STRINGSTRING
LOC101676600 LOC101676600 CLIC4 CLIC4 SYT10 SYT10 CPNE8 CPNE8 CACNA1H CACNA1H SLC30A2 SLC30A2 MAPK1 MAPK1 GLRA2 GLRA2 SCN5A SCN5A RASAL1 RASAL1 CUTA CUTA DAXX DAXX MAPK3 MAPK3 RYR2 RYR2 RASGRP2 RASGRP2 BAD BAD IQGAP1 IQGAP1 CACNA1G CACNA1G PEF1 PEF1 PRKAA1 PRKAA1 MEF2C MEF2C SYT17 SYT17 M3YPP3_MUSPF M3YPP3_MUSPF M3YTE7_MUSPF M3YTE7_MUSPF SLC30A5 SLC30A5 MTF1 MTF1 CPNE5 CPNE5 M3YRV1_MUSPF M3YRV1_MUSPF SYT7 SYT7 NCSTN NCSTN BNIP3 BNIP3 PKD2 PKD2 HVCN1 HVCN1 P2RX7 P2RX7 P2RX4 P2RX4 FABP4 FABP4 SYT3 SYT3 SLC25A13 SLC25A13 SYT4 SYT4 SLC30A8 SLC30A8 SLC25A12 SLC25A12 STK39 STK39 TFAP2A TFAP2A MAPK9 MAPK9 BMP6 BMP6 CREB1 CREB1 CARF CARF LRRK2 LRRK2 ADCY7 ADCY7 SLC18A2 SLC18A2 BRAF BRAF LOXL2 LOXL2 MT4 MT4 M3XWR1_MUSPF M3XWR1_MUSPF M3XWU8_MUSPF M3XWU8_MUSPF LOC101680925 LOC101680925 SYT12 SYT12 ANXA11 ANXA11 M3Z0I5_MUSPF M3Z0I5_MUSPF ECT2 ECT2 CPNE9 CPNE9 PPIF PPIF AHCYL1 AHCYL1 CHUK CHUK THBS1 THBS1 TRPV6 TRPV6 HFE HFE ITPKA ITPKA M3YC29_MUSPF M3YC29_MUSPF FOS FOS PLCG2 PLCG2 TIGAR TIGAR KHK KHK PPP3CA PPP3CA SLC30A3 SLC30A3 ADAM9 ADAM9 FXN FXN IL1A IL1A CAPN3 CAPN3 CPNE4 CPNE4 TRPM2 TRPM2 PDCD6 PDCD6 SYT9 SYT9 NEK7 NEK7 STIM1 STIM1 DLG4 DLG4 PAM PAM KCNMA1 KCNMA1 DMTN DMTN SLC30A10 SLC30A10 TCIRG1 TCIRG1 CPNE2 CPNE2 ACO1 ACO1 ALOX15 ALOX15 MEF2A MEF2A B2M B2M CPNE3 CPNE3 ADD1 ADD1 TJP1 TJP1 SYT2 SYT2 SLC13A5 SLC13A5 HAAO HAAO M3YJK1_MUSPF M3YJK1_MUSPF CDKN1B CDKN1B TRPC1 TRPC1 SLC41A1 SLC41A1 SLC34A1 SLC34A1 HMOX1 HMOX1 JUN JUN JUND JUND KCNJ10 KCNJ10 ALOX5AP ALOX5AP ITPKB ITPKB CAPN9 CAPN9 GPLD1 GPLD1 CASR CASR HOMER1 HOMER1 M3Y193_MUSPF M3Y193_MUSPF AQP1 AQP1 SYT11 SYT11 M3Z6U8_MUSPF M3Z6U8_MUSPF PRNP PRNP SYT6 SYT6 M3Y280_MUSPF M3Y280_MUSPF CRHBP CRHBP NFATC4 NFATC4 SMPD1 SMPD1 M3Y3P5_MUSPF M3Y3P5_MUSPF SYT8 SYT8 CPNE6 CPNE6 MNAT1 MNAT1 HIF1A HIF1A ACER1 ACER1 PARK7 PARK7 FBP1 FBP1 ALG2 ALG2 HSF1 HSF1 SLC25A23 SLC25A23 GPHN GPHN SMPD3 SMPD3 CAV1 CAV1 PRKAA2 PRKAA2 GLRA1 GLRA1 SYT5 SYT5 DPEP1 DPEP1 CPNE7 CPNE7 LGMN LGMN AOC1 AOC1 M3Y8F4_MUSPF M3Y8F4_MUSPF M3Y830_MUSPF M3Y830_MUSPF M3XLW6_MUSPF M3XLW6_MUSPF JUNB JUNB M3Z3T6_MUSPF M3Z3T6_MUSPF ADCY1 ADCY1 EGFR EGFR ATP7B ATP7B GSS GSS M3Z266_MUSPF M3Z266_MUSPF ITPKC ITPKC KCNMB4 KCNMB4 SYT1 SYT1 TRPC3 TRPC3 KCNMB3 KCNMB3 M3YZI9_MUSPF M3YZI9_MUSPF ABCB6 ABCB6 ATP13A2 ATP13A2 NCF1 NCF1 M3YWZ8_MUSPF M3YWZ8_MUSPF SLC30A1 SLC30A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101676600Homeobox domain-containing protein. (185 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
SYT10Synaptotagmin 10. (523 aa)
CPNE8Copine 8. (577 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2143 aa)
SLC30A2Solute carrier family 30 member 2. (375 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
GLRA2Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
RASAL1RAS protein activator like 1. (813 aa)
CUTACutA divalent cation tolerance homolog. (210 aa)
DAXXDeath domain associated protein. (779 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
RYR2Ryanodine receptor 2. (4966 aa)
RASGRP2RAS guanyl releasing protein 2. (659 aa)
BADBCL2 associated agonist of cell death. (168 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1627 aa)
CACNA1GCalcium voltage-gated channel subunit alpha1 G. (2177 aa)
PEF1Penta-EF-hand domain containing 1. (289 aa)
PRKAA1Non-specific serine/threonine protein kinase. (517 aa)
MEF2CMyocyte enhancer factor 2C. (433 aa)
SYT17Synaptotagmin 17. (474 aa)
M3YPP3_MUSPFUncharacterized protein. (204 aa)
M3YTE7_MUSPFUncharacterized protein. (49 aa)
SLC30A5Solute carrier family 30 member 5. (674 aa)
MTF1Metal regulatory transcription factor 1. (747 aa)
CPNE5Copine 5. (610 aa)
M3YRV1_MUSPFUncharacterized protein. (286 aa)
SYT7Synaptotagmin 7. (611 aa)
NCSTNNicastrin. (729 aa)
BNIP3BCL2 interacting protein 3. (190 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (915 aa)
HVCN1Hydrogen voltage gated channel 1. (271 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (401 aa)
FABP4Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
SYT3Synaptotagmin 3. (638 aa)
SLC25A13Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (675 aa)
SYT4Synaptotagmin 4. (425 aa)
SLC30A8Solute carrier family 30 member 8. (369 aa)
SLC25A12Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (678 aa)
STK39Serine/threonine kinase 39. (546 aa)
TFAP2ATranscription factor AP-2 alpha. (384 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
BMP6Bone morphogenetic protein 6. (426 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CARFCalcium responsive transcription factor. (723 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
SLC18A2Solute carrier family 18 member A2. (517 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (715 aa)
LOXL2Lysyl oxidase like 2. (772 aa)
MT4Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (62 aa)
M3XWR1_MUSPFMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
M3XWU8_MUSPFUncharacterized protein; Belongs to the metallothionein superfamily. Type 1 family. (161 aa)
LOC101680925Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
SYT12Synaptotagmin 12. (421 aa)
ANXA11Annexin. (505 aa)
M3Z0I5_MUSPFKcnmB2_inactiv domain-containing protein. (261 aa)
ECT2Epithelial cell transforming 2. (914 aa)
CPNE9Copine family member 9. (587 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (211 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
THBS1Thrombospondin 1. (1170 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (724 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (403 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
M3YC29_MUSPFUncharacterized protein. (417 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (446 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
KHKKetohexokinase. (408 aa)
PPP3CASerine/threonine-protein phosphatase. (461 aa)
SLC30A3Solute carrier family 30 member 3. (388 aa)
ADAM9ADAM metallopeptidase domain 9. (785 aa)
FXNFrataxin. (155 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (270 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (821 aa)
CPNE4Copine 4. (557 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1496 aa)
PDCD6Programmed cell death 6. (189 aa)
SYT9Synaptotagmin 9. (491 aa)
NEK7NIMA related kinase 7; Belongs to the protein kinase superfamily. (322 aa)
STIM1Stromal interaction molecule 1. (755 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (724 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (963 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1020 aa)
DMTNDematin actin binding protein. (350 aa)
SLC30A10Solute carrier family 30 member 10. (414 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
CPNE2Copine II. (548 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (889 aa)
ALOX15Arachidonate 15-lipoxygenase. (663 aa)
MEF2AMyocyte enhancer factor 2A. (416 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (128 aa)
CPNE3Copine 3. (533 aa)
ADD1Adducin 1. (775 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1770 aa)
SYT2Synaptotagmin 2. (495 aa)
SLC13A5Solute carrier family 13 member 5. (571 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase. (286 aa)
M3YJK1_MUSPFC2 domain-containing protein. (168 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (199 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (743 aa)
SLC41A1Solute carrier family 41 member 1. (514 aa)
SLC34A1Solute carrier family 34 member 1. (639 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (347 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (379 aa)
ALOX5APArachidonate 5-lipoxygenase activating protein. (161 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (938 aa)
CAPN9Calpain 9; Belongs to the peptidase C2 family. (691 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (875 aa)
CASRCalcium sensing receptor. (1082 aa)
HOMER1Homer scaffold protein 1. (354 aa)
M3Y193_MUSPFC2 domain-containing protein. (500 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SYT11Synaptotagmin 11. (431 aa)
M3Z6U8_MUSPFSmall ubiquitin-related modifier. (100 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (257 aa)
SYT6Synaptotagmin 6. (396 aa)
M3Y280_MUSPFUncharacterized protein. (94 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
NFATC4Nuclear factor of activated T cells 4. (831 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa)
M3Y3P5_MUSPFUncharacterized protein. (304 aa)
SYT8Synaptotagmin 8. (391 aa)
CPNE6Copine 6. (655 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (263 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
ALG2ALG2 alpha-1,3/1,6-mannosyltransferase. (419 aa)
HSF1Heat shock transcription factor 1. (555 aa)
SLC25A23Solute carrier family 25 member 23; Belongs to the mitochondrial carrier (TC 2.A.29) family. (436 aa)
GPHNGephyrin. (805 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (658 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
PRKAA2Non-specific serine/threonine protein kinase. (524 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (449 aa)
SYT5Synaptotagmin 5. (386 aa)
DPEP1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (410 aa)
CPNE7Copine 7. (651 aa)
LGMNLegumain. (433 aa)
AOC1Amine oxidase. (756 aa)
M3Y8F4_MUSPFUncharacterized protein. (174 aa)
M3Y830_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (417 aa)
M3XLW6_MUSPFUncharacterized protein. (97 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
M3Z3T6_MUSPFHomeobox domain-containing protein. (184 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1130 aa)
EGFRReceptor protein-tyrosine kinase. (1207 aa)
ATP7BATPase copper transporting beta. (1495 aa)
GSSGlutathione synthetase. (474 aa)
M3Z266_MUSPFC2 domain-containing protein. (537 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (667 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
SYT1Synaptotagmin 1. (422 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (866 aa)
KCNMB3Potassium calcium-activated channel subfamily M regulatory beta subunit 3. (285 aa)
M3YZI9_MUSPFHomeobox domain-containing protein. (197 aa)
ABCB6ATP binding cassette subfamily B member 6 (Langereis blood group). (842 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1173 aa)
NCF1Neutrophil cytosolic factor 1. (391 aa)
M3YWZ8_MUSPFUncharacterized protein. (839 aa)
SLC30A1Solute carrier family 30 member 1. (505 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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