STRINGSTRING
PARK7 PARK7 M3Z8V0_MUSPF M3Z8V0_MUSPF M3Z8P6_MUSPF M3Z8P6_MUSPF TOB1 TOB1 TENT5D TENT5D BAG5 BAG5 TRIM60 TRIM60 M3Z4Z5_MUSPF M3Z4Z5_MUSPF TENT5A TENT5A E2F1 E2F1 SIRT2 SIRT2 ZFP36 ZFP36 CTSA CTSA APOBEC1 APOBEC1 PML PML TIMP4 TIMP4 RYBP RYBP A1CF A1CF SUFU SUFU FOXK1 FOXK1 BCL2 BCL2 TARDBP TARDBP MTOR MTOR TSPO TSPO NOCT NOCT DKC1 DKC1 PINK1 PINK1 M3YXD0_MUSPF M3YXD0_MUSPF TRAF5 TRAF5 HNRNPU HNRNPU TENT5B TENT5B ZCCHC17 ZCCHC17 IGF2BP1 IGF2BP1 TMEM39B TMEM39B M3YUZ9_MUSPF M3YUZ9_MUSPF M3YUY2_MUSPF M3YUY2_MUSPF TLK2 TLK2 PABPC1 PABPC1 WAC WAC SMARCC1 SMARCC1 C16orf96 C16orf96 GDNF GDNF THRAP3 THRAP3 HNRNPD HNRNPD WNT1 WNT1 USP7 USP7 AXIN2 AXIN2 CLEC16A CLEC16A PARN PARN POLDIP2 POLDIP2 CPTP CPTP WDR6 WDR6 MFSD2A MFSD2A SVIP SVIP YBX1 YBX1 UBXN1 UBXN1 TREML1 TREML1 KDM4A KDM4A TREM2 TREM2 NBAS NBAS LARP1 LARP1 IGF2BP3 IGF2BP3 ANGEL2 ANGEL2 SMG1 SMG1 TIMP1 TIMP1 RBM10 RBM10 PHAX PHAX EIF4ENIF1 EIF4ENIF1 USP9X USP9X TIMP2 TIMP2 HMOX1 HMOX1 TIMP3 TIMP3 PDCL3 PDCL3 IKBKE IKBKE TRIM39 TRIM39 KLHL40 KLHL40 M3YK49_MUSPF M3YK49_MUSPF ATP2B4 ATP2B4 MTM1 MTM1 DHX9 DHX9 TRDMT1 TRDMT1 FMR1 FMR1 M3YJ27_MUSPF M3YJ27_MUSPF QSOX1 QSOX1 BAG6 BAG6 TRAF2 TRAF2 M3YHM7_MUSPF M3YHM7_MUSPF GIPC2 GIPC2 EHMT2 EHMT2 PKP1 PKP1 VIP VIP STAT3 STAT3 PHF23 PHF23 TBC1D14 TBC1D14 M3YFM7_MUSPF M3YFM7_MUSPF BECN1 BECN1 FEZ2 FEZ2 CAMLG CAMLG MAPKAPK2 MAPKAPK2 IL10 IL10 M3YEL8_MUSPF M3YEL8_MUSPF TIGAR TIGAR M3YCY6_MUSPF M3YCY6_MUSPF MEIOC MEIOC TP53 TP53 DDRGK1 DDRGK1 HFE HFE PKP3 PKP3 M3YAS3_MUSPF M3YAS3_MUSPF TMEM39A TMEM39A BMF BMF NRDE2 NRDE2 NRBP2 NRBP2 ELAVL1 ELAVL1 BOLL BOLL M3Y8S0_MUSPF M3Y8S0_MUSPF NSUN2 NSUN2 PTPN3 PTPN3 DFFB DFFB ELAVL4 ELAVL4 SGTA SGTA LEP LEP RBM38 RBM38 FEZ1 FEZ1 CHMP4A CHMP4A SORL1 SORL1 CSDE1 CSDE1 RBM46 RBM46 INS INS USP14 USP14 SCFD1 SCFD1 SYNCRIP SYNCRIP LRIG2 LRIG2 PLIN5 PLIN5 OGT OGT TENT2 TENT2 DHX34 DHX34 UBQLN4 UBQLN4 GPLD1 GPLD1 CSNK2A2 CSNK2A2 HTR2B HTR2B TTC36 TTC36 UCHL5 UCHL5 NOP53 NOP53 IL10RA IL10RA LZTS1 LZTS1 RUBCN RUBCN M3XY50_MUSPF M3XY50_MUSPF GIPC3 GIPC3 HIPK2 HIPK2 KLHL22 KLHL22 RASIP1 RASIP1 CCAR2 CCAR2 IGF2BP2 IGF2BP2 N4BP1 N4BP1 GIPC1 GIPC1 MYD88 MYD88 DHX36 DHX36 TRIM75P TRIM75P LOC101688276 LOC101688276 MTMR9 MTMR9 TENT5C TENT5C DAZL DAZL SEC22B SEC22B RNF41 RNF41 EIF3H EIF3H PBK PBK HNRNPAB HNRNPAB LEPR LEPR DAPL1 DAPL1 LRRK2 LRRK2 ETFBKMT ETFBKMT SMCR8 SMCR8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PARK7Parkinsonism associated deglycase. (189 aa)
M3Z8V0_MUSPFUncharacterized protein; Belongs to the universal ribosomal protein uL5 family. (178 aa)
M3Z8P6_MUSPFUncharacterized protein; Belongs to the universal ribosomal protein uL5 family. (178 aa)
TOB1Transducer of ERBB2, 1. (345 aa)
TENT5DTerminal nucleotidyltransferase 5D. (387 aa)
BAG5BCL2 associated athanogene 5. (447 aa)
TRIM60Tripartite motif containing 60. (466 aa)
M3Z4Z5_MUSPFUncharacterized protein. (472 aa)
TENT5ATerminal nucleotidyltransferase 5A. (446 aa)
E2F1E2F transcription factor 1. (354 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (412 aa)
ZFP36ZFP36 ring finger protein. (327 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (495 aa)
APOBEC1Apolipoprotein B mRNA editing protein. (236 aa)
PMLPromyelocytic leukemia. (876 aa)
TIMP4TIMP metallopeptidase inhibitor 4. (224 aa)
RYBPRING1 and YY1 binding protein. (219 aa)
A1CFAPOBEC1 complementation factor. (592 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (484 aa)
FOXK1Forkhead box K1. (614 aa)
BCL2BCL2 apoptosis regulator. (207 aa)
TARDBPTAR DNA binding protein. (298 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2552 aa)
TSPOTranslocator protein. (169 aa)
NOCTNocturnin. (365 aa)
DKC1Dyskerin pseudouridine synthase 1. (539 aa)
PINK1PTEN induced kinase 1. (580 aa)
M3YXD0_MUSPFFork-head domain-containing protein. (575 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (592 aa)
TENT5BTerminal nucleotidyltransferase 5B. (427 aa)
ZCCHC17Zinc finger CCHC-type containing 17. (240 aa)
IGF2BP1Insulin like growth factor 2 mRNA binding protein 1. (506 aa)
TMEM39BTransmembrane protein 39B. (492 aa)
M3YUZ9_MUSPFMyotubularin phosphatase domain-containing protein. (540 aa)
M3YUY2_MUSPFUncharacterized protein. (181 aa)
TLK2Tousled like kinase 2. (750 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (571 aa)
WACWW domain containing adaptor with coiled-coil. (601 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1006 aa)
C16orf96Chromosome 16 open reading frame 96. (1107 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
THRAP3Thyroid hormone receptor associated protein 3. (957 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (277 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1055 aa)
AXIN2Axin 2. (842 aa)
CLEC16AC-type lectin domain containing 16A. (1048 aa)
PARNPoly(A)-specific ribonuclease. (638 aa)
POLDIP2DNA polymerase delta interacting protein 2. (368 aa)
CPTPGlycolipid transfer protein domain containing 1. (214 aa)
WDR6WD repeat domain 6. (1120 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (529 aa)
SVIPSmall VCP interacting protein. (96 aa)
YBX1Y-box binding protein 1. (330 aa)
UBXN1UBX domain protein 1. (296 aa)
TREML1Triggering receptor expressed on myeloid cells like 1. (314 aa)
KDM4AUncharacterized protein. (1066 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
NBASNeuroblastoma amplified sequence. (2371 aa)
LARP1La ribonucleoprotein domain family member 1. (907 aa)
IGF2BP3Insulin like growth factor 2 mRNA binding protein 3. (579 aa)
ANGEL2Angel homolog 2. (544 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3658 aa)
TIMP1TIMP metallopeptidase inhibitor 1. (207 aa)
RBM10RNA binding motif protein 10. (1060 aa)
PHAXPhosphorylated adaptor for RNA export. (394 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E nuclear import factor 1. (1024 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2554 aa)
TIMP2TIMP metallopeptidase inhibitor 2. (183 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
TIMP3TIMP metallopeptidase inhibitor 3. (211 aa)
PDCL3Phosducin like 3. (240 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (719 aa)
TRIM39Tripartite motif containing 39. (488 aa)
KLHL40Kelch like family member 40. (624 aa)
M3YK49_MUSPFPPR_long domain-containing protein. (1397 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1206 aa)
MTM1Myotubularin 1. (603 aa)
DHX9DExH-box helicase 9. (1200 aa)
TRDMT1tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (391 aa)
FMR1Fragile X mental retardation 1. (615 aa)
M3YJ27_MUSPFUncharacterized protein. (524 aa)
QSOX1Sulfhydryl oxidase. (621 aa)
BAG6BCL2 associated athanogene 6. (1129 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
M3YHM7_MUSPFFork-head domain-containing protein. (528 aa)
GIPC2GIPC PDZ domain containing family member 2. (312 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1270 aa)
PKP1Plakophilin 1. (696 aa)
VIPVasoactive intestinal peptide. (170 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
PHF23PHD finger protein 23. (403 aa)
TBC1D14TBC1 domain family member 14. (693 aa)
M3YFM7_MUSPFSEFIR domain-containing protein. (557 aa)
BECN1Beclin 1. (448 aa)
FEZ2Fasciculation and elongation protein zeta 2. (376 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (296 aa)
MAPKAPK2MAPK activated protein kinase 2. (319 aa)
IL10Interleukin 10. (220 aa)
M3YEL8_MUSPFUncharacterized protein. (172 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
M3YCY6_MUSPFSEFIR domain-containing protein. (532 aa)
MEIOCMeiosis specific with coiled-coil domain. (960 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
DDRGK1DDRGK domain containing 1. (315 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (403 aa)
PKP3Plakophilin 3. (810 aa)
M3YAS3_MUSPFRibosomal_L7Ae domain-containing protein. (541 aa)
TMEM39ATransmembrane protein 39A. (488 aa)
BMFBcl2 modifying factor. (184 aa)
NRDE2NRDE-2, necessary for RNA interference, domain containing. (1152 aa)
NRBP2Nuclear receptor binding protein 2. (492 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (326 aa)
BOLLBoule homolog, RNA binding protein. (294 aa)
M3Y8S0_MUSPFRRM domain-containing protein. (534 aa)
NSUN2NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (720 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (994 aa)
DFFBDNA fragmentation factor subunit beta. (301 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (380 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (313 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa)
RBM38RNA binding motif protein 38. (202 aa)
FEZ1Fasciculation and elongation protein zeta 1. (446 aa)
CHMP4ACharged multivesicular body protein 4A. (266 aa)
SORL1Sortilin related receptor 1. (2211 aa)
CSDE1Cold shock domain containing E1. (784 aa)
RBM46RNA binding motif protein 46. (485 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (109 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (494 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (642 aa)
SYNCRIPSynaptotagmin binding cytoplasmic RNA interacting protein. (562 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1065 aa)
PLIN5Perilipin; Belongs to the perilipin family. (480 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1047 aa)
TENT2Terminal nucleotidyltransferase 2. (483 aa)
DHX34DExH-box helicase 34. (1075 aa)
UBQLN4Ubiquilin 4. (591 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (875 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (326 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
TTC36Tetratricopeptide repeat domain 36. (188 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (329 aa)
NOP53NOP53 ribosome biogenesis factor. (486 aa)
IL10RAInterleukin 10 receptor subunit alpha. (611 aa)
LZTS1Leucine zipper tumor suppressor 1. (606 aa)
RUBCNRubicon autophagy regulator. (1019 aa)
M3XY50_MUSPFUncharacterized protein. (459 aa)
GIPC3GIPC PDZ domain containing family member 3. (252 aa)
HIPK2Homeodomain interacting protein kinase 2. (1165 aa)
KLHL22Kelch like family member 22. (634 aa)
RASIP1Ras interacting protein 1. (966 aa)
CCAR2Cell cycle and apoptosis regulator 2. (925 aa)
IGF2BP2Insulin like growth factor 2 mRNA binding protein 2. (501 aa)
N4BP1NEDD4 binding protein 1. (810 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
DHX36DEAH-box helicase 36. (1013 aa)
TRIM75PTripartite motif containing 75, pseudogene. (485 aa)
LOC101688276Uncharacterized protein. (479 aa)
MTMR9Myotubularin related protein 9. (573 aa)
TENT5CTerminal nucleotidyltransferase 5C. (409 aa)
DAZLDeleted in azoospermia like. (297 aa)
SEC22BSEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa)
RNF41Ring finger protein 41. (317 aa)
EIF3HEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (352 aa)
PBKPDZ binding kinase. (323 aa)
HNRNPABHeterogeneous nuclear ribonucleoprotein A/B. (341 aa)
LEPRLeptin receptor. (1164 aa)
DAPL1Death associated protein like 1. (107 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
ETFBKMTElectron transfer flavoprotein subunit beta lysine methyltransferase. (266 aa)
SMCR8SMCR8-C9orf72 complex subunit. (937 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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