STRINGSTRING
GPER1 GPER1 EPM2AIP1 EPM2AIP1 DYRK2 DYRK2 GCK GCK M3Z3A6_MUSPF M3Z3A6_MUSPF AKT2 AKT2 PPP1R3C PPP1R3C FOXK1 FOXK1 EP300 EP300 M3YXD0_MUSPF M3YXD0_MUSPF AKT3 AKT3 PDK2 PDK2 COX11 COX11 M3YUN0_MUSPF M3YUN0_MUSPF USP7 USP7 IGFBP4 IGFBP4 ENPP1 ENPP1 ZMPSTE24 ZMPSTE24 DDB1 DDB1 C1QTNF12 C1QTNF12 PPP1R3F PPP1R3F GIT1 GIT1 MST1 MST1 INPP5K INPP5K GNMT GNMT M3YP04_MUSPF M3YP04_MUSPF M3YP02_MUSPF M3YP02_MUSPF PTH PTH BAD BAD C1QTNF6 C1QTNF6 C1QTNF1 C1QTNF1 WDR5 WDR5 CRY1 CRY1 AVPR1B AVPR1B PRKCE PRKCE IGF1 IGF1 SIRT1 SIRT1 SLC45A3 SLC45A3 IER3 IER3 BCKDK BCKDK M3YJ43_MUSPF M3YJ43_MUSPF GCGR GCGR DGKQ DGKQ ADIPOR1 ADIPOR1 LHR LHR M3YHM7_MUSPF M3YHM7_MUSPF ACADM ACADM RANBP2 RANBP2 NCOA2 NCOA2 M3YGT2_MUSPF M3YGT2_MUSPF POU1F1 POU1F1 KAT2A KAT2A STAT3 STAT3 NCOR1 NCOR1 M3YEF8_MUSPF M3YEF8_MUSPF P2RY6 P2RY6 M3YE86_MUSPF M3YE86_MUSPF KHK KHK SLC4A1 SLC4A1 TIGAR TIGAR MLYCD MLYCD TFF3 TFF3 TP53 TP53 MIDN MIDN SCARB2 SCARB2 INSR INSR PPP1R3A PPP1R3A CBFA2T3 CBFA2T3 FAM3C FAM3C PPP1R3E PPP1R3E FBP1 FBP1 IGF2 IGF2 INS INS OGT OGT GPLD1 GPLD1 SIRT6 SIRT6 M3XZR5_MUSPF M3XZR5_MUSPF M3XZQ7_MUSPF M3XZQ7_MUSPF PTPN2 PTPN2 SLC35B4 SLC35B4 DDIT4 DDIT4 DUSP12 DUSP12 ADIPOQ ADIPOQ SERPINA12 SERPINA12 ACTN3 ACTN3 AKT1 AKT1 PDK4 PDK4 RUBCNL RUBCNL ZNF692 ZNF692 PTK2B PTK2B PDK1 PDK1 RORA RORA LEPR LEPR PASK PASK HDAC4 HDAC4 ERFE ERFE PDK3 PDK3 FLCN FLCN PPP1R3D PPP1R3D PPP1R3B PPP1R3B MAS1 MAS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
EPM2AIP1EPM2A interacting protein 1. (608 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (528 aa)
GCKPhosphotransferase. (473 aa)
M3Z3A6_MUSPFThyroglobulin type-1 domain-containing protein. (186 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (316 aa)
FOXK1Forkhead box K1. (614 aa)
EP300E1A binding protein p300. (2425 aa)
M3YXD0_MUSPFFork-head domain-containing protein. (575 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
PDK2Protein-serine/threonine kinase. (482 aa)
COX11Cytochrome c oxidase copper chaperone COX11. (279 aa)
M3YUN0_MUSPFC1q domain-containing protein. (306 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1055 aa)
IGFBP4Insulin like growth factor binding protein 4. (279 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (847 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
DDB1Damage specific DNA binding protein 1. (1114 aa)
C1QTNF12C1q and TNF related 12. (305 aa)
PPP1R3FProtein phosphatase 1 regulatory subunit 3F. (813 aa)
GIT1GIT ArfGAP 1. (708 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (711 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (473 aa)
GNMTGlycine N-methyltransferase. (226 aa)
M3YP04_MUSPFUncharacterized protein. (675 aa)
M3YP02_MUSPFPCAF_N domain-containing protein. (92 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
BADBCL2 associated agonist of cell death. (168 aa)
C1QTNF6C1q and TNF related 6. (265 aa)
C1QTNF1C1q and TNF related 1. (331 aa)
WDR5WD repeat domain 5. (334 aa)
CRY1Cryptochrome circadian regulator 1. (587 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
IGF1Insulin like growth factor 1. (153 aa)
SIRT1Sirtuin 1. (557 aa)
SLC45A3Solute carrier family 45 member 3. (552 aa)
IER3Immediate early response 3. (155 aa)
BCKDKProtein-serine/threonine kinase. (412 aa)
M3YJ43_MUSPFLeucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (339 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (488 aa)
DGKQDiacylglycerol kinase. (952 aa)
ADIPOR1Adiponectin receptor 1. (375 aa)
LHRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (692 aa)
M3YHM7_MUSPFFork-head domain-containing protein. (528 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (421 aa)
RANBP2RAN binding protein 2. (2857 aa)
NCOA2DUF1518 domain-containing protein. (1226 aa)
M3YGT2_MUSPFUncharacterized protein. (219 aa)
POU1F1POU domain protein. (357 aa)
KAT2ALysine acetyltransferase 2A. (869 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
NCOR1Nuclear receptor corepressor 1. (2510 aa)
M3YEF8_MUSPFFOXO-TAD domain-containing protein. (399 aa)
P2RY6Pyrimidinergic receptor P2Y6. (395 aa)
M3YE86_MUSPFUncharacterized protein. (766 aa)
KHKKetohexokinase. (408 aa)
SLC4A1Anion exchange protein. (924 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
MLYCDMalonyl-CoA decarboxylase. (316 aa)
TFF3Trefoil factor 3. (80 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
MIDNMidnolin. (460 aa)
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (478 aa)
INSRTyrosine-protein kinase receptor. (1352 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1117 aa)
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (630 aa)
FAM3CFamily with sequence similarity 3 member C. (227 aa)
PPP1R3EProtein phosphatase 1 regulatory subunit 3E. (279 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
IGF2Insulin like growth factor 2. (192 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (109 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1047 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (875 aa)
SIRT6Sirtuin 6. (359 aa)
M3XZR5_MUSPFRBR-type E3 ubiquitin transferase. (115 aa)
M3XZQ7_MUSPFUbiquitin-like domain-containing protein. (311 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (388 aa)
SLC35B4Solute carrier family 35 member B4. (330 aa)
DDIT4DNA damage inducible transcript 4. (230 aa)
DUSP12Dual specificity phosphatase 12. (340 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
SERPINA12Serpin family A member 12; Belongs to the serpin family. (414 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (904 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PDK4Protein-serine/threonine kinase. (412 aa)
RUBCNLRubicon like autophagy enhancer. (656 aa)
ZNF692Zinc finger protein 692. (514 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
PDK1Protein-serine/threonine kinase. (378 aa)
RORARAR related orphan receptor A. (430 aa)
LEPRLeptin receptor. (1164 aa)
PASKPAS domain containing serine/threonine kinase. (1341 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1083 aa)
ERFEErythroferrone. (402 aa)
PDK3Protein-serine/threonine kinase. (415 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
PPP1R3DProtein phosphatase 1 regulatory subunit. (299 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (284 aa)
MAS1MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: low (16%) [HD]