STRINGSTRING
PINK1 PINK1 TRIM65 TRIM65 WDR45 WDR45 LRSAM1 LRSAM1 SVIP SVIP SNX18 SNX18 WIPI1 WIPI1 PRKAA1 PRKAA1 ZC3H12A ZC3H12A WAC WAC PIP4K2B PIP4K2B M3YUJ9_MUSPF M3YUJ9_MUSPF FYCO1 FYCO1 CALCOCO2 CALCOCO2 TSC2 TSC2 M3YVM5_MUSPF M3YVM5_MUSPF SESN2 SESN2 C9orf72 C9orf72 WDR24 WDR24 NPRL3 NPRL3 SCOC SCOC VPS13D VPS13D RUFY4 RUFY4 TRIM8 TRIM8 IFNG IFNG TBK1 TBK1 SUPT5H SUPT5H TP53INP2 TP53INP2 TRIM13 TRIM13 M3Z3D8_MUSPF M3Z3D8_MUSPF TRIM32 TRIM32 PLEKHF1 PLEKHF1 FLCN FLCN SMCR8 SMCR8 M3XM17_MUSPF M3XM17_MUSPF LRRK2 LRRK2 RALB RALB OPTN OPTN M3XPS6_MUSPF M3XPS6_MUSPF TRIML1 TRIML1 BTNL9 BTNL9 TRIM27 TRIM27 UFL1 UFL1 PIP4K2C PIP4K2C DAPK1 DAPK1 ULK1 ULK1 BNIP3 BNIP3 SH3BP4 SH3BP4 RAB3GAP1 RAB3GAP1 TPCN1 TPCN1 BAG3 BAG3 NOD2 NOD2 SNX7 SNX7 ATF6 ATF6 MID2 MID2 RAB3GAP2 RAB3GAP2 SNX4 SNX4 PAFAH1B2 PAFAH1B2 M3XZP3_MUSPF M3XZP3_MUSPF M3XZQ7_MUSPF M3XZQ7_MUSPF M3XZR5_MUSPF M3XZR5_MUSPF SH3GLB1 SH3GLB1 NOD1 NOD1 KDR KDR ATG16L1 ATG16L1 PRKD1 PRKD1 ROCK1 ROCK1 ATG13 ATG13 AMBRA1 AMBRA1 M3Y2G4_MUSPF M3Y2G4_MUSPF CCNY CCNY HIF1A HIF1A TMEM59 TMEM59 M3Y5U4_MUSPF M3Y5U4_MUSPF RB1CC1 RB1CC1 PRKAA2 PRKAA2 DCN DCN M3Y830_MUSPF M3Y830_MUSPF ATG101 ATG101 SNX30 SNX30 STK11 STK11 MTDH MTDH TRIM38 TRIM38 SPTLC2 SPTLC2 TP53INP1 TP53INP1 STING1 STING1 M3YEF8_MUSPF M3YEF8_MUSPF FOXO3 FOXO3 SESN1 SESN1 M3YF39_MUSPF M3YF39_MUSPF M3YF42_MUSPF M3YF42_MUSPF TRIM6 TRIM6 BECN1 BECN1 IL4 IL4 TRIM21 TRIM21 TRIM68 TRIM68 HTT HTT RIPK2 RIPK2 KAT5 KAT5 SIRT1 SIRT1 PIP4K2A PIP4K2A SESN3 SESN3 FBXO7 FBXO7 HMOX1 HMOX1 ATG2A ATG2A MAPK3 MAPK3 M3YMV5_MUSPF M3YMV5_MUSPF ENDOG ENDOG NPRL2 NPRL2 CDK16 CDK16 LARP1 LARP1 TFEB TFEB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PINK1PTEN induced kinase 1. (580 aa)
TRIM65Tripartite motif containing 65. (517 aa)
WDR45Uncharacterized protein. (441 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (727 aa)
SVIPSmall VCP interacting protein. (96 aa)
SNX18Sorting nexin. (624 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (479 aa)
PRKAA1Non-specific serine/threonine protein kinase. (517 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (576 aa)
WACWW domain containing adaptor with coiled-coil. (601 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (363 aa)
M3YUJ9_MUSPFHMG box domain-containing protein. (171 aa)
FYCO1FYVE and coiled-coil domain containing 1. (1441 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (495 aa)
TSC2TSC complex subunit 2. (1906 aa)
M3YVM5_MUSPFTLC domain-containing protein. (267 aa)
SESN2Sestrin 2. (479 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
WDR24WD repeat domain 24. (790 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (569 aa)
SCOCShort coiled-coil protein. (160 aa)
VPS13DVacuolar protein sorting 13 homolog D. (4389 aa)
RUFY4RUN and FYVE domain containing 4. (544 aa)
TRIM8Tripartite motif containing 8. (551 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
TBK1TANK-binding kinase 1. (729 aa)
SUPT5HSPT5 homolog, DSIF elongation factor subunit. (1087 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (224 aa)
TRIM13Tripartite motif containing 13. (394 aa)
M3Z3D8_MUSPFAminotran_1_2 domain-containing protein. (213 aa)
TRIM32Tripartite motif containing 32. (673 aa)
PLEKHF1Pleckstrin homology and FYVE domain containing 1. (285 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
SMCR8SMCR8-C9orf72 complex subunit. (937 aa)
M3XM17_MUSPFUncharacterized protein. (208 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
RALBRAS like proto-oncogene B. (206 aa)
OPTNOptineurin. (586 aa)
M3XPS6_MUSPFB box-type domain-containing protein. (115 aa)
TRIML1Tripartite motif family like 1. (455 aa)
BTNL9Butyrophilin like 9. (542 aa)
TRIM27Tripartite motif containing 27. (516 aa)
UFL1UFM1 specific ligase 1. (792 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa)
DAPK1Death associated protein kinase 1. (1430 aa)
ULK1Unc-51 like autophagy activating kinase 1. (970 aa)
BNIP3BCL2 interacting protein 3. (190 aa)
SH3BP4SH3 domain binding protein 4. (962 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (985 aa)
TPCN1Two pore segment channel 1. (861 aa)
BAG3BCL2 associated athanogene 3. (597 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1013 aa)
SNX7Sorting nexin 7. (474 aa)
ATF6Activating transcription factor 6. (659 aa)
MID2Midline 2. (716 aa)
RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2. (1393 aa)
SNX4Sorting nexin 4. (450 aa)
PAFAH1B2Platelet activating factor acetylhydrolase 1b catalytic subunit 2. (229 aa)
M3XZP3_MUSPFHMG box domain-containing protein. (215 aa)
M3XZQ7_MUSPFUbiquitin-like domain-containing protein. (311 aa)
M3XZR5_MUSPFRBR-type E3 ubiquitin transferase. (115 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (401 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (952 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
ATG16L1Autophagy related 16 like 1. (623 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (824 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1252 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1209 aa)
M3Y2G4_MUSPFUncharacterized protein. (50 aa)
CCNYCyclin Y; Belongs to the cyclin family. (341 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
TMEM59Transmembrane protein 59. (320 aa)
M3Y5U4_MUSPFAminotran_1_2 domain-containing protein. (469 aa)
RB1CC1RB1 inducible coiled-coil 1. (1593 aa)
PRKAA2Non-specific serine/threonine protein kinase. (524 aa)
DCNDecorin; May affect the rate of fibrils formation. (360 aa)
M3Y830_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (417 aa)
ATG101Autophagy related 101. (218 aa)
SNX30Sorting nexin family member 30. (437 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (443 aa)
MTDHMetadherin. (627 aa)
TRIM38Tripartite motif containing 38. (522 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (561 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (239 aa)
STING1Transmembrane protein 173. (378 aa)
M3YEF8_MUSPFFOXO-TAD domain-containing protein. (399 aa)
FOXO3Forkhead box O3. (671 aa)
SESN1Sestrin 1. (551 aa)
M3YF39_MUSPFUncharacterized protein. (296 aa)
M3YF42_MUSPFUncharacterized protein. (487 aa)
TRIM6Tripartite motif containing 6. (486 aa)
BECN1Beclin 1. (448 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (132 aa)
TRIM21Tripartite motif containing 21. (468 aa)
TRIM68Tripartite motif containing 68. (485 aa)
HTTHuntingtin. (3018 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
SIRT1Sirtuin 1. (557 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (368 aa)
SESN3Sestrin 3. (495 aa)
FBXO7F-box protein 7. (444 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
ATG2AAutophagy related 2A. (1930 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
M3YMV5_MUSPFDEP domain-containing protein. (1704 aa)
ENDOGEndonuclease. (237 aa)
NPRL2NPR2 like, GATOR1 complex subunit. (380 aa)
CDK16Cyclin dependent kinase 16; Belongs to the protein kinase superfamily. (500 aa)
LARP1La ribonucleoprotein domain family member 1. (907 aa)
TFEBTranscription factor EB. (478 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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