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| | KPTN | Kaptin, actin binding protein. (436 aa) |
| | LAMTOR2 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa) |
| | GPR137C | G protein-coupled receptor 137C. (421 aa) |
| | SMCR8 | SMCR8-C9orf72 complex subunit. (937 aa) |
| | TBC1D7 | TBC1 domain family member 7. (270 aa) |
| | DEPTOR | DEP domain containing MTOR interacting protein. (279 aa) |
| | MIOS | Meiosis regulator for oocyte development. (877 aa) |
| | MAPKAPK5 | MAPK activated protein kinase 5. (473 aa) |
| | AKT1S1 | AKT1 substrate 1. (285 aa) |
| | SH3BP4 | SH3 domain binding protein 4. (962 aa) |
| | PIH1D1 | PIH1 domain containing 1. (290 aa) |
| | RRAGB | Ras related GTP binding B. (336 aa) |
| | KLHL22 | Kelch like family member 22. (634 aa) |
| | LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (92 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (230 aa) |
| | SEH1L | SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (421 aa) |
| | FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (579 aa) |
| | TNFAIP8L1 | TNF alpha induced protein 8 like 1. (200 aa) |
| | RRAGA | Ras related GTP binding A. (313 aa) |
| | RELN | Reelin. (3458 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (277 aa) |
| | GNA12 | G protein subunit alpha 12. (305 aa) |
| | TTI1 | TELO2 interacting protein 1. (1084 aa) |
| | FAM83D | Family with sequence similarity 83 member D. (621 aa) |
| | SEC13 | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (322 aa) |
| | C12orf66 | Chromosome 12 open reading frame 66. (445 aa) |
| | TMEM130 | Transmembrane protein 130. (423 aa) |
| | M3YXL8_MUSPF | Uncharacterized protein. (349 aa) |
| | NPRL3 | NPR3 like, GATOR1 complex subunit. (569 aa) |
| | WDR24 | WD repeat domain 24. (790 aa) |
| | C9orf72 | C9orf72-SMCR8 complex subunit. (481 aa) |
| | LAMTOR4 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (98 aa) |
| | TELO2 | Telomere maintenance 2. (827 aa) |
| | SESN2 | Sestrin 2. (479 aa) |
| | TSC2 | TSC complex subunit 2. (1906 aa) |
| | MINAR1 | Membrane integral NOTCH2 associated receptor 1. (918 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (328 aa) |
| | GOLPH3 | Golgi phosphoprotein 3. (236 aa) |
| | WAC | WW domain containing adaptor with coiled-coil. (601 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1732 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (517 aa) |
| | GPAT3 | Glycerol-3-phosphate acyltransferase 3. (433 aa) |
| | CLEC16A | C-type lectin domain containing 16A. (1048 aa) |
| | RRAGC | Ras related GTP binding C. (399 aa) |
| | ROS1 | Tyrosine-protein kinase receptor. (2342 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | OTUD5 | OTU deubiquitinase 5. (566 aa) |
| | TREML1 | Triggering receptor expressed on myeloid cells like 1. (314 aa) |
| | SZT2 | SZT2 subunit of KICSTOR complex. (3426 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (230 aa) |
| | ARAF | V-raf murine sarcoma 3611 viral oncoprotein-like protein. (606 aa) |
| | UBR2 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1755 aa) |
| | CASTOR1 | Cytosolic arginine sensor for mTORC1 subunit 1. (329 aa) |
| | NPRL2 | NPR2 like, GATOR1 complex subunit. (380 aa) |
| | ENDOG | Endonuclease. (237 aa) |
| | GPR137 | G protein-coupled receptor 137. (485 aa) |
| | M3YMV5_MUSPF | DEP domain-containing protein. (1704 aa) |
| | USP9X | Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2554 aa) |
| | TSC1 | TSC complex subunit 1. (1165 aa) |
| | SESN3 | Sestrin 3. (495 aa) |
| | CTNS | Cystinosin, lysosomal cystine transporter. (388 aa) |
| | SIRT1 | Sirtuin 1. (557 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1244 aa) |
| | FNIP1 | Folliculin interacting protein 1. (797 aa) |
| | MTM1 | Myotubularin 1. (603 aa) |
| | DGKQ | Diacylglycerol kinase. (952 aa) |
| | LAMTOR1 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa) |
| | PDCD6 | Programmed cell death 6. (189 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (587 aa) |
| | UBR1 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1753 aa) |
| | WDR59 | WD repeat domain 59. (974 aa) |
| | SESN1 | Sestrin 1. (551 aa) |
| | LAMTOR3 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa) |
| | ITFG2 | Integrin alpha FG-GAP repeat containing 2. (444 aa) |
| | RRAGD | Ras related GTP binding D. (363 aa) |
| | GAS6 | Growth arrest specific 6. (541 aa) |
| | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4056 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (179 aa) |
| | TMEM127 | Transmembrane protein 127. (250 aa) |
| | TBCK | TBC1 domain containing kinase. (893 aa) |
| | FBXO9 | F-box protein 9. (432 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (443 aa) |
| | HDAC3 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (430 aa) |
| | LARS1 | Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1176 aa) |
| | BMT2 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (405 aa) |
| | SLC38A9 | Solute carrier family 38 member 9. (559 aa) |
| | M3Y830_MUSPF | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (417 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (824 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3057 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1134 aa) |
| | GBA | Glucosylceramidase. (547 aa) |
