(62 nodes) Neutrophil chemotaxis network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SLC37A4	Solute carrier family 37 member 4. (429 aa)
	CCL21	SCY domain-containing protein. (137 aa)
	CCL19	C-C motif chemokine. (108 aa)
	JAML	Junction adhesion molecule like. (422 aa)
	CCL17	C-C motif chemokine. (99 aa)
	CX3CL1	C-X3-C motif chemokine ligand 1. (461 aa)
	CCL22	C-C motif chemokine. (93 aa)
	M3XTP4_MUSPF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
	M3XTF4_MUSPF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (147 aa)
	CCL20	C-C motif chemokine. (97 aa)
	PDE4B	Phosphodiesterase. (544 aa)
	M3XNV5_MUSPF	PDE4_UCR domain-containing protein. (232 aa)
	M3XNV3_MUSPF	Uncharacterized protein. (93 aa)
	PPIB	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
	PIKFYVE	Phosphoinositide kinase, FYVE-type zinc finger containing. (2099 aa)
	M3XN61_MUSPF	SCY domain-containing protein. (112 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (847 aa)
	M3Y2R7_MUSPF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (163 aa)
	M3Y2X7_MUSPF	Galectin. (287 aa)
	M3Y653_MUSPF	Protein kinase domain-containing protein. (212 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (845 aa)
	DPEP1	Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (410 aa)
	M3Y995_MUSPF	SCY domain-containing protein. (148 aa)
	M3Y9X7_MUSPF	PPIase cyclophilin-type domain-containing protein. (120 aa)
	S100A8	Protein S100; Belongs to the S-100 family. (89 aa)
	M3YAG4_MUSPF	EF-hand domain-containing protein; Belongs to the S-100 family. (189 aa)
	CXCL11	C-X-C motif chemokine. (132 aa)
	CXCL10	C-X-C motif chemokine. (98 aa)
	M3YCN5_MUSPF	C-X-C motif chemokine. (83 aa)
	M3YCR4_MUSPF	C-X-C motif chemokine. (108 aa)
	PPBP	C-X-C motif chemokine. (118 aa)
	CXCL8	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
	CXADR	Uncharacterized protein. (386 aa)
	M3YPC0_MUSPF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (131 aa)
	TREM1	Ig-like domain-containing protein. (234 aa)
	EDN2	Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family. (178 aa)
	M3YRX8_MUSPF	Ig-like domain-containing protein. (243 aa)
	FCER1G	Fc fragment of IgE receptor Ig. (86 aa)
	ITGA1	Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
	M3YT26_MUSPF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (164 aa)
	CSF3R	Colony stimulating factor 3 receptor. (839 aa)
	CCL8	C-C motif chemokine ligand 8. (99 aa)
	CCL13	C-C motif chemokine. (98 aa)
	M3YU58_MUSPF	SCY domain-containing protein. (138 aa)
	M3YU59_MUSPF	SCY domain-containing protein. (123 aa)
	M3YU63_MUSPF	C-C motif chemokine. (107 aa)
	M3YU65_MUSPF	C-C motif chemokine. (93 aa)
	M3YU74_MUSPF	C-C motif chemokine. (92 aa)
	NCKAP1L	NCK associated protein 1 like. (1134 aa)
	M3Z7C5_MUSPF	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (356 aa)
	CCL24	C-C motif chemokine ligand 24. (119 aa)
	M3Z880_MUSPF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (164 aa)
	CXCL13	C-X-C motif chemokine. (109 aa)
	SRP54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
	M3YYJ8_MUSPF	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (339 aa)
	PREX1	Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1648 aa)
	M3Z3B6_MUSPF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (159 aa)
	M3Z4Z6_MUSPF	Galectin. (248 aa)
	M3Z660_MUSPF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (155 aa)
	C5AR1	Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
	M3Y1Z4_MUSPF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (156 aa)
	CKLF	Chemokine like factor. (117 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCL13	CCL17	ENSMPUP00000014735	ENSMPUP00000004366	C-C motif chemokine.	C-C motif chemokine.	0.461
CCL13	CCL20	ENSMPUP00000014735	ENSMPUP00000001364	C-C motif chemokine.	C-C motif chemokine.	0.447
CCL13	CCL21	ENSMPUP00000014735	ENSMPUP00000004488	C-C motif chemokine.	SCY domain-containing protein.	0.936
CCL13	CCL22	ENSMPUP00000014735	ENSMPUP00000004347	C-C motif chemokine.	C-C motif chemokine.	0.658
CCL13	CCL24	ENSMPUP00000014735	ENSMPUP00000015926	C-C motif chemokine.	C-C motif chemokine ligand 24.	0.995
CCL13	CCL8	ENSMPUP00000014735	ENSMPUP00000014734	C-C motif chemokine.	C-C motif chemokine ligand 8.	0.990
CCL13	CXCL10	ENSMPUP00000014735	ENSMPUP00000008619	C-C motif chemokine.	C-X-C motif chemokine.	0.948
CCL13	CXCL11	ENSMPUP00000014735	ENSMPUP00000008613	C-C motif chemokine.	C-X-C motif chemokine.	0.939
CCL13	M3XN61_MUSPF	ENSMPUP00000014735	ENSMPUP00000000511	C-C motif chemokine.	SCY domain-containing protein.	0.859
CCL13	M3Y995_MUSPF	ENSMPUP00000014735	ENSMPUP00000007902	C-C motif chemokine.	SCY domain-containing protein.	0.488
CCL13	M3YCN5_MUSPF	ENSMPUP00000014735	ENSMPUP00000009092	C-C motif chemokine.	C-X-C motif chemokine.	0.813
CCL13	M3YCR4_MUSPF	ENSMPUP00000014735	ENSMPUP00000009121	C-C motif chemokine.	C-X-C motif chemokine.	0.856
CCL13	M3YU59_MUSPF	ENSMPUP00000014735	ENSMPUP00000014869	C-C motif chemokine.	SCY domain-containing protein.	0.939
CCL13	M3YU65_MUSPF	ENSMPUP00000014735	ENSMPUP00000014875	C-C motif chemokine.	C-C motif chemokine.	0.493
CCL13	M3YU74_MUSPF	ENSMPUP00000014735	ENSMPUP00000014884	C-C motif chemokine.	C-C motif chemokine.	0.536
CCL13	M3YYJ8_MUSPF	ENSMPUP00000014735	ENSMPUP00000016408	C-C motif chemokine.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.497
CCL13	M3Z7C5_MUSPF	ENSMPUP00000014735	ENSMPUP00000019488	C-C motif chemokine.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.863
CCL13	PPBP	ENSMPUP00000014735	ENSMPUP00000009133	C-C motif chemokine.	C-X-C motif chemokine.	0.933
CCL17	CCL13	ENSMPUP00000004366	ENSMPUP00000014735	C-C motif chemokine.	C-C motif chemokine.	0.461
CCL17	CCL19	ENSMPUP00000004366	ENSMPUP00000004471	C-C motif chemokine.	C-C motif chemokine.	0.572