(17 nodes) Positive regulation of cell adhesion mediated by integrin network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NCKAP1L	NCK associated protein 1 like. (1134 aa)
	TGFB2	Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (414 aa)
	CD3E	CD3 epsilon antigen. (186 aa)
	CCL21	SCY domain-containing protein. (137 aa)
	M3Y0V5_MUSPF	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (514 aa)
	SFRP2	Secreted frizzled related protein 2. (294 aa)
	FERMT1	Fermitin family member 1. (678 aa)
	M3Y653_MUSPF	Protein kinase domain-containing protein. (212 aa)
	ADAM9	ADAM metallopeptidase domain 9. (785 aa)
	LRRC45	Leucine rich repeat containing 45. (670 aa)
	LIF	LIF interleukin 6 family cytokine. (202 aa)
	SKAP1	Src kinase associated phosphoprotein 1. (363 aa)
	CIB1	Calcium and integrin binding 1. (187 aa)
	IFT74	Intraflagellar transport 74. (600 aa)
	CXCL13	C-X-C motif chemokine. (109 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	RET	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1028 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCL21	CXCL13	ENSMPUP00000004488	ENSMPUP00000016073	SCY domain-containing protein.	C-X-C motif chemokine.	0.643
CD3E	M3Y653_MUSPF	ENSMPUP00000004435	ENSMPUP00000006804	CD3 epsilon antigen.	Protein kinase domain-containing protein.	0.948
CD3E	PTPN6	ENSMPUP00000004435	ENSMPUP00000016662	CD3 epsilon antigen.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.715
CD3E	SKAP1	ENSMPUP00000004435	ENSMPUP00000015195	CD3 epsilon antigen.	Src kinase associated phosphoprotein 1.	0.431
CXCL13	CCL21	ENSMPUP00000016073	ENSMPUP00000004488	C-X-C motif chemokine.	SCY domain-containing protein.	0.643
M3Y653_MUSPF	CD3E	ENSMPUP00000006804	ENSMPUP00000004435	Protein kinase domain-containing protein.	CD3 epsilon antigen.	0.948
M3Y653_MUSPF	PTPN6	ENSMPUP00000006804	ENSMPUP00000016662	Protein kinase domain-containing protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.975
PTPN6	CD3E	ENSMPUP00000016662	ENSMPUP00000004435	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	CD3 epsilon antigen.	0.715
PTPN6	M3Y653_MUSPF	ENSMPUP00000016662	ENSMPUP00000006804	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Protein kinase domain-containing protein.	0.975
PTPN6	RET	ENSMPUP00000016662	ENSMPUP00000017168	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.484
PTPN6	SKAP1	ENSMPUP00000016662	ENSMPUP00000015195	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Src kinase associated phosphoprotein 1.	0.554
RET	PTPN6	ENSMPUP00000017168	ENSMPUP00000016662	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.484
SKAP1	CD3E	ENSMPUP00000015195	ENSMPUP00000004435	Src kinase associated phosphoprotein 1.	CD3 epsilon antigen.	0.431
SKAP1	PTPN6	ENSMPUP00000015195	ENSMPUP00000016662	Src kinase associated phosphoprotein 1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.554