STRINGSTRING
M3XMU8_MUSPF M3XMU8_MUSPF SEPTIN2 SEPTIN2 SYT10 SYT10 LRRK2 LRRK2 M3XNH8_MUSPF M3XNH8_MUSPF RAB8B RAB8B RAPGEF4 RAPGEF4 SYT4 SYT4 SYT3 SYT3 BLK BLK ADRA2A ADRA2A RAB27A RAB27A SYTL4 SYTL4 RPH3A RPH3A PFN2 PFN2 IL1RAPL1 IL1RAPL1 M3XU94_MUSPF M3XU94_MUSPF STXBP3 STXBP3 BCR BCR GIPC1 GIPC1 CACNA1A CACNA1A BRAF BRAF SYT12 SYT12 DRD2 DRD2 SPHK2 SPHK2 M3XXR2_MUSPF M3XXR2_MUSPF LGI3 LGI3 DGKI DGKI GIPC3 GIPC3 CHRM2 CHRM2 M3XY67_MUSPF M3XY67_MUSPF SNX4 SNX4 BACE1 BACE1 TPCN2 TPCN2 M3XZQ7_MUSPF M3XZQ7_MUSPF M3XZR5_MUSPF M3XZR5_MUSPF REST REST RAB12 RAB12 RAP1A RAP1A SYT11 SYT11 SYT6 SYT6 DTNBP1 DTNBP1 F2RL1 F2RL1 RAB3D RAB3D NCKAP1L NCKAP1L EXPH5 EXPH5 M3Y3P5_MUSPF M3Y3P5_MUSPF M3Y3R5_MUSPF M3Y3R5_MUSPF SYT8 SYT8 KLRK1 KLRK1 RAB15 RAB15 CADPS2 CADPS2 M3Y653_MUSPF M3Y653_MUSPF CD177 CD177 GRIN3A GRIN3A RAB3B RAB3B CFTR CFTR M3Y7C1_MUSPF M3Y7C1_MUSPF RAB3C RAB3C SYT5 SYT5 AP1G1 AP1G1 SLC4A8 SLC4A8 M3Y931_MUSPF M3Y931_MUSPF M3YA21_MUSPF M3YA21_MUSPF CHMP2A CHMP2A SNAPIN SNAPIN CDK5 CDK5 GSK3B GSK3B FOXF1 FOXF1 CBARP CBARP VPS18 VPS18 ANXA1 ANXA1 M3YC29_MUSPF M3YC29_MUSPF VAMP8 VAMP8 C12orf4 C12orf4 CNR1 CNR1 APBA1 APBA1 LAMP1 LAMP1 MICAL1 MICAL1 SYT9 SYT9 LYN LYN IL13 IL13 GIPC2 GIPC2 CHRNA5 CHRNA5 SYT2 SYT2 NOTCH1 NOTCH1 HGS HGS M3YJK1_MUSPF M3YJK1_MUSPF STAM STAM STX1B STX1B CACNB2 CACNB2 PREPL PREPL PRKCB PRKCB RAB24 RAB24 M3YLM3_MUSPF M3YLM3_MUSPF DOC2A DOC2A RAC2 RAC2 PLA2G3 PLA2G3 IL4R IL4R HYAL3 HYAL3 RAB5A RAB5A DNM1 DNM1 SYT17 SYT17 CACNA1I CACNA1I DOC2B DOC2B SDC1 SDC1 RPH3AL RPH3AL TSG101 TSG101 UNC13D UNC13D STXBP1 STXBP1 SYP SYP GIT1 GIT1 SYT7 SYT7 KIAA0100 KIAA0100 M3YS01_MUSPF M3YS01_MUSPF DVL1 DVL1 M3YTP8_MUSPF M3YTP8_MUSPF FBXL20 FBXL20 CSPG5 CSPG5 M3YUE8_MUSPF M3YUE8_MUSPF RIMS2 RIMS2 CACNA1B CACNA1B M3YV15_MUSPF M3YV15_MUSPF PDPK1 PDPK1 SNF8 SNF8 RAB26 RAB26 FGR FGR FES FES BAIAP3 BAIAP3 RAB3A RAB3A CACNA1H CACNA1H ZP3 ZP3 RAB8A RAB8A STX1A STX1A M3YXE6_MUSPF M3YXE6_MUSPF RAB33B RAB33B M3YXN1_MUSPF M3YXN1_MUSPF ATP13A2 ATP13A2 RAB27B RAB27B VPS4B VPS4B M3YZQ2_MUSPF M3YZQ2_MUSPF SYNPR SYNPR M3Z0F8_MUSPF M3Z0F8_MUSPF NLGN1 NLGN1 SCAMP5 SCAMP5 SYT1 SYT1 RAP1B RAP1B ATP9A ATP9A STXBP5 STXBP5 RALA RALA ADCY1 ADCY1 PCLO PCLO RAB9A RAB9A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M3XMU8_MUSPFSH3 domain-containing protein. (473 aa)
SEPTIN2Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (361 aa)
SYT10Synaptotagmin 10. (523 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
M3XNH8_MUSPFUncharacterized protein. (132 aa)
RAB8BRAB8B, member RAS oncogene family. (207 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1011 aa)
SYT4Synaptotagmin 4. (425 aa)
SYT3Synaptotagmin 3. (638 aa)
BLKTyrosine-protein kinase. (500 aa)
ADRA2AAdrenoceptor alpha 2A; Belongs to the G-protein coupled receptor 1 family. (323 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
SYTL4Synaptotagmin like 4. (671 aa)
RPH3ARabphilin 3A. (702 aa)
PFN2Profilin; Belongs to the profilin family. (191 aa)
IL1RAPL1Interleukin 1 receptor accessory protein like 1. (413 aa)
M3XU94_MUSPFUncharacterized protein. (170 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (512 aa)
BCRBCR activator of RhoGEF and GTPase. (1279 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2496 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (715 aa)
SYT12Synaptotagmin 12. (421 aa)
DRD2D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (443 aa)
SPHK2Sphingosine kinase 2. (673 aa)
M3XXR2_MUSPFSeptin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (322 aa)
LGI3Leucine rich repeat LGI family member 3. (548 aa)
DGKIDiacylglycerol kinase. (999 aa)
GIPC3GIPC PDZ domain containing family member 3. (252 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (496 aa)
M3XY67_MUSPFDouble C2-like domain-containing protein. (383 aa)
SNX4Sorting nexin 4. (450 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (505 aa)
TPCN2Uncharacterized protein. (746 aa)
M3XZQ7_MUSPFUbiquitin-like domain-containing protein. (311 aa)
M3XZR5_MUSPFRBR-type E3 ubiquitin transferase. (115 aa)
RESTRE1 silencing transcription factor. (1098 aa)
RAB12RAB12, member RAS oncogene family. (186 aa)
RAP1ARAP1A, member of RAS oncogene family. (188 aa)
SYT11Synaptotagmin 11. (431 aa)
SYT6Synaptotagmin 6. (396 aa)
DTNBP1Dystrobrevin binding protein 1. (349 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
RAB3DRAB3D, member RAS oncogene family. (219 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
EXPH5Exophilin 5. (1998 aa)
M3Y3P5_MUSPFUncharacterized protein. (304 aa)
M3Y3R5_MUSPFUncharacterized protein. (137 aa)
SYT8Synaptotagmin 8. (391 aa)
KLRK1Killer cell lectin like receptor K1. (191 aa)
RAB15RAB15, member RAS oncogene family. (177 aa)
CADPS2Calcium dependent secretion activator 2. (1159 aa)
M3Y653_MUSPFProtein kinase domain-containing protein. (212 aa)
CD177CD177 molecule. (443 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1135 aa)
RAB3BRAB3B, member RAS oncogene family. (219 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1484 aa)
M3Y7C1_MUSPFUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
RAB3CRAB3C, member RAS oncogene family. (227 aa)
SYT5Synaptotagmin 5. (386 aa)
AP1G1AP-1 complex subunit gamma. (814 aa)
SLC4A8Anion exchange protein. (1133 aa)
M3Y931_MUSPFUncharacterized protein. (203 aa)
M3YA21_MUSPFWD_REPEATS_REGION domain-containing protein. (467 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
FOXF1Forkhead box F1. (321 aa)
CBARPCACN subunit beta associated regulatory protein. (552 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (973 aa)
ANXA1Annexin. (345 aa)
M3YC29_MUSPFUncharacterized protein. (417 aa)
VAMP8Vesicle associated membrane protein 8. (111 aa)
C12orf4Chromosome 12 open reading frame 4. (552 aa)
CNR1Cannabinoid receptor 1; Belongs to the G-protein coupled receptor 1 family. (411 aa)
APBA1Amyloid beta precursor protein binding family A member 1. (832 aa)
LAMP1Lysosomal associated membrane protein 1. (388 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1076 aa)
SYT9Synaptotagmin 9. (491 aa)
LYNTyrosine-protein kinase. (512 aa)
IL13Interleukin 13. (128 aa)
GIPC2GIPC PDZ domain containing family member 2. (312 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (511 aa)
SYT2Synaptotagmin 2. (495 aa)
NOTCH1Notch receptor 1. (2119 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (780 aa)
M3YJK1_MUSPFC2 domain-containing protein. (168 aa)
STAMSignal transducing adaptor molecule. (520 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (294 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (523 aa)
PREPLProlyl endopeptidase like. (727 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (577 aa)
RAB24RAB24, member RAS oncogene family. (209 aa)
M3YLM3_MUSPFV-SNARE coiled-coil homology domain-containing protein. (496 aa)
DOC2ADouble C2 domain alpha. (416 aa)
RAC2Rac family small GTPase 2. (192 aa)
PLA2G3Phospholipase A2 group III. (510 aa)
IL4RInterleukin 4 receptor. (805 aa)
HYAL3Hyaluronidase. (415 aa)
RAB5ARAB5A, member RAS oncogene family. (215 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
SYT17Synaptotagmin 17. (474 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2024 aa)
DOC2BDouble C2 domain beta. (376 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (295 aa)
RPH3ALRabphilin 3A like (without C2 domains). (301 aa)
TSG101Tumor susceptibility 101. (391 aa)
UNC13DUnc-13 homolog D. (1091 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (594 aa)
SYPSynaptophysin. (314 aa)
GIT1GIT ArfGAP 1. (708 aa)
SYT7Synaptotagmin 7. (611 aa)
KIAA0100KIAA0100. (2231 aa)
M3YS01_MUSPFIg-like domain-containing protein. (306 aa)
DVL1Dishevelled segment polarity protein 1. (691 aa)
M3YTP8_MUSPFV-SNARE coiled-coil homology domain-containing protein. (122 aa)
FBXL20F-box and leucine rich repeat protein 20. (423 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (399 aa)
M3YUE8_MUSPFLongin domain-containing protein; Belongs to the synaptobrevin family. (110 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1458 aa)
CACNA1BCalcium voltage-gated channel subunit alpha1 B. (1971 aa)
M3YV15_MUSPFSeptin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (1004 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
RAB26RAB26, member RAS oncogene family. (255 aa)
FGRTyrosine-protein kinase. (526 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (820 aa)
BAIAP3BAI1 associated protein 3. (1157 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2143 aa)
ZP3Zona pellucida glycoprotein C. (426 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (259 aa)
M3YXE6_MUSPFUncharacterized protein; Belongs to the synaptobrevin family. (220 aa)
RAB33BRAB33B, member RAS oncogene family. (229 aa)
M3YXN1_MUSPFUncharacterized protein. (506 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1173 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (422 aa)
M3YZQ2_MUSPFUncharacterized protein. (1262 aa)
SYNPRSynaptoporin. (265 aa)
M3Z0F8_MUSPFCOesterase domain-containing protein. (269 aa)
NLGN1Neuroligin 1. (607 aa)
SCAMP5Secretory carrier-associated membrane protein. (235 aa)
SYT1Synaptotagmin 1. (422 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
ATP9APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1027 aa)
STXBP5Syntaxin binding protein 5. (997 aa)
RALARAS like proto-oncogene A. (206 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1130 aa)
PCLOPiccolo presynaptic cytomatrix protein. (4560 aa)
RAB9ARAB9A, member RAS oncogene family. (201 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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