STRINGSTRING
ITGB1 ITGB1 GNA12 GNA12 TGFB1 TGFB1 FGF2 FGF2 APPL1 APPL1 RCC2 RCC2 GNA13 GNA13 SLC9A3R1 SLC9A3R1 ITGB1BP1 ITGB1BP1 CLN3 CLN3 APPL2 APPL2 PRKCE PRKCE PRR5L PRR5L ENSMPUP00000009823 ENSMPUP00000009823 BAG4 BAG4 THBS1 THBS1 M3Y9K9_MUSPF M3Y9K9_MUSPF WDPCP WDPCP AQP1 AQP1 DMTN DMTN DDR2 DDR2 M3XWE1_MUSPF M3XWE1_MUSPF BRAF BRAF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
GNA12G protein subunit alpha 12. (305 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (672 aa)
RCC2Regulator of chromosome condensation 2. (427 aa)
GNA13G protein subunit alpha 13. (284 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
CLN3Battenin. (438 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (660 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
PRR5LProline rich 5 like. (368 aa)
ENSMPUP00000009823annotation not available (94 aa)
BAG4BCL2 associated athanogene 4. (457 aa)
THBS1Thrombospondin 1. (1170 aa)
M3Y9K9_MUSPFIntegrin beta; Belongs to the integrin beta chain family. (645 aa)
WDPCPWD repeat containing planar cell polarity effector. (714 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
DMTNDematin actin binding protein. (350 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (924 aa)
M3XWE1_MUSPFCoronin; Belongs to the WD repeat coronin family. (474 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (715 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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