STRINGSTRING
ABL1 ABL1 MAPK3 MAPK3 SETX SETX SIRT1 SIRT1 CAT CAT RELA RELA TRPA1 TRPA1 UCP1 UCP1 NCF1 NCF1 NET1 NET1 ANKZF1 ANKZF1 CHUK CHUK CYP1B1 CYP1B1 TRPM2 TRPM2 FXN FXN RPS3 RPS3 FOS FOS KDM6B KDM6B ANXA1 ANXA1 PDCD10 PDCD10 ECT2 ECT2 AXL AXL OSER1 OSER1 SRC SRC ROMO1 ROMO1 EGFR EGFR M3Z654_MUSPF M3Z654_MUSPF TREX1 TREX1 SOD3 SOD3 JUN JUN MAPK13 MAPK13 PPIF PPIF CCS CCS PJVK PJVK MAP3K5 MAP3K5 ZNF277 ZNF277 TNFAIP3 TNFAIP3 PCGF2 PCGF2 NQO1 NQO1 EZH2 EZH2 SMPD3 SMPD3 MAPK1 MAPK1 PRDX3 PRDX3 SOD1 SOD1 EDN1 EDN1 MAPK9 MAPK9 RIPK1 RIPK1 STK25 STK25 RNF112 RNF112 MAPK7 MAPK7 FANCC FANCC PARK7 PARK7 IMPACT IMPACT SDHAF4 SDHAF4 PDGFRA PDGFRA AQP1 AQP1 M3Y105_MUSPF M3Y105_MUSPF PRDX2 PRDX2 SIGMAR1 SIGMAR1 PDK2 PDK2 ADPRHL2 ADPRHL2 PTPRK PTPRK PPARGC1B PPARGC1B M3YRV1_MUSPF M3YRV1_MUSPF HDAC6 HDAC6 IL6 IL6 SPHK1 SPHK1 PRDX5 PRDX5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABL1Tyrosine-protein kinase. (1150 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
SETXSenataxin. (2682 aa)
SIRT1Sirtuin 1. (557 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
RELARELA proto-oncogene, NF-kB subunit. (511 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1117 aa)
UCP1Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
NCF1Neutrophil cytosolic factor 1. (391 aa)
NET1Neuroepithelial cell transforming 1. (542 aa)
ANKZF1Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (720 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (544 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1496 aa)
FXNFrataxin. (155 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (446 aa)
KDM6BLysine demethylase 6B. (1668 aa)
ANXA1Annexin. (345 aa)
PDCD10Programmed cell death 10. (212 aa)
ECT2Epithelial cell transforming 2. (914 aa)
AXLAXL receptor tyrosine kinase. (887 aa)
OSER1Oxidative stress responsive serine rich 1. (292 aa)
SRCTyrosine-protein kinase. (536 aa)
ROMO1Reactive oxygen species modulator 1. (79 aa)
EGFRReceptor protein-tyrosine kinase. (1207 aa)
M3Z654_MUSPFThioredoxin domain-containing protein. (200 aa)
TREX1Three prime repair exonuclease 1. (313 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (246 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (211 aa)
CCSCopper chaperone for superoxide dismutase. (314 aa)
PJVKPejvakin. (352 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1398 aa)
ZNF277Zinc finger protein 277. (456 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
PCGF2Polycomb group RING finger protein 2. (344 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (395 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (753 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (658 aa)
MAPK1Mitogen-activated protein kinase. (333 aa)
PRDX3Peroxiredoxin 3. (284 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (153 aa)
EDN1Endothelin 1. (202 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (646 aa)
STK25Serine/threonine kinase 25. (426 aa)
RNF112Ring finger protein 112. (605 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
FANCCFanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (563 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
IMPACTImpact RWD domain protein. (318 aa)
SDHAF4Succinate dehydrogenase complex assembly factor 4. (102 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1087 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
M3Y105_MUSPFSuperoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
PRDX2Peroxiredoxin 2. (199 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (223 aa)
PDK2Protein-serine/threonine kinase. (482 aa)
ADPRHL2ADP-ribosylhydrolase like 2. (447 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1463 aa)
PPARGC1BPPARG coactivator 1 beta. (1027 aa)
M3YRV1_MUSPFUncharacterized protein. (286 aa)
HDAC6Histone deacetylase 6. (1199 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa)
SPHK1Sphingosine kinase 1. (386 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (174 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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