(12 nodes) Locomotory exploration behavior network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C12orf10	Chromosome 12 open reading frame 10. (318 aa)
	NLGN2	Neuroligin 2. (661 aa)
	DLG4	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (724 aa)
	PRKCE	Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
	M3YYI0_MUSPF	Uncharacterized protein. (126 aa)
	LRRK2	Leucine rich repeat kinase 2. (2527 aa)
	SLC4A10	Anion exchange protein. (1129 aa)
	M3YYI2_MUSPF	Uncharacterized protein. (111 aa)
	CRBN	Cereblon. (444 aa)
	GAD1	Glutamate decarboxylase 1. (594 aa)
	SHANK3	SH3 and multiple ankyrin repeat domains 3. (1712 aa)
	TNR	Tenascin R. (1358 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLG4	NLGN2	ENSMPUP00000010536	ENSMPUP00000009721	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Neuroligin 2.	0.704
DLG4	SHANK3	ENSMPUP00000010536	ENSMPUP00000001849	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 3.	0.709
M3YYI0_MUSPF	M3YYI2_MUSPF	ENSMPUP00000016390	ENSMPUP00000016392	Uncharacterized protein.	Uncharacterized protein.	0.705
M3YYI2_MUSPF	M3YYI0_MUSPF	ENSMPUP00000016392	ENSMPUP00000016390	Uncharacterized protein.	Uncharacterized protein.	0.705
NLGN2	DLG4	ENSMPUP00000009721	ENSMPUP00000010536	Neuroligin 2.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.704
NLGN2	SHANK3	ENSMPUP00000009721	ENSMPUP00000001849	Neuroligin 2.	SH3 and multiple ankyrin repeat domains 3.	0.675
SHANK3	DLG4	ENSMPUP00000001849	ENSMPUP00000010536	SH3 and multiple ankyrin repeat domains 3.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.709
SHANK3	NLGN2	ENSMPUP00000001849	ENSMPUP00000009721	SH3 and multiple ankyrin repeat domains 3.	Neuroligin 2.	0.675