(12 nodes) Specification of animal organ identity network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GLI3	GLI family zinc finger 3. (1585 aa)
	AXIN2	Axin 2. (842 aa)
	TBR1	T-box brain transcription factor 1. (682 aa)
	LRP2	LDL receptor related protein 2. (4699 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	FOXH1	Forkhead box H1. (398 aa)
	MEF2C	Myocyte enhancer factor 2C. (433 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (441 aa)
	PAX8	Paired box 8. (462 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	BMP4	ENSMPUP00000014547	ENSMPUP00000005423	Axin 2.	Bone morphogenetic protein 4.	0.552
AXIN2	LRP2	ENSMPUP00000014547	ENSMPUP00000000737	Axin 2.	LDL receptor related protein 2.	0.451
AXIN2	WNT11	ENSMPUP00000014547	ENSMPUP00000008719	Axin 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.615
BMP4	AXIN2	ENSMPUP00000005423	ENSMPUP00000014547	Bone morphogenetic protein 4.	Axin 2.	0.552
BMP4	FGF10	ENSMPUP00000005423	ENSMPUP00000014301	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.818
BMP4	WNT11	ENSMPUP00000005423	ENSMPUP00000008719	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.418
FGF10	BMP4	ENSMPUP00000014301	ENSMPUP00000005423	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.818
FOXH1	TBR1	ENSMPUP00000006078	ENSMPUP00000000545	Forkhead box H1.	T-box brain transcription factor 1.	0.417
LRP2	AXIN2	ENSMPUP00000000737	ENSMPUP00000014547	LDL receptor related protein 2.	Axin 2.	0.451
TBR1	FOXH1	ENSMPUP00000000545	ENSMPUP00000006078	T-box brain transcription factor 1.	Forkhead box H1.	0.417
WNT11	AXIN2	ENSMPUP00000008719	ENSMPUP00000014547	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Axin 2.	0.615
WNT11	BMP4	ENSMPUP00000008719	ENSMPUP00000005423	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Bone morphogenetic protein 4.	0.418