STRINGSTRING
ATG5 ATG5 TIGAR TIGAR KIFAP3 KIFAP3 HAND2 HAND2 MYOCD MYOCD FNDC1 FNDC1 SFRP2 SFRP2 NOL3 NOL3 TP53 TP53 PDPK1 PDPK1 NKX2-5 NKX2-5 PPP1R10 PPP1R10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
KIFAP3Kinesin associated protein 3. (793 aa)
HAND2Heart and neural crest derivatives expressed 2. (208 aa)
MYOCDMyocardin. (980 aa)
FNDC1Fibronectin type III domain containing 1. (1906 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
NOL3Nucleolar protein 3. (217 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
NKX2-5NK2 homeobox 5. (323 aa)
PPP1R10Protein phosphatase 1 regulatory subunit 10. (956 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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