(14 nodes) Regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum network (Mustela putorius)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	TRDN	Triadin. (664 aa)
	TMEM38A	Transmembrane protein 38A. (303 aa)
	M3Z785_MUSPF	Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
	CASQ2	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (505 aa)
	CHD7	Chromodomain helicase DNA binding protein 7. (2522 aa)
	HRC	Histidine rich calcium binding protein. (711 aa)
	CALM3	Calmodulin 3; Belongs to the calmodulin family. (151 aa)
	TMEM38B	Transmembrane protein 38B. (291 aa)
	DHRS7C	Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa)
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (156 aa)
	CALM2	Calmodulin 2; Belongs to the calmodulin family. (149 aa)
	RYR2	Ryanodine receptor 2. (4966 aa)
	CASQ1	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (402 aa)
	FKBP1B	Peptidylprolyl isomerase. (209 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALM1	FKBP1B	ENSMPUP00000008029	ENSMPUP00000013836	Calmodulin 1; Belongs to the calmodulin family.	Peptidylprolyl isomerase.	0.879
CALM1	M3Z785_MUSPF	ENSMPUP00000008029	ENSMPUP00000019448	Calmodulin 1; Belongs to the calmodulin family.	Uncharacterized protein; Belongs to the calmodulin family.	0.701
CALM1	RYR2	ENSMPUP00000008029	ENSMPUP00000012626	Calmodulin 1; Belongs to the calmodulin family.	Ryanodine receptor 2.	0.944
CALM2	CASQ2	ENSMPUP00000011969	ENSMPUP00000001648	Calmodulin 2; Belongs to the calmodulin family.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.442
CALM2	FKBP1B	ENSMPUP00000011969	ENSMPUP00000013836	Calmodulin 2; Belongs to the calmodulin family.	Peptidylprolyl isomerase.	0.879
CALM2	M3Z785_MUSPF	ENSMPUP00000011969	ENSMPUP00000019448	Calmodulin 2; Belongs to the calmodulin family.	Uncharacterized protein; Belongs to the calmodulin family.	0.701
CALM2	RYR2	ENSMPUP00000011969	ENSMPUP00000012626	Calmodulin 2; Belongs to the calmodulin family.	Ryanodine receptor 2.	0.949
CALM3	FKBP1B	ENSMPUP00000005223	ENSMPUP00000013836	Calmodulin 3; Belongs to the calmodulin family.	Peptidylprolyl isomerase.	0.880
CALM3	M3Z785_MUSPF	ENSMPUP00000005223	ENSMPUP00000019448	Calmodulin 3; Belongs to the calmodulin family.	Uncharacterized protein; Belongs to the calmodulin family.	0.701
CALM3	RYR2	ENSMPUP00000005223	ENSMPUP00000012626	Calmodulin 3; Belongs to the calmodulin family.	Ryanodine receptor 2.	0.959
CASQ1	CASQ2	ENSMPUP00000013825	ENSMPUP00000001648	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.917
CASQ1	FKBP1B	ENSMPUP00000013825	ENSMPUP00000013836	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Peptidylprolyl isomerase.	0.488
CASQ1	HRC	ENSMPUP00000013825	ENSMPUP00000003009	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Histidine rich calcium binding protein.	0.479
CASQ1	RYR2	ENSMPUP00000013825	ENSMPUP00000012626	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 2.	0.981
CASQ1	TRDN	ENSMPUP00000013825	ENSMPUP00000014372	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Triadin.	0.991
CASQ2	CALM2	ENSMPUP00000001648	ENSMPUP00000011969	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Calmodulin 2; Belongs to the calmodulin family.	0.442
CASQ2	CASQ1	ENSMPUP00000001648	ENSMPUP00000013825	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.917
CASQ2	FKBP1B	ENSMPUP00000001648	ENSMPUP00000013836	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Peptidylprolyl isomerase.	0.503
CASQ2	HRC	ENSMPUP00000001648	ENSMPUP00000003009	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Histidine rich calcium binding protein.	0.500
CASQ2	RYR2	ENSMPUP00000001648	ENSMPUP00000012626	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 2.	0.996