(11 nodes) Signal transduction involved in regulation of gene expression network (Mustela putorius)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	PDGFRA	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1087 aa)
	HNF4A	Hepatocyte nuclear factor 4 alpha. (443 aa)
	M3YFM7_MUSPF	SEFIR domain-containing protein. (557 aa)
	SOX17	SRY-box transcription factor 17. (406 aa)
	TBX6	T-box transcription factor 6. (436 aa)
	M3YCY6_MUSPF	SEFIR domain-containing protein. (532 aa)
	MSX1	Msh homeobox 1. (303 aa)
	TRAF5	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
	TRAF2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
	GSC	Goosecoid homeobox. (256 aa)
	PAX6	Paired box 6. (436 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GSC	HNF4A	ENSMPUP00000003106	ENSMPUP00000017557	Goosecoid homeobox.	Hepatocyte nuclear factor 4 alpha.	0.445
HNF4A	GSC	ENSMPUP00000017557	ENSMPUP00000003106	Hepatocyte nuclear factor 4 alpha.	Goosecoid homeobox.	0.445
M3YCY6_MUSPF	TRAF2	ENSMPUP00000009193	ENSMPUP00000010903	SEFIR domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.488
M3YCY6_MUSPF	TRAF5	ENSMPUP00000009193	ENSMPUP00000015743	SEFIR domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.603
M3YFM7_MUSPF	TRAF2	ENSMPUP00000010134	ENSMPUP00000010903	SEFIR domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.488
M3YFM7_MUSPF	TRAF5	ENSMPUP00000010134	ENSMPUP00000015743	SEFIR domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.603
MSX1	SOX17	ENSMPUP00000007891	ENSMPUP00000010429	Msh homeobox 1.	SRY-box transcription factor 17.	0.422
PAX6	PDGFRA	ENSMPUP00000011203	ENSMPUP00000005771	Paired box 6.	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	0.446
PAX6	SOX17	ENSMPUP00000011203	ENSMPUP00000010429	Paired box 6.	SRY-box transcription factor 17.	0.822
PDGFRA	PAX6	ENSMPUP00000005771	ENSMPUP00000011203	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	Paired box 6.	0.446
PDGFRA	SOX17	ENSMPUP00000005771	ENSMPUP00000010429	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	SRY-box transcription factor 17.	0.525
SOX17	MSX1	ENSMPUP00000010429	ENSMPUP00000007891	SRY-box transcription factor 17.	Msh homeobox 1.	0.422
SOX17	PAX6	ENSMPUP00000010429	ENSMPUP00000011203	SRY-box transcription factor 17.	Paired box 6.	0.822
SOX17	PDGFRA	ENSMPUP00000010429	ENSMPUP00000005771	SRY-box transcription factor 17.	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	0.525
SOX17	TBX6	ENSMPUP00000010429	ENSMPUP00000012492	SRY-box transcription factor 17.	T-box transcription factor 6.	0.537
TBX6	SOX17	ENSMPUP00000012492	ENSMPUP00000010429	T-box transcription factor 6.	SRY-box transcription factor 17.	0.537
TRAF2	M3YCY6_MUSPF	ENSMPUP00000010903	ENSMPUP00000009193	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	SEFIR domain-containing protein.	0.488
TRAF2	M3YFM7_MUSPF	ENSMPUP00000010903	ENSMPUP00000010134	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	SEFIR domain-containing protein.	0.488
TRAF2	TRAF5	ENSMPUP00000010903	ENSMPUP00000015743	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.945
TRAF5	M3YCY6_MUSPF	ENSMPUP00000015743	ENSMPUP00000009193	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	SEFIR domain-containing protein.	0.603