitric oxide synthase 1. (1467 aa)
	TCIM	Transcriptional and immune response regulator. (106 aa)
	HSPA2	Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (635 aa)
	M3Z6U8_MUSPF	Small ubiquitin-related modifier. (100 aa)
	SLC52A3	Solute carrier family 52 member 3. (469 aa)
	M3Z176_MUSPF	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (221 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2552 aa)
	HSPB1	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (207 aa)
	DNAJA3	DnaJ heat shock protein family (Hsp40) member A3. (558 aa)
	NF1	Neurofibromin 1. (2815 aa)
	CASQ1	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (402 aa)
	YWHAE	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (251 aa)
	SLU7	SLU7 homolog, splicing factor. (633 aa)
	IER5L	Immediate early response 5 like. (313 aa)
	HSP90AB1	Heat shock protein 90 alpha family class B member 1. (724 aa)
	HMOX1	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
	TRPV1	Transient receptor potential cation channel subfamily V member 1. (770 aa)
	TPR	Translocated promoter region, nuclear basket protein. (2439 aa)
	IGF1	Insulin like growth factor 1. (153 aa)
	IER5	Immediate early response 5. (299 aa)
	DNAJA4	DnaJ heat shock protein family (Hsp40) member A4. (545 aa)
	PDCD6	Programmed cell death 6. (189 aa)
	CLPB	ClpB homolog, mitochondrial AAA ATPase chaperonin. (709 aa)
	TRPM2	Transient receptor potential cation channel subfamily M member 2. (1496 aa)
	HIKESHI	Heat shock protein nuclear import factor hikeshi. (197 aa)
	TRPV2	Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (766 aa)
	IL1A	Interleukin-1; Belongs to the IL-1 family. (270 aa)
	M3YE80_MUSPF	SHSP domain-containing protein; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (214 aa)
	GCLC	Glutamate-cysteine ligase catalytic subunit. (629 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASIC3	TRPV1	ENSMPUP00000008162	ENSMPUP00000012003	Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	Transient receptor potential cation channel subfamily V member 1.	0.847
ASIC3	TRPV4	ENSMPUP00000008162	ENSMPUP00000003878	Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family.	0.663
BAG3	DNAJA4	ENSMPUP00000003026	ENSMPUP00000010935	BCL2 associated athanogene 3.	DnaJ heat shock protein family (Hsp40) member A4.	0.586
BAG3	HSF1	ENSMPUP00000003026	ENSMPUP00000006650	BCL2 associated athanogene 3.	Heat shock transcription factor 1.	0.681
BAG3	HSP90AB1	ENSMPUP00000003026	ENSMPUP00000012498	BCL2 associated athanogene 3.	Heat shock protein 90 alpha family class B member 1.	0.542
BAG3	HSPA2	ENSMPUP00000003026	ENSMPUP00000019520	BCL2 associated athanogene 3.	Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family.	0.659
BAG3	HSPB1	ENSMPUP00000003026	ENSMPUP00000015889	BCL2 associated athanogene 3.	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family.	0.785
BAG3	HSPB6	ENSMPUP00000003026	ENSMPUP00000006029	BCL2 associated athanogene 3.	Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family.	0.565
BAG3	M3XWY3_MUSPF	ENSMPUP00000003026	ENSMPUP00000003583	BCL2 associated athanogene 3.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.455
BAG3	M3YE80_MUSPF	ENSMPUP00000003026	ENSMPUP00000009637	BCL2 associated athanogene 3.	SHSP domain-containing protein; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.	0.453
CASQ1	PRKACA	ENSMPUP00000013825	ENSMPUP00000003045	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.497
CKM	CLPB	ENSMPUP00000005998	ENSMPUP00000010096	Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family.	ClpB homolog, mitochondrial AAA ATPase chaperonin.	0.694
CLPB	CKM	ENSMPUP00000010096	ENSMPUP00000005998	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family.	0.694
CLPB	DNAJA3	ENSMPUP00000010096	ENSMPUP00000014899	ClpB homolog, mitochondrial AAA ATPase chaperonin.	DnaJ heat shock protein family (Hsp40) member A3.	0.681
CLPB	DNAJA4	ENSMPUP00000010096	ENSMPUP00000010935	ClpB homolog, mitochondrial AAA ATPase chaperonin.	DnaJ heat shock protein family (Hsp40) member A4.	0.559
CLPB	HIKESHI	ENSMPUP00000010096	ENSMPUP00000010071	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Heat shock protein nuclear import factor hikeshi.	0.571
CLPB	HSP90AA1	ENSMPUP00000010096	ENSMPUP00000002744	ClpB homolog, mitochondrial AAA ATPase chaperonin.	HATPase_c domain-containing protein.	0.685
CLPB	HSP90AB1	ENSMPUP00000010096	ENSMPUP00000012498	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Heat shock protein 90 alpha family class B member 1.	0.685
CLPB	HSPA2	ENSMPUP00000010096	ENSMPUP00000019520	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family.	0.709
CLPB	M3XSM2_MUSPF	ENSMPUP00000010096	ENSMPUP00000002072	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Uncharacterized protein.	0.685