STRINGSTRING
SLC25A38 SLC25A38 PTPN11 PTPN11 RCOR1 RCOR1 M3XU69_MUSPF M3XU69_MUSPF PRDX3 PRDX3 ALAS2 ALAS2 BCL6 BCL6 CSF1 CSF1 NRROS NRROS DMTN DMTN CD109 CD109 TCIRG1 TCIRG1 PTPN2 PTPN2 LBR LBR CCL19 CCL19 KLF1 KLF1 DNASE2 DNASE2 SNX10 SNX10 ZBTB7A ZBTB7A HCLS1 HCLS1 JAK2 JAK2 KCNQ1 KCNQ1 CD81 CD81 JAGN1 JAGN1 PML PML IFNG IFNG TGFB1 TGFB1 ZFP36 ZFP36 SRC SRC NCOA6 NCOA6 IKZF1 IKZF1 KMT2E KMT2E JUNB JUNB CITED2 CITED2 CEBPG CEBPG GPR183 GPR183 TOB2 TOB2 GPR68 GPR68 SOCS1 SOCS1 GP9 GP9 CBFB CBFB BMP4 BMP4 F2RL1 F2RL1 GBA GBA PDE1B PDE1B NCKAP1L NCKAP1L KAT6A KAT6A M3Y377_MUSPF M3Y377_MUSPF ERCC2 ERCC2 M3Y3R7_MUSPF M3Y3R7_MUSPF KIT KIT ARID4A ARID4A CLEC1B CLEC1B ETV2 ETV2 IL25 IL25 CEBPE CEBPE M3Y631_MUSPF M3Y631_MUSPF DLL1 DLL1 ADAR ADAR ACTN1 ACTN1 TRIM10 TRIM10 IL31RA IL31RA CEBPA CEBPA KITLG KITLG CBFA2T3 CBFA2T3 IRF4 IRF4 MEF2C MEF2C LYAR LYAR WDR1 WDR1 CALCR CALCR C15orf41 C15orf41 M3YA03_MUSPF M3YA03_MUSPF ZBTB46 ZBTB46 FLI1 FLI1 IRF8 IRF8 SBNO2 SBNO2 LEF1 LEF1 BATF BATF FOS FOS TET2 TET2 HSPA9 HSPA9 SLC4A1 SLC4A1 ATP6AP1 ATP6AP1 PKNOX1 PKNOX1 G6PD G6PD OSTM1 OSTM1 NCAPG2 NCAPG2 UBA5 UBA5 SMAD5 SMAD5 EPB42 EPB42 DYRK3 DYRK3 LYN LYN STAT5B STAT5B M3YHM6_MUSPF M3YHM6_MUSPF M3YHN0_MUSPF M3YHN0_MUSPF M3YHN1_MUSPF M3YHN1_MUSPF M3YHN2_MUSPF M3YHN2_MUSPF ADD1 ADD1 IREB2 IREB2 CASP3 CASP3 MPIG6B MPIG6B FASN FASN MAEA MAEA IAPP IAPP AHSP AHSP TNF TNF MFHAS1 MFHAS1 KAT8 KAT8 CSF2 CSF2 TRAF6 TRAF6 SIRT1 SIRT1 EPAS1 EPAS1 PIP4K2A PIP4K2A ABI1 ABI1 ABCB10 ABCB10 TAL1 TAL1 ADGRF5 ADGRF5 BATF2 BATF2 MYH9 MYH9 M3YMK1_MUSPF M3YMK1_MUSPF M3YMK5_MUSPF M3YMK5_MUSPF GPC3 GPC3 VEGFA VEGFA PAFAH1B1 PAFAH1B1 SRF SRF BATF3 BATF3 THOC5 THOC5 FLVCR1 FLVCR1 JMJD6 JMJD6 TREM2 TREM2 GATA1 GATA1 TREML1 TREML1 TSPO2 TSPO2 TCTA TCTA GLO1 GLO1 SP3 SP3 ITGB8 ITGB8 CSF1R CSF1R M3YSJ7_MUSPF M3YSJ7_MUSPF NF1 NF1 PLA2G10 PLA2G10 L3MBTL3 L3MBTL3 CCR7 CCR7 PIK3R1 PIK3R1 M3YU90_MUSPF M3YU90_MUSPF DCSTAMP DCSTAMP CDK5RAP3 CDK5RAP3 HOXB7 HOXB7 WASF2 WASF2 M3YW95_MUSPF M3YW95_MUSPF M3YW97_MUSPF M3YW97_MUSPF CIB1 CIB1 EPO EPO JAK3 JAK3 CDKN2B CDKN2B CDKN2A CDKN2A IL15 IL15 GAB3 GAB3 SRP54 SRP54 EPHA2 EPHA2 GATA3 GATA3 EP300 EP300 JUN JUN TNFRSF11A TNFRSF11A EIF2AK1 EIF2AK1 PTPN6 PTPN6 CD4 CD4 LTBR LTBR MITF MITF NKX2-3 NKX2-3 FOXP1 FOXP1 DHRS7B DHRS7B FARP2 FARP2 CASP10 CASP10 CASP8 CASP8 CREB1 CREB1 TMEM14C TMEM14C M3XPU3_MUSPF M3XPU3_MUSPF NOTCH2 NOTCH2 RB1 RB1 UFL1 UFL1 TSPAN2 TSPAN2 TNFSF11 TNFSF11 CCN4 CCN4 M3XSC6_MUSPF M3XSC6_MUSPF M3XSY7_MUSPF M3XSY7_MUSPF M3XSY8_MUSPF M3XSY8_MUSPF
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC25A38Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (304 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
RCOR1REST corepressor 1. (376 aa)
M3XU69_MUSPFPirin domain-containing protein; Belongs to the pirin family. (174 aa)
PRDX3Peroxiredoxin 3. (284 aa)
ALAS25-aminolevulinate synthase. (586 aa)
BCL6BCL6 transcription repressor. (706 aa)
CSF1Colony stimulating factor 1. (517 aa)
NRROSNegative regulator of reactive oxygen species. (707 aa)
DMTNDematin actin binding protein. (350 aa)
CD109CD109 molecule. (1448 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (388 aa)
LBRLamin B receptor. (618 aa)
CCL19C-C motif chemokine. (108 aa)
KLF1Kruppel like factor 1. (381 aa)
DNASE2Deoxyribonuclease 2, lysosomal. (393 aa)
SNX10Sorting nexin 10. (201 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (550 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (474 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (590 aa)
CD81Tetraspanin. (287 aa)
JAGN1Jagunal homolog 1. (183 aa)
PMLPromyelocytic leukemia. (876 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
ZFP36ZFP36 ring finger protein. (327 aa)
SRCTyrosine-protein kinase. (536 aa)
NCOA6Nuclear receptor coactivator 6. (1966 aa)
IKZF1IKAROS family zinc finger 1. (528 aa)
KMT2ELysine methyltransferase 2E. (1860 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
CEBPGCCAAT enhancer binding protein gamma. (146 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (356 aa)
TOB2Transducer of ERBB2, 2. (339 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (360 aa)
SOCS1Suppressor of cytokine signaling 1. (216 aa)
GP9Glycoprotein IX platelet. (177 aa)
CBFBCore-binding factor subunit beta. (182 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
GBAGlucosylceramidase. (547 aa)
PDE1BPhosphodiesterase. (535 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1754 aa)
M3Y377_MUSPFNTR domain-containing protein. (233 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (815 aa)
M3Y3R7_MUSPFUncharacterized protein. (144 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (948 aa)
ARID4AAT-rich interaction domain 4A. (1257 aa)
CLEC1BC-type lectin domain family 1 member B. (284 aa)
ETV2ETS variant 2. (344 aa)
IL25Interleukin 25. (169 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
M3Y631_MUSPFRRM domain-containing protein. (540 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (602 aa)
ADARAdenosine deaminase RNA specific. (1166 aa)
ACTN1Actinin alpha 1. (914 aa)
TRIM10Tripartite motif containing 10. (486 aa)
IL31RAInterleukin 31 receptor A. (724 aa)
CEBPACCAAT/enhancer-binding protein. (268 aa)
KITLGKIT ligand. (274 aa)
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (630 aa)
IRF4Interferon regulatory factor 4. (451 aa)
MEF2CMyocyte enhancer factor 2C. (433 aa)
LYARLy1 antibody reactive. (387 aa)
WDR1WD repeat domain 1. (629 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (504 aa)
C15orf41Chromosome 15 open reading frame 41. (281 aa)
M3YA03_MUSPFUncharacterized protein. (666 aa)
ZBTB46Zinc finger and BTB domain containing 46. (590 aa)
FLI1Fli-1 proto-oncogene, ETS transcription factor. (452 aa)
IRF8Interferon regulatory factor 8. (427 aa)
SBNO2Strawberry notch homolog 2. (1081 aa)
LEF1Lymphoid enhancer binding factor 1. (400 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (446 aa)
TET2Tet methylcytosine dioxygenase 2. (2004 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
SLC4A1Anion exchange protein. (924 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (464 aa)
PKNOX1PBX/knotted 1 homeobox 1. (436 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (545 aa)
OSTM1Osteoclastogenesis associated transmembrane protein 1. (334 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1138 aa)
UBA5Ubiquitin like modifier activating enzyme 5. (404 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
EPB42Erythrocyte membrane protein band 4.2. (692 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (587 aa)
LYNTyrosine-protein kinase. (512 aa)
STAT5BSignal transducer and activator of transcription. (691 aa)
M3YHM6_MUSPFANK_REP_REGION domain-containing protein. (264 aa)
M3YHN0_MUSPFUncharacterized protein. (221 aa)
M3YHN1_MUSPFRoc domain-containing protein. (313 aa)
M3YHN2_MUSPFProtein kinase domain-containing protein. (625 aa)
ADD1Adducin 1. (775 aa)
IREB2Iron responsive element binding protein 2. (1010 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
MPIG6BMegakaryocyte and platelet inhibitory receptor G6b. (241 aa)
FASNFatty acid synthase. (2309 aa)
MAEAMacrophage erythroblast attacher. (434 aa)
IAPPIslet amyloid polypeptide. (89 aa)
AHSPAlpha hemoglobin stabilizing protein. (92 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1052 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (461 aa)
CSF2Colony stimulating factor 2. (148 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
SIRT1Sirtuin 1. (557 aa)
EPAS1Endothelial PAS domain protein 1. (868 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (368 aa)
ABI1Abl interactor 1. (507 aa)
ABCB10ATP binding cassette subfamily B member 10. (566 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (346 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1386 aa)
BATF2Basic leucine zipper ATF-like transcription factor 2. (275 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1717 aa)
M3YMK1_MUSPFProtein kinase domain-containing protein. (105 aa)
M3YMK5_MUSPFProtein kinase domain-containing protein. (185 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (398 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
SRFSerum response factor. (508 aa)
BATF3Basic leucine zipper ATF-like transcription factor 3. (122 aa)
THOC5THO complex 5. (683 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (556 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (414 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
GATA1GATA binding protein 1. (414 aa)
TREML1Triggering receptor expressed on myeloid cells like 1. (314 aa)
TSPO2Translocator protein 2. (171 aa)
TCTAT-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. (106 aa)
GLO1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (184 aa)
SP3Sp3 transcription factor. (695 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa)
M3YSJ7_MUSPFPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
NF1Neurofibromin 1. (2815 aa)
PLA2G10Phospholipase A(2). (159 aa)
L3MBTL3L3MBTL histone methyl-lysine binding protein 3. (780 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
M3YU90_MUSPFMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (616 aa)
DCSTAMPDendrocyte expressed seven transmembrane protein. (440 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (504 aa)
HOXB7Homeobox B7. (217 aa)
WASF2WASP family member 2. (498 aa)
M3YW95_MUSPFUncharacterized protein. (139 aa)
M3YW97_MUSPFUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (265 aa)
CIB1Calcium and integrin binding 1. (187 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
JAK3Tyrosine-protein kinase. (1107 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (131 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (152 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
GAB3GRB2 associated binding protein 3. (549 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
EPHA2EPH receptor A2. (975 aa)
GATA3GATA binding protein 3. (444 aa)
EP300E1A binding protein p300. (2425 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
TNFRSF11ATNF receptor superfamily member 11a. (603 aa)
EIF2AK1Eukaryotic translation initiation factor 2 alpha kinase 1. (531 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
CD4CD4. (462 aa)
LTBRLymphotoxin beta receptor. (420 aa)
MITFMelanocyte inducing transcription factor. (520 aa)
NKX2-3NK2 homeobox 3. (281 aa)
FOXP1Forkhead box P1. (676 aa)
DHRS7BDehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1062 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (545 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (484 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
TMEM14CTransmembrane protein 14C. (114 aa)
M3XPU3_MUSPFUncharacterized protein; Belongs to the protein kinase superfamily. (361 aa)
NOTCH2Notch receptor 2. (2471 aa)
RB1RB transcriptional corepressor 1. (948 aa)
UFL1UFM1 specific ligase 1. (792 aa)
TSPAN2Tetraspanin. (222 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa)
CCN4Cellular communication network factor 4. (367 aa)
M3XSC6_MUSPFUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (596 aa)
M3XSY7_MUSPFUncharacterized protein. (242 aa)
M3XSY8_MUSPFUncharacterized protein. (300 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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