36 items (Mustela putorius) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	SUPT16H	SPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
	SSRP1	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa)
	RNF168	E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (572 aa)
	SIRT6	Sirtuin 6. (359 aa)
	NAP1L4	Nucleosome assembly protein 1 like 4; Belongs to the nucleosome assembly protein (NAP) family. (386 aa)
	ACTR10	Actin related protein 10; Belongs to the actin family. (419 aa)
	PWWP3A	PWWP domain containing 3A, DNA repair factor. (678 aa)
	HMGN1	High mobility group nucleosome binding domain 1. (133 aa)
	HMGN4	High mobility group nucleosomal binding domain 4. (90 aa)
	RNF169	Ring finger protein 169. (607 aa)
	M3YD94_MUSPF	SLIDE domain-containing protein. (67 aa)
	M3YD97_MUSPF	HAND domain-containing protein. (88 aa)
	M3YDA0_MUSPF	Helicase C-terminal domain-containing protein. (105 aa)
	M3YDA5_MUSPF	Helicase ATP-binding domain-containing protein. (91 aa)
	MACROH2A1	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
	MLLT10	MLLT10 histone lysine methyltransferase DOT1L cofactor. (1007 aa)
	SAP30L	SAP30 like. (182 aa)
	GALK1	Galactokinase 1. (392 aa)
	NOC2L	NOC2 like nucleolar associated transcriptional repressor. (760 aa)
	SUPT6H	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
	GLYR1	Glyoxylate reductase 1 homolog. (553 aa)
	MLLT6	MLLT6, PHD finger containing. (1090 aa)
	RCC1	Regulator of chromosome condensation 1. (451 aa)
	ZNHIT1	Zinc finger HIT-type containing 1. (156 aa)
	HP1BP3	Heterochromatin protein 1 binding protein 3. (553 aa)
	M3Z0L7_MUSPF	Uncharacterized protein. (125 aa)
	SMARCA1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1132 aa)
	M3Z1E7_MUSPF	Uncharacterized protein. (109 aa)
	DNTTIP1	Deoxynucleotidyltransferase terminal interacting protein 1. (329 aa)
	HMGN3	High mobility group nucleosomal binding domain 3. (180 aa)
	PARP2	Poly [ADP-ribose] polymerase. (567 aa)
	H1-6	Histone cluster 1 H1 family member t. (212 aa)
	M3Z4T2_MUSPF	Uncharacterized protein. (90 aa)
	PWWP3B	PWWP domain containing 3B. (696 aa)
	M3Z5K2_MUSPF	Uncharacterized protein. (673 aa)
	M3Z877_MUSPF	Uncharacterized protein. (89 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GLYR1	MACROH2A1	ENSMPUP00000014774	ENSMPUP00000009936	Glyoxylate reductase 1 homolog.	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.	0.833
H1-6	HP1BP3	ENSMPUP00000018498	ENSMPUP00000015985	Histone cluster 1 H1 family member t.	Heterochromatin protein 1 binding protein 3.	0.439
H1-6	M3Z0L7_MUSPF	ENSMPUP00000018498	ENSMPUP00000017129	Histone cluster 1 H1 family member t.	Uncharacterized protein.	0.777
H1-6	NAP1L4	ENSMPUP00000018498	ENSMPUP00000005035	Histone cluster 1 H1 family member t.	Nucleosome assembly protein 1 like 4; Belongs to the nucleosome assembly protein (NAP) family.	0.526
HMGN1	HMGN3	ENSMPUP00000008485	ENSMPUP00000017980	High mobility group nucleosome binding domain 1.	High mobility group nucleosomal binding domain 3.	0.408
HMGN1	HMGN4	ENSMPUP00000008485	ENSMPUP00000008544	High mobility group nucleosome binding domain 1.	High mobility group nucleosomal binding domain 4.	0.424
HMGN3	HMGN1	ENSMPUP00000017980	ENSMPUP00000008485	High mobility group nucleosomal binding domain 3.	High mobility group nucleosome binding domain 1.	0.408
HMGN4	HMGN1	ENSMPUP00000008544	ENSMPUP00000008485	High mobility group nucleosomal binding domain 4.	High mobility group nucleosome binding domain 1.	0.424
HP1BP3	H1-6	ENSMPUP00000015985	ENSMPUP00000018498	Heterochromatin protein 1 binding protein 3.	Histone cluster 1 H1 family member t.	0.439
M3YD94_MUSPF	MACROH2A1	ENSMPUP00000009301	ENSMPUP00000009936	SLIDE domain-containing protein.	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.	0.489
M3YD94_MUSPF	SUPT16H	ENSMPUP00000009301	ENSMPUP00000000170	SLIDE domain-containing protein.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.433
M3YD97_MUSPF	M3YDA0_MUSPF	ENSMPUP00000009304	ENSMPUP00000009307	HAND domain-containing protein.	Helicase C-terminal domain-containing protein.	0.900
M3YD97_MUSPF	M3YDA5_MUSPF	ENSMPUP00000009304	ENSMPUP00000009312	HAND domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.900
M3YD97_MUSPF	MACROH2A1	ENSMPUP00000009304	ENSMPUP00000009936	HAND domain-containing protein.	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.	0.489
M3YD97_MUSPF	SUPT16H	ENSMPUP00000009304	ENSMPUP00000000170	HAND domain-containing protein.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.433
M3YDA0_MUSPF	M3YD97_MUSPF	ENSMPUP00000009307	ENSMPUP00000009304	Helicase C-terminal domain-containing protein.	HAND domain-containing protein.	0.900
M3YDA0_MUSPF	M3YDA5_MUSPF	ENSMPUP00000009307	ENSMPUP00000009312	Helicase C-terminal domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.951
M3YDA0_MUSPF	MACROH2A1	ENSMPUP00000009307	ENSMPUP00000009936	Helicase C-terminal domain-containing protein.	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.	0.489
M3YDA0_MUSPF	SUPT16H	ENSMPUP00000009307	ENSMPUP00000000170	Helicase C-terminal domain-containing protein.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.433
M3YDA5_MUSPF	M3YD97_MUSPF	ENSMPUP00000009312	ENSMPUP00000009304	Helicase ATP-binding domain-containing protein.	HAND domain-containing protein.	0.900