STRINGSTRING
NKX6-1 NKX6-1 STAT3 STAT3 SH3TC1 SH3TC1 CNP CNP METRNL METRNL GPR37L1 GPR37L1 EGR2 EGR2 PAX6 PAX6 NOTCH1 NOTCH1 VIM VIM SOX13 SOX13 CNTN2 CNTN2 TAL1 TAL1 LAMC3 LAMC3 MAPK3 MAPK3 ABL1 ABL1 SOX10 SOX10 PICK1 PICK1 EIF2B3 EIF2B3 TREM2 TREM2 TREML1 TREML1 DAG1 DAG1 ITGB4 ITGB4 LAMB2 LAMB2 NCSTN NCSTN MYRF MYRF SH3TC2 SH3TC2 SOX9 SOX9 VTN VTN FGF10 FGF10 NF1 NF1 SUZ12 SUZ12 TRPC4 TRPC4 AKT3 AKT3 NCMAP NCMAP SOX8 SOX8 NKX2-1 NKX2-1 MTOR MTOR FGF2 FGF2 METTL14 METTL14 IFNG IFNG B4GALT5 B4GALT5 KCNJ10 KCNJ10 PRX PRX AKT2 AKT2 SIRT2 SIRT2 MMP24 MMP24 ADGRG6 ADGRG6 TGFB1 TGFB1 GLI3 GLI3 RELN RELN C5AR1 C5AR1 LEF1 LEF1 EIF2B2 EIF2B2 PLP1 PLP1 EIF2B4 EIF2B4 NR2E1 NR2E1 FA2H FA2H AGER AGER TPPP TPPP KRAS KRAS CRB1 CRB1 GFAP GFAP GCM1 GCM1 M3YAG4_MUSPF M3YAG4_MUSPF S100A8 S100A8 CDK5 CDK5 M3YA02_MUSPF M3YA02_MUSPF TENM4 TENM4 EMX1 EMX1 LGI4 LGI4 M3Y711_MUSPF M3Y711_MUSPF DLL1 DLL1 MAG MAG MPP5 MPP5 B4GALT6 B4GALT6 PTPRZ1 PTPRZ1 PRDM8 PRDM8 M3Y503_MUSPF M3Y503_MUSPF BMP2 BMP2 GPR157 GPR157 M3Y4E6_MUSPF M3Y4E6_MUSPF M3Y3U3_MUSPF M3Y3U3_MUSPF ERCC2 ERCC2 SMO SMO GBA GBA ILK ILK SOX4 SOX4 MED12 MED12 DNER DNER NFIB NFIB DUSP10 DUSP10 NRROS NRROS TTC21B TTC21B HES1 HES1 DLX1 DLX1 DLX2 DLX2 ERBB3 ERBB3 NKX2-2 NKX2-2 WASF3 WASF3 M3XQ60_MUSPF M3XQ60_MUSPF OLIG2 OLIG2 S100B S100B CUL4B CUL4B PHGDH PHGDH EIF2B1 EIF2B1 TSPAN2 TSPAN2 TLR4 TLR4 NAB2 NAB2 NDRG1 NDRG1 M3XSS0_MUSPF M3XSS0_MUSPF AKT1 AKT1 NTRK2 NTRK2 EIF2B5 EIF2B5 PTPN11 PTPN11 ARHGEF10 ARHGEF10 MAPK1 MAPK1 GAP43 GAP43 CNTN1 CNTN1 CNTF CNTF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NKX6-1NK6 homeobox 1. (355 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
SH3TC1SH3 domain and tetratricopeptide repeats 1. (1335 aa)
CNP2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family. (420 aa)
METRNLMeteorin like, glial cell differentiation regulator. (254 aa)
GPR37L1G protein-coupled receptor 37 like 1. (470 aa)
EGR2Early growth response 2. (485 aa)
PAX6Paired box 6. (436 aa)
NOTCH1Notch receptor 1. (2119 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
SOX13SRY-box transcription factor 13. (615 aa)
CNTN2Contactin 2. (1077 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (346 aa)
LAMC3Laminin subunit gamma 3. (1516 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
SOX10SRY-box transcription factor 10. (602 aa)
PICK1Protein interacting with PRKCA 1. (417 aa)
EIF2B3Eukaryotic translation initiation factor 2B subunit gamma. (452 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
TREML1Triggering receptor expressed on myeloid cells like 1. (314 aa)
DAG1Dystroglycan 1. (891 aa)
ITGB4Integrin beta. (1803 aa)
LAMB2Laminin subunit beta 2. (1801 aa)
NCSTNNicastrin. (729 aa)
MYRFMyelin regulatory factor. (1150 aa)
SH3TC2SH3 domain and tetratricopeptide repeats 2. (1289 aa)
SOX9SRY-box transcription factor 9. (522 aa)
VTNSMB domain-containing protein. (470 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
NF1Neurofibromin 1. (2815 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (740 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
NCMAPNon-compact myelin associated protein. (176 aa)
SOX8SRY-box transcription factor 8. (377 aa)
NKX2-1NK2 homeobox 1. (371 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2552 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
METTL14Methyltransferase like 14; Belongs to the MT-A70-like family. (459 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
B4GALT5Beta-1,4-galactosyltransferase 5. (344 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (379 aa)
PRXPeriaxin. (1478 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (412 aa)
MMP24Matrix metallopeptidase 24. (574 aa)
ADGRG6Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1195 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
GLI3GLI family zinc finger 3. (1585 aa)
RELNReelin. (3458 aa)
C5AR1Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
LEF1Lymphoid enhancer binding factor 1. (400 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (356 aa)
PLP1Proteolipid protein 1. (242 aa)
EIF2B4Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (523 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
AGERAdvanced glycosylation end-product specific receptor. (400 aa)
TPPPTubulin polymerization promoting protein. (221 aa)
KRASKRAS proto-oncogene, GTPase. (208 aa)
CRB1Crumbs cell polarity complex component 1. (1411 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (457 aa)
GCM1Glial cells missing transcription factor 1. (442 aa)
M3YAG4_MUSPFEF-hand domain-containing protein; Belongs to the S-100 family. (189 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
M3YA02_MUSPFUncharacterized protein. (155 aa)
TENM4Teneurin transmembrane protein 4. (2855 aa)
EMX1Empty spiracles homeobox 1. (207 aa)
LGI4Leucine rich repeat LGI family member 4. (537 aa)
M3Y711_MUSPFacidPPc domain-containing protein. (237 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (602 aa)
MAGMyelin associated glycoprotein. (628 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
B4GALT6Beta-1,4-galactosyltransferase 6. (382 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2325 aa)
PRDM8PR/SET domain 8. (398 aa)
M3Y503_MUSPFHomeobox domain-containing protein. (149 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
GPR157G protein-coupled receptor 157. (326 aa)
M3Y4E6_MUSPFUncharacterized protein. (160 aa)
M3Y3U3_MUSPFUncharacterized protein. (313 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (815 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (790 aa)
GBAGlucosylceramidase. (547 aa)
ILKIntegrin linked kinase. (452 aa)
SOX4SRY-box transcription factor 4. (269 aa)
MED12Mediator complex subunit 12. (2168 aa)
DNERDelta/notch like EGF repeat containing. (643 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
DUSP10Dual specificity phosphatase 10. (482 aa)
NRROSNegative regulator of reactive oxygen species. (707 aa)
TTC21BTetratricopeptide repeat domain 21B. (1316 aa)
HES1Hes family bHLH transcription factor 1. (283 aa)
DLX1Distal-less homeobox 1. (255 aa)
DLX2Distal-less homeobox 2. (332 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1339 aa)
NKX2-2NK2 homeobox 2. (273 aa)
WASF3WASP family member 3. (406 aa)
M3XQ60_MUSPFUncharacterized protein. (47 aa)
OLIG2Oligodendrocyte transcription factor 2. (295 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
CUL4BCullin 4B; Belongs to the cullin family. (1041 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
EIF2B1Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; Belongs to the eIF-2B alpha/beta/delta subunits family. (305 aa)
TSPAN2Tetraspanin. (222 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
NAB2NGFI-A binding protein 2. (525 aa)
NDRG1N-myc downstream regulated 1. (384 aa)
M3XSS0_MUSPFPDZ domain-containing protein. (710 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
NTRK2Neurotrophic receptor tyrosine kinase 2. (477 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (720 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10. (1332 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
GAP43Growth associated protein 43. (242 aa)
CNTN1Contactin 1. (1018 aa)
CNTFCiliary neurotrophic factor. (200 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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