STRINGSTRING
NAV3 NAV3 PRNP PRNP ZFP36 ZFP36 LAG3 LAG3 GATA3 GATA3 HOMER2 HOMER2 M3YVL3_MUSPF M3YVL3_MUSPF TBX21 TBX21 TNFAIP3 TNFAIP3 FOXP3 FOXP3 KAT5 KAT5 NR1H4 NR1H4 M3YGX4_MUSPF M3YGX4_MUSPF PTPRC PTPRC IL20RB IL20RB EZR EZR NOD2 NOD2 TRIM27 TRIM27 VSIG4 VSIG4 HDAC7 HDAC7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NAV3Neuron navigator 3. (2219 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (257 aa)
ZFP36ZFP36 ring finger protein. (327 aa)
LAG3Lymphocyte activating 3. (521 aa)
GATA3GATA binding protein 3. (444 aa)
HOMER2Homer scaffold protein 2. (386 aa)
M3YVL3_MUSPFWH1 domain-containing protein. (358 aa)
TBX21T-box transcription factor 21. (535 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
FOXP3Forkhead box P3. (433 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (472 aa)
M3YGX4_MUSPFUncharacterized protein. (369 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1298 aa)
IL20RBInterleukin 20 receptor subunit beta. (294 aa)
EZREzrin. (586 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1013 aa)
TRIM27Tripartite motif containing 27. (516 aa)
VSIG4V-set and immunoglobulin domain containing 4. (399 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (991 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: low (16%) [HD]