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CLDN5 CLDN5 RALB RALB DERL1 DERL1 LRP1 LRP1 BLK BLK HIP1R HIP1R TCF7L2 TCF7L2 M3XSG3_MUSPF M3XSG3_MUSPF MARK3 MARK3 NMD3 NMD3 SPPL3 SPPL3 AKTIP AKTIP AMFR AMFR HIPK2 HIPK2 NVL NVL M3XZQ7_MUSPF M3XZQ7_MUSPF M3XZR5_MUSPF M3XZR5_MUSPF DTX3L DTX3L BMP4 BMP4 SPAG8 SPAG8 DACT1 DACT1 BMP2 BMP2 CAV1 CAV1 ADD2 ADD2 PLCL1 PLCL1 CDK5 CDK5 EPHB6 EPHB6 M3YAR0_MUSPF M3YAR0_MUSPF HFE HFE STING1 STING1 MAPRE3 MAPRE3 NPHP3 NPHP3 TRIM21 TRIM21 ARHGEF7 ARHGEF7 USP33 USP33 B2M B2M RIPK2 RIPK2 CAPRIN2 CAPRIN2 FLOT1 FLOT1 USP9X USP9X LRRK2 LRRK2 ABL1 ABL1 MFNG MFNG SPTA1 SPTA1 SPON1 SPON1 VTN VTN PIN1 PIN1 BAMBI BAMBI CTHRC1 CTHRC1 STK3 STK3 PKD1 PKD1 EP300 EP300 IDE IDE PLXND1 PLXND1 STK4 STK4 MAPRE1 MAPRE1 TRIB3 TRIB3 M3Z2L9_MUSPF M3Z2L9_MUSPF RAPGEF2 RAPGEF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
RALBRAS like proto-oncogene B. (206 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (252 aa)
LRP1LDL receptor related protein 1. (4544 aa)
BLKTyrosine-protein kinase. (500 aa)
HIP1RHuntingtin interacting protein 1 related. (884 aa)
TCF7L2Transcription factor 7 like 2. (514 aa)
M3XSG3_MUSPFCTNNB1_binding domain-containing protein. (169 aa)
MARK3Non-specific serine/threonine protein kinase. (737 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (504 aa)
SPPL3Signal peptide peptidase like 3. (347 aa)
AKTIPAKT interacting protein. (292 aa)
AMFRAutocrine motility factor receptor. (548 aa)
HIPK2Homeodomain interacting protein kinase 2. (1165 aa)
NVLNuclear VCP like. (854 aa)
M3XZQ7_MUSPFUbiquitin-like domain-containing protein. (311 aa)
M3XZR5_MUSPFRBR-type E3 ubiquitin transferase. (115 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (745 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
SPAG8Sperm associated antigen 8. (455 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (759 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
ADD2Adducin 2. (723 aa)
PLCL1Phosphoinositide phospholipase C. (1045 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
EPHB6EPH receptor B6. (1011 aa)
M3YAR0_MUSPFUncharacterized protein. (736 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (403 aa)
STING1Transmembrane protein 173. (378 aa)
MAPRE3Microtubule associated protein RP/EB family member 3. (294 aa)
NPHP3TPR_REGION domain-containing protein. (1331 aa)
TRIM21Tripartite motif containing 21. (468 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (844 aa)
USP33Ubiquitin specific peptidase 33; Belongs to the peptidase C19 family. (748 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (128 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
CAPRIN2Caprin family member 2. (1103 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (405 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2554 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (321 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2434 aa)
SPON1Spondin 1. (807 aa)
VTNSMB domain-containing protein. (470 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (162 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
CTHRC1Collagen triple helix repeat containing 1. (282 aa)
STK3Serine/threonine kinase 3. (418 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4230 aa)
EP300E1A binding protein p300. (2425 aa)
IDEInsulin degrading enzyme; Belongs to the peptidase M16 family. (1017 aa)
PLXND1Plexin D1. (1746 aa)
STK4Serine/threonine kinase 4. (487 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
TRIB3Tribbles pseudokinase 3. (358 aa)
M3Z2L9_MUSPFUncharacterized protein. (199 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1677 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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