STRINGSTRING
MAP2K4 MAP2K4 MYOCD MYOCD BAG3 BAG3 RBM10 RBM10 NKX2-5 NKX2-5 IGF1 IGF1 SIRT1 SIRT1 DIPK2A DIPK2A PPP1R10 PPP1R10 LRP6 LRP6 ALOX12 ALOX12 M3YEN4_MUSPF M3YEN4_MUSPF ATG5 ATG5 TIGAR TIGAR TP53 TP53 APOH APOH ZC3H12A ZC3H12A PDPK1 PDPK1 KIFAP3 KIFAP3 MFN2 MFN2 IFNG IFNG CCDC142 CCDC142 LYPD3 LYPD3 DNMT1 DNMT1 PDCD4 PDCD4 HAND2 HAND2 M3YPM9_MUSPF M3YPM9_MUSPF NOL3 NOL3 SFRP2 SFRP2 FNDC1 FNDC1 E2F3 E2F3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP2K4Mitogen-activated protein kinase kinase 4. (281 aa)
MYOCDMyocardin. (980 aa)
BAG3BCL2 associated athanogene 3. (597 aa)
RBM10RNA binding motif protein 10. (1060 aa)
NKX2-5NK2 homeobox 5. (323 aa)
IGF1Insulin like growth factor 1. (153 aa)
SIRT1Sirtuin 1. (557 aa)
DIPK2ADivergent protein kinase domain 2A. (430 aa)
PPP1R10Protein phosphatase 1 regulatory subunit 10. (956 aa)
LRP6LDL receptor related protein 6. (1462 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (663 aa)
M3YEN4_MUSPFBZIP domain-containing protein. (358 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
APOHApolipoprotein H. (345 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (576 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
KIFAP3Kinesin associated protein 3. (793 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
CCDC142Coiled-coil domain containing 142. (768 aa)
LYPD3LY6/PLAUR domain containing 3. (344 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1674 aa)
PDCD4Programmed cell death 4. (469 aa)
HAND2Heart and neural crest derivatives expressed 2. (208 aa)
M3YPM9_MUSPFBZIP domain-containing protein. (351 aa)
NOL3Nucleolar protein 3. (217 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
FNDC1Fibronectin type III domain containing 1. (1906 aa)
E2F3E2F transcription factor 3. (340 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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