STRINGSTRING
ATF3 ATF3 PARP16 PARP16 DERL1 DERL1 SERP2 SERP2 DDIT3 DDIT3 OS9 OS9 DNAJC10 DNAJC10 DERL3 DERL3 AMFR AMFR ATF6 ATF6 CREB3L2 CREB3L2 HERPUD1 HERPUD1 CREB3L3 CREB3L3 CREB3 CREB3 CREB3L1 CREB3L1 VAPB VAPB EIF2S1 EIF2S1 WFS1 WFS1 HERPUD2 HERPUD2 CREB3L4 CREB3L4 EIF2AK3 EIF2AK3 M3YEN4_MUSPF M3YEN4_MUSPF YOD1 YOD1 EIF2AK2 EIF2AK2 ATF6B ATF6B ERLEC1 ERLEC1 SELENOS SELENOS BHLHA15 BHLHA15 PTPN1 PTPN1 EP300 EP300 TBL2 TBL2 RHBDD2 RHBDD2 CDK5RAP3 CDK5RAP3 ERN1 ERN1 QRICH1 QRICH1 M3YRV1_MUSPF M3YRV1_MUSPF HSPA5 HSPA5 M3YQ14_MUSPF M3YQ14_MUSPF M3YPM9_MUSPF M3YPM9_MUSPF ERN2 ERN2 TMTC4 TMTC4 DERL2 DERL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATF3Activating transcription factor 3. (181 aa)
PARP16Poly [ADP-ribose] polymerase. (322 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (252 aa)
SERP2Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (71 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
OS9OS9 endoplasmic reticulum lectin. (672 aa)
DNAJC10DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. (794 aa)
DERL3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (231 aa)
AMFRAutocrine motility factor receptor. (548 aa)
ATF6Activating transcription factor 6. (659 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (409 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (473 aa)
CREB3cAMP responsive element binding protein 3. (353 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
VAPBVAMP associated protein B and C. (243 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
WFS1Wolframin ER transmembrane glycoprotein. (888 aa)
HERPUD2HERPUD family member 2. (406 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (386 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1065 aa)
M3YEN4_MUSPFBZIP domain-containing protein. (358 aa)
YOD1YOD1 deubiquitinase. (348 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (518 aa)
ATF6BActivating transcription factor 6 beta. (707 aa)
ERLEC1Endoplasmic reticulum lectin 1. (499 aa)
SELENOSSelenoprotein S. (188 aa)
BHLHA15Basic helix-loop-helix family member a15. (187 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (424 aa)
EP300E1A binding protein p300. (2425 aa)
TBL2Transducin beta like 2. (367 aa)
RHBDD2Rhomboid domain containing 2. (387 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (504 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (975 aa)
QRICH1Glutamine rich 1. (779 aa)
M3YRV1_MUSPFUncharacterized protein. (286 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
M3YQ14_MUSPFBZIP domain-containing protein. (346 aa)
M3YPM9_MUSPFBZIP domain-containing protein. (351 aa)
ERN2Endoplasmic reticulum to nucleus signaling 2. (926 aa)
TMTC4Transmembrane O-mannosyltransferase targeting cadherins 4. (741 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (230 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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