66 items (Mustela putorius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (277 aa)
	G6PD	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (545 aa)
	NCAPG2	Non-SMC condensin II complex subunit G2. (1138 aa)
	UBA5	Ubiquitin like modifier activating enzyme 5. (404 aa)
	SMAD5	Mothers against decapentaplegic homolog. (465 aa)
	EPB42	Erythrocyte membrane protein band 4.2. (692 aa)
	DYRK3	Dual specificity tyrosine phosphorylation regulated kinase 3. (587 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	STAT5B	Signal transducer and activator of transcription. (691 aa)
	ADD1	Adducin 1. (775 aa)
	MPIG6B	Megakaryocyte and platelet inhibitory receptor G6b. (241 aa)
	MAEA	Macrophage erythroblast attacher. (434 aa)
	AHSP	Alpha hemoglobin stabilizing protein. (92 aa)
	MFHAS1	Malignant fibrous histiocytoma amplified sequence 1. (1052 aa)
	EPAS1	Endothelial PAS domain protein 1. (868 aa)
	ABCB10	ATP binding cassette subfamily B member 10. (566 aa)
	TAL1	TAL bHLH transcription factor 1, erythroid differentiation factor. (346 aa)
	ADGRF5	Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1386 aa)
	SRF	Serum response factor. (508 aa)
	FLVCR1	Feline leukemia virus subgroup C cellular receptor 1. (556 aa)
	JMJD6	Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (414 aa)
	GATA1	GATA binding protein 1. (414 aa)
	TSPO2	Translocator protein 2. (171 aa)
	SP3	Sp3 transcription factor. (695 aa)
	PLA2G10	Phospholipase A(2). (159 aa)
	L3MBTL3	L3MBTL histone methyl-lysine binding protein 3. (780 aa)
	M3YU90_MUSPF	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (616 aa)
	CDK5RAP3	CDK5 regulatory subunit associated protein 3. (504 aa)
	EPO	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
	JAK3	Tyrosine-protein kinase. (1107 aa)
	GATA3	GATA binding protein 3. (444 aa)
	IKZF1	IKAROS family zinc finger 1. (528 aa)
	KMT2E	Lysine methyltransferase 2E. (1860 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
	CEBPG	CCAAT enhancer binding protein gamma. (146 aa)
	PKNOX1	PBX/knotted 1 homeobox 1. (436 aa)
	SLC4A1	Anion exchange protein. (924 aa)
	HSPA9	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
	M3YA03_MUSPF	Uncharacterized protein. (666 aa)
	C15orf41	Chromosome 15 open reading frame 41. (281 aa)
	LYAR	Ly1 antibody reactive. (387 aa)
	TRIM10	Tripartite motif containing 10. (486 aa)
	ADAR	Adenosine deaminase RNA specific. (1166 aa)
	ETV2	ETS variant 2. (344 aa)
	ARID4A	AT-rich interaction domain 4A. (1257 aa)
	KIT	KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (948 aa)
	ERCC2	ERCC excision repair 2, TFIIH core complex helicase subunit. (815 aa)
	NCKAP1L	NCK associated protein 1 like. (1134 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (590 aa)
	JAK2	Tyrosine-protein kinase. (1130 aa)
	HCLS1	Hematopoietic cell-specific Lyn substrate 1. (474 aa)
	ZBTB7A	Zinc finger and BTB domain containing 7A. (550 aa)
	DNASE2	Deoxyribonuclease 2, lysosomal. (393 aa)
	KLF1	Kruppel like factor 1. (381 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (388 aa)
	DMTN	Dematin actin binding protein. (350 aa)
	BCL6	BCL6 transcription repressor. (706 aa)
	ALAS2	5-aminolevulinate synthase. (586 aa)
	RCOR1	REST corepressor 1. (376 aa)
	SLC25A38	Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (304 aa)
	M3XSY8_MUSPF	Uncharacterized protein. (300 aa)
	M3XSY7_MUSPF	Uncharacterized protein. (242 aa)
	UFL1	UFM1 specific ligase 1. (792 aa)
	RB1	RB transcriptional corepressor 1. (948 aa)
	TMEM14C	Transmembrane protein 14C. (114 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB10	SLC25A38	ENSMPUP00000012308	ENSMPUP00000002446	ATP binding cassette subfamily B member 10.	Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.	0.431
ABCB10	TMEM14C	ENSMPUP00000012308	ENSMPUP00000000607	ATP binding cassette subfamily B member 10.	Transmembrane protein 14C.	0.531
ADD1	DMTN	ENSMPUP00000010846	ENSMPUP00000003961	Adducin 1.	Dematin actin binding protein.	0.735
ADD1	SLC4A1	ENSMPUP00000010846	ENSMPUP00000009368	Adducin 1.	Anion exchange protein.	0.495
AHSP	ALAS2	ENSMPUP00000011240	ENSMPUP00000003270	Alpha hemoglobin stabilizing protein.	5-aminolevulinate synthase.	0.611
AHSP	EPB42	ENSMPUP00000011240	ENSMPUP00000010000	Alpha hemoglobin stabilizing protein.	Erythrocyte membrane protein band 4.2.	0.953
AHSP	FLVCR1	ENSMPUP00000011240	ENSMPUP00000013313	Alpha hemoglobin stabilizing protein.	Feline leukemia virus subgroup C cellular receptor 1.	0.441
AHSP	GATA1	ENSMPUP00000011240	ENSMPUP00000013553	Alpha hemoglobin stabilizing protein.	GATA binding protein 1.	0.545
AHSP	KLF1	ENSMPUP00000011240	ENSMPUP00000004508	Alpha hemoglobin stabilizing protein.	Kruppel like factor 1.	0.420
AHSP	SLC4A1	ENSMPUP00000011240	ENSMPUP00000009368	Alpha hemoglobin stabilizing protein.	Anion exchange protein.	0.778
ALAS2	AHSP	ENSMPUP00000003270	ENSMPUP00000011240	5-aminolevulinate synthase.	Alpha hemoglobin stabilizing protein.	0.611
ALAS2	EPB42	ENSMPUP00000003270	ENSMPUP00000010000	5-aminolevulinate synthase.	Erythrocyte membrane protein band 4.2.	0.622
ALAS2	GATA1	ENSMPUP00000003270	ENSMPUP00000013553	5-aminolevulinate synthase.	GATA binding protein 1.	0.610
ALAS2	KLF1	ENSMPUP00000003270	ENSMPUP00000004508	5-aminolevulinate synthase.	Kruppel like factor 1.	0.552
ALAS2	SLC25A38	ENSMPUP00000003270	ENSMPUP00000002446	5-aminolevulinate synthase.	Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.	0.637
ALAS2	SLC4A1	ENSMPUP00000003270	ENSMPUP00000009368	5-aminolevulinate synthase.	Anion exchange protein.	0.623
ARID4A	KMT2E	ENSMPUP00000006085	ENSMPUP00000018147	AT-rich interaction domain 4A.	Lysine methyltransferase 2E.	0.439
ARID4A	RB1	ENSMPUP00000006085	ENSMPUP00000001411	AT-rich interaction domain 4A.	RB transcriptional corepressor 1.	0.871
ARID4A	RCOR1	ENSMPUP00000006085	ENSMPUP00000002613	AT-rich interaction domain 4A.	REST corepressor 1.	0.612
BCL6	GATA3	ENSMPUP00000003385	ENSMPUP00000016298	BCL6 transcription repressor.	GATA binding protein 3.	0.568