STRINGSTRING
FBXL2 FBXL2 SMTNL1 SMTNL1 BOD1L1 BOD1L1 FLT4 FLT4 PHACTR1 PHACTR1 JAK1 JAK1 RACK1 RACK1 STAT6 STAT6 SHOC2 SHOC2 ANAPC5 ANAPC5 ANAPC7 ANAPC7 PPP6R2 PPP6R2 VRK3 VRK3 TRAF3 TRAF3 ANKLE2 ANKLE2 PPP1R15A PPP1R15A PPP3CB PPP3CB M3XYF5_MUSPF M3XYF5_MUSPF PPP6R3 PPP6R3 SNX12 SNX12 ENSA ENSA SKAP2 SKAP2 CDH5 CDH5 CTTNBP2NL CTTNBP2NL KCNQ1 KCNQ1 STRN4 STRN4 AP3B1 AP3B1 STRN3 STRN3 AMBRA1 AMBRA1 M3Y2X7_MUSPF M3Y2X7_MUSPF PPP1R16A PPP1R16A M3Y4B5_MUSPF M3Y4B5_MUSPF CLEC12B CLEC12B FAM71F1 FAM71F1 FAM71F2 FAM71F2 GTF2F1 GTF2F1 KCNN4 KCNN4 STX17 STX17 PPP1R3E PPP1R3E CD22 CD22 PHACTR3 PHACTR3 MET MET DAB2IP DAB2IP PPP1R11 PPP1R11 FBXO41 FBXO41 PPP6R1 PPP6R1 PPP1R3A PPP1R3A SH3RF2 SH3RF2 CDC27 CDC27 LRRD1 LRRD1 C20orf27 C20orf27 TP53 TP53 EIF2AK3 EIF2AK3 PPME1 PPME1 M3YEF8_MUSPF M3YEF8_MUSPF SNX3 SNX3 STRN STRN STAT3 STAT3 M3YGX4_MUSPF M3YGX4_MUSPF PDLIM4 PDLIM4 JUP JUP TRAF2 TRAF2 MYO16 MYO16 SMTNL2 SMTNL2 MFHAS1 MFHAS1 CTNNB1 CTNNB1 ATP2B4 ATP2B4 CDKN1B CDKN1B M3YK20_MUSPF M3YK20_MUSPF PPP1R10 PPP1R10 MASTL MASTL MVP MVP M3YMP2_MUSPF M3YMP2_MUSPF PTPA PTPA BAD BAD MTMR3 MTMR3 SPHK1 SPHK1 YWHAE YWHAE GRB2 GRB2 CSF1R CSF1R PPP1R3F PPP1R3F ROS1 ROS1 ITGA1 ITGA1 PIK3R1 PIK3R1 MAP3K5 MAP3K5 FBXL20 FBXL20 SKAP1 SKAP1 MTMR4 MTMR4 PPP1R9B PPP1R9B PHACTR4 PHACTR4 KIFAP3 KIFAP3 AP3B2 AP3B2 IQGAP1 IQGAP1 SLC9A1 SLC9A1 M3YWA8_MUSPF M3YWA8_MUSPF JAK3 JAK3 NEK2 NEK2 STYXL1 STYXL1 ANAPC4 ANAPC4 PPP1R3C PPP1R3C M3Z176_MUSPF M3Z176_MUSPF PAWR PAWR TBK1 TBK1 PPP1R16B PPP1R16B GNA12 GNA12 M3Z2M9_MUSPF M3Z2M9_MUSPF M3Z2N1_MUSPF M3Z2N1_MUSPF EGFR EGFR TCTEX1D4 TCTEX1D4 M3Z4Z6_MUSPF M3Z4Z6_MUSPF AKAP5 AKAP5 PPP1R3B PPP1R3B PPP1R3D PPP1R3D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FBXL2F-box and leucine rich repeat protein 2. (423 aa)
SMTNL1Smoothelin like 1. (454 aa)
BOD1L1Biorientation of chromosomes in cell division 1 like 1. (2989 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
PHACTR1Phosphatase and actin regulator. (648 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
RACK1WD_REPEATS_REGION domain-containing protein. (317 aa)
STAT6Signal transducer and activator of transcription. (844 aa)
SHOC2SHOC2 leucine rich repeat scaffold protein. (582 aa)
ANAPC5Anaphase promoting complex subunit 5. (711 aa)
ANAPC7Anaphase promoting complex subunit 7. (598 aa)
PPP6R2Protein phosphatase 6 regulatory subunit 2. (978 aa)
VRK3VRK serine/threonine kinase 3. (455 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
ANKLE2Ankyrin repeat and LEM domain containing 2. (900 aa)
PPP1R15AProtein phosphatase 1 regulatory subunit 15A. (593 aa)
PPP3CBSerine/threonine-protein phosphatase. (479 aa)
M3XYF5_MUSPFUncharacterized protein. (341 aa)
PPP6R3Protein phosphatase 6 regulatory subunit 3. (873 aa)
SNX12Sorting nexin 12. (172 aa)
ENSAEndosulfine alpha; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (117 aa)
SKAP2Src kinase associated phosphoprotein 2. (359 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa)
CTTNBP2NLCTTNBP2 N-terminal like. (642 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (590 aa)
STRN4Striatin 4. (708 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1090 aa)
STRN3Striatin 3. (750 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1209 aa)
M3Y2X7_MUSPFGalectin. (287 aa)
PPP1R16AProtein phosphatase 1 regulatory subunit 16A. (526 aa)
M3Y4B5_MUSPFC-type lectin domain-containing protein. (309 aa)
CLEC12BC-type lectin domain family 12 member B. (225 aa)
FAM71F1Family with sequence similarity 71 member F1. (344 aa)
FAM71F2Family with sequence similarity 71 member F2. (309 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
KCNN4Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4. (429 aa)
STX17Syntaxin 17; Belongs to the syntaxin family. (302 aa)
PPP1R3EProtein phosphatase 1 regulatory subunit 3E. (279 aa)
CD22CD22 molecule. (858 aa)
PHACTR3Phosphatase and actin regulator. (586 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1540 aa)
DAB2IPDAB2 interacting protein. (1112 aa)
PPP1R11Protein phosphatase 1 regulatory inhibitor subunit 11. (126 aa)
FBXO41F-box protein 41. (816 aa)
PPP6R1Protein phosphatase 6 regulatory subunit 1. (937 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1117 aa)
SH3RF2SH3 domain containing ring finger 2. (733 aa)
CDC27Cell division cycle 27. (825 aa)
LRRD1Leucine rich repeats and death domain containing 1. (869 aa)
C20orf27Chromosome 20 open reading frame 27. (180 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1065 aa)
PPME1Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. (386 aa)
M3YEF8_MUSPFFOXO-TAD domain-containing protein. (399 aa)
SNX3Sorting nexin 3. (162 aa)
STRNStriatin. (808 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
M3YGX4_MUSPFUncharacterized protein. (369 aa)
PDLIM4PDZ and LIM domain 4. (331 aa)
JUPJunction plakoglobin. (744 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
MYO16Myosin XVI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1789 aa)
SMTNL2Smoothelin like 2. (449 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1052 aa)
CTNNB1Catenin beta 1. (781 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1206 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (199 aa)
M3YK20_MUSPFWD_REPEATS_REGION domain-containing protein. (237 aa)
PPP1R10Protein phosphatase 1 regulatory subunit 10. (956 aa)
MASTLMicrotubule associated serine/threonine kinase like. (787 aa)
MVPMajor vault protein. (998 aa)
M3YMP2_MUSPFUncharacterized protein. (185 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (288 aa)
BADBCL2 associated agonist of cell death. (168 aa)
MTMR3Myotubularin related protein 3. (1211 aa)
SPHK1Sphingosine kinase 1. (386 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (251 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa)
PPP1R3FProtein phosphatase 1 regulatory subunit 3F. (813 aa)
ROS1Tyrosine-protein kinase receptor. (2342 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1398 aa)
FBXL20F-box and leucine rich repeat protein 20. (423 aa)
SKAP1Src kinase associated phosphoprotein 1. (363 aa)
MTMR4Myotubularin related protein 4. (1146 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (820 aa)
PHACTR4Phosphatase and actin regulator. (708 aa)
KIFAP3Kinesin associated protein 3. (793 aa)
AP3B2AP-3 complex subunit beta. (1083 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1627 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
M3YWA8_MUSPFUncharacterized protein. (726 aa)
JAK3Tyrosine-protein kinase. (1107 aa)
NEK2NIMA related kinase 2. (444 aa)
STYXL1Serine/threonine/tyrosine interacting like 1. (307 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (807 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (316 aa)
M3Z176_MUSPF14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (221 aa)
PAWRPro-apoptotic WT1 regulator. (360 aa)
TBK1TANK-binding kinase 1. (729 aa)
PPP1R16BProtein phosphatase 1 regulatory subunit 16B. (568 aa)
GNA12G protein subunit alpha 12. (305 aa)
M3Z2M9_MUSPFUncharacterized protein. (288 aa)
M3Z2N1_MUSPFUncharacterized protein. (385 aa)
EGFRReceptor protein-tyrosine kinase. (1207 aa)
TCTEX1D4Tctex1 domain containing 4. (219 aa)
M3Z4Z6_MUSPFGalectin. (248 aa)
AKAP5A-kinase anchoring protein 5. (429 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (284 aa)
PPP1R3DProtein phosphatase 1 regulatory subunit. (299 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.