Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABRAXAS1 | ATM | ENSMPUP00000014568 | ENSMPUP00000005920 | Abraxas 1, BRCA1 A complex subunit. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.569 |
| ABRAXAS1 | BABAM1 | ENSMPUP00000014568 | ENSMPUP00000015803 | Abraxas 1, BRCA1 A complex subunit. | BRISC and BRCA1 A complex member 1. | 0.999 |
| ABRAXAS1 | BABAM2 | ENSMPUP00000014568 | ENSMPUP00000017879 | Abraxas 1, BRCA1 A complex subunit. | BRISC and BRCA1 A complex member 2. | 0.998 |
| ABRAXAS1 | BRCC3 | ENSMPUP00000014568 | ENSMPUP00000016027 | Abraxas 1, BRCA1 A complex subunit. | BRCA1/BRCA2-containing complex subunit 3. | 0.999 |
| ABRAXAS1 | CHEK2 | ENSMPUP00000014568 | ENSMPUP00000013463 | Abraxas 1, BRCA1 A complex subunit. | Checkpoint kinase 2. | 0.676 |
| ABRAXAS1 | M3Y878_MUSPF | ENSMPUP00000014568 | ENSMPUP00000007535 | Abraxas 1, BRCA1 A complex subunit. | Uncharacterized protein. | 0.692 |
| ABRAXAS1 | MRE11 | ENSMPUP00000014568 | ENSMPUP00000012153 | Abraxas 1, BRCA1 A complex subunit. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.734 |
| ABRAXAS1 | NBN | ENSMPUP00000014568 | ENSMPUP00000010920 | Abraxas 1, BRCA1 A complex subunit. | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. | 0.706 |
| ABRAXAS1 | TP53BP1 | ENSMPUP00000014568 | ENSMPUP00000010187 | Abraxas 1, BRCA1 A complex subunit. | Tumor protein p53 binding protein 1. | 0.574 |
| ABRAXAS1 | UIMC1 | ENSMPUP00000014568 | ENSMPUP00000012202 | Abraxas 1, BRCA1 A complex subunit. | Ubiquitin interaction motif containing 1. | 0.998 |
| AFMID | BIRC5 | ENSMPUP00000013153 | ENSMPUP00000013150 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Baculoviral IAP repeat containing 5. | 0.407 |
| APBB2 | ATM | ENSMPUP00000006140 | ENSMPUP00000005920 | Amyloid beta precursor protein binding family B member 2. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.422 |
| APBB2 | MRE11 | ENSMPUP00000006140 | ENSMPUP00000012153 | Amyloid beta precursor protein binding family B member 2. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.495 |
| APBB2 | NBN | ENSMPUP00000006140 | ENSMPUP00000010920 | Amyloid beta precursor protein binding family B member 2. | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. | 0.438 |
| ATF5 | EIF2AK4 | ENSMPUP00000002274 | ENSMPUP00000008237 | Activating transcription factor 5. | Eukaryotic translation initiation factor 2 alpha kinase 4. | 0.456 |
| ATM | ABRAXAS1 | ENSMPUP00000005920 | ENSMPUP00000014568 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Abraxas 1, BRCA1 A complex subunit. | 0.569 |
| ATM | APBB2 | ENSMPUP00000005920 | ENSMPUP00000006140 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Amyloid beta precursor protein binding family B member 2. | 0.422 |
| ATM | ATR | ENSMPUP00000005920 | ENSMPUP00000011930 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.998 |
| ATM | ATRIP | ENSMPUP00000005920 | ENSMPUP00000014819 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | ATR interacting protein. | 0.885 |
| ATM | ATRX | ENSMPUP00000005920 | ENSMPUP00000000083 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | ATRX chromatin remodeler. | 0.615 |
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